Vitamin D Receptor Gene as a Candidate Gene for Parkinson Disease

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Annals of Human Genetics

• Publication date

  2011-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1469-1809.2010.00631.xPMID 21309754PMCID PMC3077063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Parkinson's disease].

  2022cited by this paper
• Genome‐Wide Association Study Confirms SNPs in SNCA and the MAPT Region as Common Risk Factors for Parkinson Disease

  2010cited by this paper
• Serum vitamin D and the risk of Parkinson disease.

  2010cited by this paper
• A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.

  2009cited by this paper
• Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.

  2009cited by this paper
• Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D

  2009cited by this paper
• Calcium homeostasis, selective vulnerability and Parkinson's disease.

  2009cited by this paper
• The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis.

  2009influential reference
• Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.

  2008cited by this paper
• Prevalence of vitamin d insufficiency in patients with Parkinson disease and Alzheimer disease.

  2008cited by this paper
• A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms

  2008cited by this paper
• Exploring gene-environment interactions in Parkinson’s disease

  2008cited by this paper
• Exploring the Performance of Multifactor Dimensionality Reduction in Large Scale SNP Studies and in the Presence of Genetic Heterogeneity among Epistatic Disease Models

  2008cited by this paper
• Variation in associations between allelic variants of the vitamin D receptor gene and onset of type 1 diabetes mellitus by ambient winter ultraviolet radiation levels: a meta-regression analysis.

  2008cited by this paper
• Calbindin 1, fibroblast growth factor 20, and α-synuclein in sporadic Parkinson’s disease

  2008cited by this paper
• Replication of association between ELAVL4 and Parkinson disease: the GenePD study

  2008cited by this paper
• Polymorphisms of the Tumor Suppressor Gene LSAMP are Associated with Left Main Coronary Artery Disease

  2008cited by this paper
• Nitric oxide synthase genes and their interactions with environmental factors in Parkinson’s disease

  2008cited by this paper
• Vitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis

  2008cited by this paper
• α-Synuclein and Parkinson disease susceptibility

  2007cited by this paper
• Association between vitamin D receptor gene polymorphism and Alzheimer's disease.

  2007influential reference
• Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease.

  2007cited by this paper
• Multiple less common genetic variants explain the association of the cholesteryl ester transfer protein gene with coronary artery disease.

  2007cited by this paper
• alpha-Synuclein and Parkinson disease susceptibility.

  2007cited by this paper
• Molecular markers of early Parkinson's disease based on gene expression in blood

  2007cited by this paper
• Most Published Research Findings Are False—But a Little Replication Goes a Long Way

  2007cited by this paper
• PLINK: a tool set for whole-genome association and population-based linkage analyses.

  2007influential reference
• Alpha-synuclein and Parkinson disease*

  2007cited by this paper
• Parkinson's disease.

  2007cited by this paper
• A new multipoint method for genome-wide association studies by imputation of genotypes

  2007cited by this paper
• Calcitriol Protection against Dopamine Loss Induced by Intracerebroventricular Administration of 6-Hydroxydopamine

  2006cited by this paper
• NOS2A and the modulating effect of cigarette smoking in Parkinson's disease

  2006cited by this paper
• Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.

  2006cited by this paper
• Genetic evidence for ubiquitin‐specific proteases USP24 and USP40 as candidate genes for late‐onset Parkinson disease

  2006cited by this paper
• Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease.

  2006cited by this paper
• Complex segregation analysis of Parkinson's disease: The Mayo Clinic Family Study

  2006cited by this paper
• Behavioural characterization of vitamin D receptor knockout mice.

  2005cited by this paper
• Association of Vitamin D Receptor Gene Polymorphism and Parkinson's Disease in Koreans

  2005influential reference
• VARIATION IN THE VITAMIN D RECEPTOR GENE IS ASSOCIATED WITH MULTIPLE SCLEROSIS IN AN AUSTRALIAN POPULATION

  2005cited by this paper
• Haploview: analysis and visualization of LD and haplotype maps

  2005cited by this paper
• Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease

  2005cited by this paper
• Retracted: Abnormal bone and calcium metabolism in immobilized Parkinson's disease patients

  2005cited by this paper
• Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain.

  2005cited by this paper
• Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease.

  2005cited by this paper
• Susceptibility and outcome in MS

  2004cited by this paper
• Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease.

  2004cited by this paper
• Genetics and biology of vitamin D receptor polymorphisms.

  2004cited by this paper
• Direct brain infusion of glial cell line–derived neurotrophic factor in Parkinson disease

  2003cited by this paper
• Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.

  2003cited by this paper
• Association study of Parkin gene polymorphisms with idiopathic Parkinson disease.

  2003cited by this paper
• Epidemiologic study of 203 sibling pairs with Parkinson’s disease: The GenePD study

  2002cited by this paper
• New clues about vitamin D functions in the nervous system

  2002influential reference
• Epidemiologic study of 203 sibling pairs with Parkinson’s disease

  2002cited by this paper
• New clues about vitamin D functions in the nervous system.

  2002cited by this paper
• Age at onset in two common neurodegenerative diseases is genetically controlled.

  2002cited by this paper
• PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study.

  2002cited by this paper
• Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats.

  2001cited by this paper
• The Polymorphism in the Caudal‐Related Homeodomain Protein Cdx‐2 Binding Element in the Human Vitamin D Receptor Gene

  2001cited by this paper
• Vitamin D: its role and uses in immunology 1

  2001cited by this paper
• Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

  2000cited by this paper
• A test for linkage and association in general pedigrees: the pedigree disequilibrium test.

  2000cited by this paper
• Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles.

  2000cited by this paper
• Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus.

  2000cited by this paper
• Muscle regeneration by bone marrow-derived myogenic progenitors.

  1998cited by this paper
• Genetic Epidemiology of Parkinson's Disease

  1998cited by this paper
• High prevalence of vitamin D deficiency and reduced bone mass in Parkinson's disease [RETRACTED]

  1997cited by this paper
• Functional recovery in parkinsonian monkeys treated with GDNF

  1996cited by this paper
• 1,25‐Dihydroxyvitamin D3, an inducer of glial cell line‐derived neurotrophic factor

  1996cited by this paper
• Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones.

  1993cited by this paper
• Vitamin D-dependent calcium binding proteins: chemistry, distribution, functional considerations, and molecular biology.

  1989cited by this paper
• The steroid and thyroid hormone receptor superfamily.

  1988cited by this paper
• Vitamin D3-Induced Calcium-Binding Protein in Chick Intestinal Mucosa

  1966cited by this paper
• Bmc Medical Genetics Genomewide Association Study for Onset Age in Parkinson Disease

  year unknowninfluential reference

• The Role of Vitamin D in Parkinson's Disease

  2025cites this paper
• The Role of Vitamin D in Parkinson’s Disease: Evidence from Serum Concentrations, Supplementation, and VDR Gene Polymorphisms

  2025influential citation
• Association of 25-hydroxyvitamin D with Parkinson’s disease based on the results from the NHANES 2007 to 2018 and Mendelian randomization analysis

  2025cites this paper
• Vitamin D Receptor Polymorphisms in a Spanish Cohort of Parkinson's Disease Patients

  2024cites this paper
• Vitamin D and focal brain atrophy in PD with non-dementia: a VBM study

  2024cites this paper
• Vitamin D in Central Nervous System: Implications for Neurological Disorders

  2024cites this paper
• Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders.

  2023cites this paper
• Formulation of Lichen Based Pill a Natural Source of Vitamin D3 with a High Absorption Rate by Ambrosiya Neo-Medicine Pvt. Ltd

  2023cites this paper
• Vitamin D deficiency and genetic polymorphisms of vitamin D‐associated genes in Parkinson's disease

  2023cites this paper
• Peculiarities of some candidate gene polymorphisms in Parkinson’s disease

  2023cites this paper
• Co-Administration of Vitamins B12 and D During Pregnancy Have Strong Neuroprotective Effects in Parkinson Disease

  2023cites this paper
• The Vitamin D Receptor as a Potential Target for the Treatment of Age-Related Neurodegenerative Diseases Such as Alzheimer’s and Parkinson’s Diseases: A Narrative Review

  2023cites this paper
• Restorative action of vitamin D3 on motor dysfunction through enhancement of neurotrophins and antioxidant expression in the striatum.

  2022cites this paper
• Vitamin D Alleviates Anxiety and Depression in Elderly People with Prediabetes: A Randomized Controlled Study

  2022cites this paper
• Vitamin D (VD3) Intensifies the Effects of Exercise and Prevents Alterations of Behavior, Brain Oxidative Stress, and Neuroinflammation, in Hemiparkinsonian Rats

  2022cites this paper
• Alzheimer's Disease and the Possible Role of Vitamin D

  2022cites this paper
• Vitamin D and Parkinson’s Disease

  2022cites this paper
• Vitamin D as therapeutic modulator in cerebrovascular diseases: a mechanistic perspectives

  2022cites this paper
• Vitamin D and Focal Brain Atrophy in Parkinson’s Disease With Non-dementia Patients: A Voxel-based Morphometric Study

  2022cites this paper
• Association Between Costochondritis and Vitamin D Deficiency: An Observational Study

  2021cites this paper
• Vitamin D receptor gene polymorphisms and idiopathic Parkinson disease: an Egyptian study

  2021cites this paper
• Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation.

  2021cites this paper
• Diagnosis, Prognosis, Management, Treatment, Research and Advances in Canine Dilated Cardiomyopathy

  2021cites this paper
• Association Between Parkinson’s Disease and Melanoma: Putting the Pieces Together

  2020cites this paper
• Serum vitamin D, vitamin D receptor and binding protein genes polymorphisms in restless legs syndrome

  2020cites this paper
• GALCANEZUMAB – 1-YEAR EXPERIENCE-A REVIEW OF PATIENT CASES AND RELEVANT CLINICAL DATA

  2020cites this paper
• Vitamin D Deficiency and the Risk of Cerebrovascular Disease

  2020cites this paper
• Vitamin D and Hyperkinetic Movement Disorders: A Systematic Review

  2020cites this paper
• Genetic variants of vitamin D metabolism-related DHCR7/NADSYN1 locus and CYP2R1 gene are associated with clinical features of Parkinson’s disease

  2020cites this paper
• FUNCTIONAL EVALUATION OF GAIT IN WISTAR RATS AFTER DEMYELINIZATION WITH ETHIDIUM BROMIDE IN SUPPLEMENTATION OF VITAMIN D

  2020cites this paper
• Association between vitamin D receptor polymorphisms and susceptibility to Parkinson's disease: an updated meta-analysis.

  2020cites this paper
• Vitamin D und Parkinson – Assoziationen und Nutzen

  2020cites this paper
• Vitamin D receptor polymorphisms and the susceptibility of Parkinson's disease.

  2019cites this paper
• Vitamin D receptor rs2228570 polymorphism and Parkinson's disease risk in a Chinese population.

  2019cites this paper
• Blood biomarkers with Parkinson's disease clusters and prognosis: The oxford discovery cohort

  2019cites this paper
• The role of vitamin D receptor gene polymorphisms in the pathogenesis of Behçet's disease: A case‐control study in Turkish population

  2019cites this paper
• Vitamin D receptor genotype influences risk of upper respiratory infection.

  2018cites this paper
• Some genetic factors of Parkinson’s disease in the Hungarian population

  2018cites this paper
• Amyloid Beta 1–42 Alters the Expression of miRNAs in Cortical Neurons

  2018cites this paper
• Vitamin D deficiency in India

  2018cites this paper
• Effect of Vitamin D in Parkinson’s Disease: Current Approaches

  2018cites this paper
• Vitamin D basis of Alzheimer’s disease: from genetics to biomarkers

  2018cites this paper
• Vitamin D receptor gene variants in Parkinson’s disease patients

  2017influential citation
• Studying the Serum Factors Involved in the Metabolism of Vitamin D and Polymorphic Loci of VDR Gene on the Incidence of Parkinson's Disease in Isfahan Population

  2017cites this paper
• Vitamin D receptor gene polymorphisms are associated with multiple sclerosis in Mexican adults.

  2017cites this paper
• Alpha-synuclein, epigenetics, mitochondria, metabolism, calcium traffic, & circadian dysfunction in Parkinson's disease. An integrated strategy for management.

  2017cites this paper
• GC and VDR SNPs and Vitamin D Levels in Parkinson’s Disease: The Relevance to Clinical Features

  2017cites this paper
• Reduced ability of calcitriol to promote augmented dopamine release in the lesioned striatum of aged rats

  2017cites this paper
• KONCENTRACIJA VITAMINA D U DJECE LIJEČENE U KBC-u SPLIT ZBOG NOVODIJAGNOSTICIRANE AKUTNE LIMFOBLASTIČNE LEUKEMIJE

  2017cites this paper
• Emerging preclinical pharmacological targets for Parkinson's disease

  2016cites this paper
• Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson's disease.

  2016cites this paper
• Association of VDR FokI and ApaI genetic polymorphisms with parkinson's disease risk in South Western Iranian population

  2016cites this paper
• Vitamin D receptor gene rs4334089 polymorphism and Parkinson’s disease in Iranian population

  2016cites this paper
• POLYMORPHISM OF VITAMIN D RECEPTOR (VDR) GENE IN SAMPLING OF EUROPEAN RUSSIA AND PRIURALIYE POPULATION

  2016cites this paper
• Single nucleotide polymorphisms in the vitamin D pathway associating with circulating concentrations of vitamin D metabolites and non-skeletal health outcomes: Review of genetic association studies.

  2016cites this paper
• Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.

  2016cites this paper
• Vitamin D: a custodian of cell signalling stability in health and disease.

  2015cites this paper
• Neurologic Manifestations of Systemic Disease ( A Pruitt , Section Editor ) Evidence for the Importance of Vitamin D Status in Neurologic Conditions

  2015cites this paper
• Phytochemicals Safeguard the Genome: Tiny Molecules, Big Role

  2015cites this paper
• Associations between Vitamin D Status, Supplementation, Outdoor Work and Risk of Parkinson’s Disease: A Meta-Analysis Assessment

  2015cites this paper
• Vitamin D cell signalling in health and disease.

  2015cites this paper
• Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure.

  2015cites this paper
• Vitamin D from different sources is inversely associated with Parkinson disease

  2015cites this paper
• Calcium Signalling : The N ext G eneration Calcium Signalling : The Next Generation

  2015cites this paper
• Association of Taq I, Fok I and Apa I polymorphisms in Vitamin D Receptor (VDR) gene with leprosy.

  2015cites this paper
• Vitamin D receptor gene polymorphisms and the risk of Parkinson’s disease

  2015cites this paper
• Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?

  2015cites this paper
• 1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures

  2015cites this paper
• Dietary Factors in the Etiology of Parkinson's Disease

  2015cites this paper
• ApaI, BsmI, FokI, and TaqI Polymorphisms in the Vitamin D Receptor Gene and Parkinson's Disease

  2015cites this paper
• Vitamin D associations and sleep physiology-promising rays of information.

  2015cites this paper
• A review of vitamin D and Parkinson's disease.

  2014cites this paper
• Association between vitamin D receptor gene polymorphisms and susceptibility to Parkinson's disease: a meta-analysis.

  2014cites this paper
• Retraction Note to: Genetic polymorphisms in VDR, ESR1 and ESR2 genes may contribute to susceptibility to Parkinson’s disease: a meta-analysis

  2014cites this paper
• VITAMIN D ACROSS THE LIFE SPAN1

  2014cites this paper
• eview review of vitamin D and Parkinson ’ s disease mie

  2014cites this paper
• Rôles bénéfiques de la vitamine D sur la neurodégénérescence et les troubles mentaux

  2014influential citation
• [Role of vitamin D in the physiopathology of neurodegenerative diseases].

  2014cites this paper
• Beneficial effects of vitamin D on neurodegeneration and mental diseases

  2014cites this paper
• Role de la vitamine D dans la physiopathologie des maladies neurodegeneratives

  2014cites this paper
• 10.5937/specedreh13-4631 = Vitamin D across the life span

  2014cites this paper
• Vitamin D receptor genetic variants and Parkinson's disease in a Taiwanese population.

  2014influential citation
• Plasma vitamin d levels and cognitive function in aging women: The nurses’ health study

  2014cites this paper
• The Influence of Vitamin D Treatment on the Inducible Nitric Oxide Synthase (INOS) Expression in Primary Hippocampal Neurons.

  2014cites this paper
• RETRACTED ARTICLE: Genetic polymorphisms in VDR, ESR1 and ESR2 genes may contribute to susceptibility to Parkinson’s disease: a meta-analysis

  2014cites this paper
• Calcitriol Promotes Augmented Dopamine Release in the Lesioned Striatum of 6-Hydroxydopamine Treated Rats

  2014cites this paper
• Vitamin D and neurocognitive function

  2014cites this paper
• Association of hypovitaminosis D and hypocalcemia with neuropsychiatric disorders.

  2014cites this paper
• The role of vitamin D levels and vitamin D receptor polymorphism on Parkinson's disease in the Faroe Islands.

  2014cites this paper
• Genomic and pharmacogenomic biomarkers of Parkinson's disease.

  2014cites this paper
• Vitamin D as a Potential Therapy in Amyotrophic Lateral Sclerosis

  2014cites this paper
• Why Vitamin D in Alzheimer's Disease? The Hypothesis

  2014cites this paper
• Parkinson disease: Low vitamin D and Parkinson disease—a causal conundrum

  2014cites this paper
• Vitamin D inquiry in hippocampal neurons: consequences of vitamin D-VDR pathway disruption on calcium channel and the vitamin D requirement

  2013cites this paper
• High‐Resolution Survey in Familial Parkinson Disease Genes Reveals Multiple Independent Copy Number Variation Events in PARK2

  2013cites this paper
• Unrecognized vitamin D3 deficiency is common in Parkinson disease

  2013cites this paper
• Beta Amyloid Suppresses the Expression of the Vitamin D Receptor Gene and Induces the Expression of the Vitamin D Catabolic Enzyme Gene in Hippocampal Neurons

  2013cites this paper
• Calcitriol Imparts Neuroprotection In Vitro to Midbrain Dopaminergic Neurons by Upregulating GDNF Expression

  2013cites this paper
• Association of vitamin D receptor gene polymorphisms and Parkinson's disease in Hungarians.

  2013cites this paper
• Microarray Analysis of Transcriptome of Medulla Identifies Potential Biomarkers for Parkinson's Disease

  2013cites this paper