Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes

C. Wittenbecher,M. Ouni,O. Kuxhaus,M. Jähnert,P. Gottmann,A. Teichmann,K. Meidtner,J. Kriebel,H. Grallert,T. Pischon,H. Boeing,M. Schulze,A. Schürmann

Published 2018 in Diabetes

ABSTRACT

Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentrations and of differential methylation in the IGFBP-2 gene with type 2 diabetes risk.

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