Colocalization of corticotropin-releasing hormone and oestrogen receptor-alpha in the paraventricular nucleus of the hypothalamus in mood disorders.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Brain : a journal of neurology

• Publication date

  2005-06-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1093/BRAIN/AWH448PMID 15705605
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Human Hypothalamus: Basic and Clinical Aspects

  2004cited by this paper
• Hypothalamic-Pituitary-Adrenocortical System and Mood Disorders: Highlights from Mutant Mice

  2004cited by this paper
• Stress of Dying is not Suppressed by High-dose Morphine or by Dementia

  2004cited by this paper
• Estrogen‐receptor‐β distribution in the human hypothalamus: Similarities and differences with ERα distribution

  2003influential reference
• Estrogen-receptor-alpha distribution in the human hypothalamus: similarities and differences with ER alpha distribution

  2003influential reference
• The Human Hypothalamus. Basic and Clinical Aspects : part I: Nuclei of the human hypothalamus.

  2003cited by this paper
• "Serotonin depression"--a biochemical subgroup within the affective disorders?

  2003influential reference
• Close juxtapositions between LHRH immunoreactive neurons and substance P immunoreactive axons in the human diencephalon.

  2002cited by this paper
• Estrogen receptor-alpha distribution in the human hypothalamus in relation to sex and endocrine status.

  2002influential reference
• Estrogen receptor-beta regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice.

  2002cited by this paper
• Sexual Differentiation of the Bed Nucleus of the Stria Terminalis in Humans May Extend into Adulthood

  2002cited by this paper
• The hypothalamic-pituitary-gonadal axis in mood disorders.

  2002cited by this paper
• Depression, endocrinologically a syndrome of premature aging?

  2002cited by this paper
• Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression.

  2001cited by this paper
• Estrogen receptors in the human forebrain and the relation to neuropsychiatric disorders.

  2001cited by this paper
• The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies.

  2001cited by this paper
• Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.

  2001cited by this paper
• Urinary free cortisol excretion in elderly persons with minor and major depression.

  2001cited by this paper
• Cells containing immunoreactive estrogen receptor-alpha in the human basal forebrain.

  2000cited by this paper
• IL-1β immunoreactive neurons in the human hypothalamus: reduced numbers in multiple sclerosis

  2000influential reference
• Estrogen receptor beta (ERbeta) messenger ribonucleic acid (mRNA) expression within the human forebrain: distinct distribution pattern to ERalpha mRNA.

  2000cited by this paper
• Do anxiety and depression have a common pathophysiological mechanism?

  2000cited by this paper
• History and evolution of the monoamine hypothesis of depression.

  2000cited by this paper
• Cerebrospinal fluid corticotropin-releasing hormone in healthy humans: effects of yohimbine and naloxone.

  2000cited by this paper
• Differential expression of estrogen receptor alpha and beta immunoreactivity in the human supraoptic nucleus in relation to sex and aging.

  2000cited by this paper
• Intracerebroventricular corticotropin-releasing factor decreases food intake in white-crowned sparrows.

  2000cited by this paper
• Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression.

  2000influential reference
• The role of corticotropin-releasing factor in depression and anxiety disorders.

  1999cited by this paper
• Developmental traumatology part I: biological stress systems

  1999cited by this paper
• A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems.

  1999cited by this paper
• Activity of Vasopressinergic Neurones of the Human Supraoptic Nucleus os Age‐ and Sex‐Dependent

  1999cited by this paper
• Alcohol and the hypothalamic-pituitary-adrenal axis

  1999cited by this paper
• DHEA and DHEA‐S: A Review

  1999cited by this paper
• The human forebrain has discrete estrogen receptor alpha messenger RNA expression: high levels in the amygdaloid complex.

  1999cited by this paper
• Vasopressin and oxytocin neurons of the human supraoptic and paraventricular nucleus: size changes in relation to age and sex.

  1999cited by this paper
• Childhood sexual abuse as a risk factor for depression in women: psychosocial and neurobiological correlates.

  1999cited by this paper
• Expression of Estrogen Receptor-β Messenger Ribonucleic Acid in Oxytocin and Vasopressin Neurons of the Rat Supraoptic and Paraventricular Nuclei.

  1998cited by this paper
• Major depression in individuals with a history of childhood physical or sexual abuse: relationship to neurovegetative features, mania, and gender.

  1998cited by this paper
• The role of corticotropin releasing factor in depressive illness: a critical review.

  1998cited by this paper
• New insights into the regulation and function of brain estrogen synthase (aromatase).

  1998cited by this paper
• Differential colocalization of estrogen receptor beta (ERbeta) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: an immunocytochemical study.

  1998cited by this paper
• Nitric oxide synthase-containing neurons in the human hypothalamus: reduced number of immunoreactive cells in the paraventricular nucleus of depressive patients and schizophrenics.

  1998cited by this paper
• Comparison of β-protein/A4 deposits and Alz-50-stained cytoskeletal changes in the hypothalamus and adjoining areas of Alzheimer’s disease patients: amorphic plaques and cytoskeletal changes occur independently

  1998cited by this paper
• Expression of estrogen receptor-beta messenger ribonucleic acid in oxytocin and vasopressin neurons of the rat supraoptic and paraventricular nuclei.

  1998cited by this paper
• Antiglucocorticoid treatments in psychiatry.

  1997cited by this paper
• Mood disorders and menopause.

  1997cited by this paper
• Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites.

  1997cited by this paper
• Differential Expression of Estrogen Receptor &agr; and &bgr; Immunoreactivity by Oxytocin Neurons of Rat Paraventricular Nucleus

  1997cited by this paper
• Sexual dimorphism of the human stress response may be due to estradiol-mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis.

  1997influential reference
• Dosing the antipsychotic medication olanzapine.

  1997cited by this paper
• Glucocorticoid feedback resistance.

  1997cited by this paper
• Basic and Clinical Aspects

  1997cited by this paper
• Dr. Nemeroff and the Publishers Reply

  1997cited by this paper
• Differential expression of estrogen receptor alpha and beta immunoreactivity by oxytocin neurons of rat paraventricular nucleus.

  1997cited by this paper
• Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression.

  1996cited by this paper
• Transdermal oestrogen for treatment of severe postnatal depression.

  1996cited by this paper
• Self-reported stressors, symptom complaints and psychobiological functioning-II: Psychoneuroendocrine variables.

  1996cited by this paper
• The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions.

  1996cited by this paper
• Antidepressants and hypothalamic-pituitary-adrenocortical regulation.

  1996influential reference
• Increased activity of hypothalamic corticotropin-releasing hormone neurons in multiple sclerosis.

  1995cited by this paper
• Prophylactic estrogen in recurrent postpartum affective disorder.

  1995cited by this paper
• Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression.

  1995cited by this paper
• Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients.

  1994influential reference
• Epidemiology of depression: Prevalence, risk factors and treatment situation

  1994cited by this paper
• Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior

  1994cited by this paper
• Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction.

  1993cited by this paper
• Localization of corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus of the human hypothalamus; age-dependent colocalization with vasopressin.

  1993cited by this paper
• Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains.

  1992influential reference
• Depression in Women

  1991cited by this paper
• EVOLUTION OF THE MONOAMINE HYPOTHESES OF DEPRESSION

  1991cited by this paper
• Biological aspects of affective disorders

  1991cited by this paper
• Sex- and age-related differences in the activity of testosterone-metabolizing enzymes in microdissected nuclei of the zebra finch brain.

  1990cited by this paper
• Depression in dementia of the Alzheimer type and in multi-infarct dementia.

  1990influential reference
• The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

  1988cited by this paper
• Corticotropin-releasing factor decreases plasma luteinizing hormone levels in female rats by inhibiting gonadotropin-releasing hormone release into hypophysial-portal circulation.

  1987cited by this paper
• Neuroanatomical distribution of testosterone-metabolizing enzymes in the Japanese quail.

  1987cited by this paper
• Depression in women.

  1987cited by this paper
• Hormones and depression

  1987cited by this paper
• Corticotropin-releasing hormone inhibits gonadotropin secretion in the ovariectomized rhesus monkey.

  1987cited by this paper
• The impact of recent stereological advances on quantitative studies of the nervous system.

  1986cited by this paper
• Some catecholamine inhibitors do not cause accumulation of nuclear estrogen receptors in rat hypothalamus and anterior pituitary gland.

  1986influential reference
• GnRH Release from the Mediobasal Hypothalamus

  1986cited by this paper
• GnRH release from the mediobasal hypothalamus. In vitro regulation by oxytocin.

  1986cited by this paper
• α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

  1985influential reference
• Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system.

  1985cited by this paper
• Endogenous opioid peptides and the control of the menstrual cycle.

  1984cited by this paper
• In search of the mode of action of antidepressants. 5-HTP/tyrosine mixtures in depressions.

  1983cited by this paper
• Circular statistics in biology

  1981cited by this paper
• Androgen increases formation of behaviourally effective oestrogen in dove brain

  1981cited by this paper
• Inhibition of luteinizing hormone secretion induced by synthetic LRH by long-term treatment with glucocorticoids in human subjects.

  1975cited by this paper
• Atlas of estradiol‐concentrating cells in the central nervous system of the female rat

  1973cited by this paper
• Population density and reproductive efficiency.

  1971cited by this paper
• Methods for counting neurons

  1970cited by this paper
• Contemporary Research Methods in Neuroanatomy

  1970cited by this paper
• Artifactual displacement of neuronal nucleoli in paraffin sections.

  1967cited by this paper
• Split Nucleoli as A Source of Error in Nerve Cell Counts

  1937cited by this paper
• The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Estrogen Receptor � (ER�) Messenger Ribonucleic Acid (mRNA) Expression within the Human Forebrain: Distinct Distribution Pattern to ER � mRNA*

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1999 by The Endocrine Society Bioavailable Testosterone and Depressed Mood in Older Men: The Rancho Bernardo Study

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Menstrual Abnormalities in Women with Cushing’s Disease Are Correlated with Hypercortisolemia Rather Than Raised Circulating Androgen Levels

  year unknowncited by this paper

• Relationship Between Depression and Epigallocatechin Gallate from the Perspective of Gut Microbiota: A Systematic Review

  2025cites this paper
• Preterm birth: A neuroinflammatory origin for metabolic diseases?

  2024cites this paper
• Exploring the Pathogenesis and Treatment of PSD from the Perspective of Gut Microbiota.

  2024cites this paper
• Investigating the changes in volumes of the limbic system and hypothalamic-subnuclei in patients with depression.

  2024cites this paper
• Peering into the Brain’s Estrogen Receptors: PET Tracers for Visualization of Nuclear and Extranuclear Estrogen Receptors in Brain Disorders

  2023cites this paper
• Hypothalamic subunit volumes in schizophrenia and bipolar spectrum disorders

  2023cites this paper
• Effects of sex and gonadal hormones on manually segmented hypothalamic and pituitary gland volumes in young healthy adults

  2023cites this paper
• Windows into stress: A glimpse at emerging roles for CRHPVN neurons.

  2022cites this paper
• Distinct proteomic profiles in prefrontal subareas of elderly major depressive disorder and bipolar disorder patients

  2022cites this paper
• Progress in Personalized Psychiatric Therapy with the Example of Using Intranasal Oxytocin in PTSD Treatment

  2022cites this paper
• The hypothalamic paraventricular nucleus as a central hub for the estrogenic modulation of neuroendocrine function and behavior.

  2022cites this paper
• Estrogens Play a Critical Role in Stress-Related Gastrointestinal Dysfunction in a Spontaneous Model of Disorders of Gut–Brain Interaction

  2022cites this paper
• Mammillary body and hypothalamic volumes in mood disorders.

  2022cites this paper
• PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression

  2021cites this paper
• Rapid membrane effect of estrogens on stimulation of corticotropin-releasing hormone.

  2020cites this paper
• Perinatal exposure to bisphenol A at the intersection of stress, anxiety, and depression.

  2020cites this paper
• Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations.

  2020cites this paper
• Crosstalk between the microbiota-gut-brain axis and depression

  2020cites this paper
• Expression of MRHR-CRHR1 (Type I CRH Receptor) and the Effects of Prenatal Yoga on Mother Primagravida Trimester III

  2020cites this paper
• The Effects of Prenatal Yoga for Primagravida with Gen Expression mRNA FKBP5 (FK506-binding Protein 51)

  2020cites this paper
• HPA axis- Interaction with Behavioral Systems

  2020cites this paper
• Environment, Lifestyle, and Female Infertility

  2020cites this paper
• Sex differences in stress-related disorders: Major depressive disorder, bipolar disorder, and posttraumatic stress disorder.

  2020cites this paper
• Prefrontal Cortex Corticotropin-Releasing Factor Neurons Motivate Behavioral Coping Strategies During Various Challenging Situations

  2019cites this paper
• Effect of Chronic Corticosterone Treatment on Depression-Like Behavior and Sociability in Female and Male C57BL/6N Mice

  2019cites this paper
• Sex steroid hormones and brain function : PET imaging as a tool for research

  2019cites this paper
• Chronic Unpredictable Mild Stress-Induced Behavioral Changes are Coupled with Dopaminergic Hyperfunction and Serotonergic Hypofunction in Mouse Models of Depression.

  2019cites this paper
• Biological sex classification with structural MRI data shows increased misclassification in transgender women

  2019cites this paper
• Diverse actions of estradiol on anorexigenic and orexigenic hypothalamic arcuate neurons

  2018cites this paper
• The human hypothalamus in mood disorders: The HPA axis in the center

  2018influential citation
• Hypothalamus enlargement in mood disorders

  2018cites this paper
• Sex hormones affect acute and chronic stress responses in sexually dimorphic patterns: Consequences for depression models.

  2018cites this paper
• Sex steroid hormones and brain function: PET imaging as a tool for research

  2018cites this paper
• Transcriptional regulation of corticotropin-releasing hormone gene in stress response

  2018influential citation
• Prefrontal gene expression changes in mood disorders and suicide

  2018cites this paper
• Sex differences in major depression and comorbidity of cardiometabolic disorders: impact of prenatal stress and immune exposures

  2018cites this paper
• Sexually Dimorphic Changes of Hypocretin (Orexin) in Depression

  2017influential citation
• The changes in, and relationship between, plasma nitric oxide and corticotropin‐releasing hormone in patients with major depressive disorder

  2017cites this paper
• Mapping the effects of vitamin D in multiple sclerosis : a 3D perspective

  2017cites this paper
• Gene polymorphisms associated with temperament

  2017cites this paper
• Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis.

  2017cites this paper
• Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease

  2017cites this paper
• Aromatase changes in depression: A postmortem and animal experimental study.

  2017cites this paper
• Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus

  2017cites this paper
• LW-AFC, A New Formula Derived from Liuwei Dihuang Decoction, Ameliorates Cognitive Deterioration and Modulates Neuroendocrine-Immune System in SAMP8 Mouse.

  2017cites this paper
• Pathogenesis and pathogenic mechanisms of depression

  2017cites this paper
• 3.01 – Membrane-Initiated Effects of Estradiol in the Central Nervous System

  2017cites this paper
• Up-regulation of GluR1 in paraventricular nucleus and greater expressions of synapse related proteins in the hypothalamus of chronic unpredictable stress-induced depressive rats.

  2017cites this paper
• Neural - hormonal responses to negative affective stimuli: Impact of dysphoric mood and sex.

  2017cites this paper
• The glucocorticoid receptor in the limbic system of the human brain

  2016cites this paper
• Associations between Metabolic Risk Factors and the Hypothalamic Volume in Childhood Leukemia Survivors Treated with Cranial Radiotherapy

  2016cites this paper
• Network of nuclear receptor ligands in multiple sclerosis: Common pathways and interactions of sex-steroids, corticosteroids and vitamin D3-derived molecules.

  2016cites this paper
• Cellular and molecular mechanisms of sexual differentiation in the mammalian nervous system.

  2016cites this paper
• Elevated Brain-Derived Neurotrophic Factor Correlates Negatively with Severity and Duration of Major Depressive Episodes

  2016cites this paper
• Prenatal stress-immune programming of sex differences in comorbidity of depression and obesity/metabolic syndrome

  2016cites this paper
• The joint power of sex and stress to modulate brain–gut–microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome

  2016cites this paper
• Stress-induced alterations in estradiol sensitivity increase risk for obesity in women.

  2016cites this paper
• HPA Axis Interactions with Behavioral Systems.

  2016cites this paper
• Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus-pituitary-adrenal axis.

  2015cites this paper
• Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

  2015cites this paper
• Sex differences, hormones, and fMRI stress response circuitry deficits in psychoses.

  2015cites this paper
• Minireview: neural signaling of estradiol in the hypothalamus.

  2015cites this paper
• Sex differences in the stress response in SD rats.

  2015cites this paper
• 17β-Estradiol Differentially Regulates Stress Circuitry Activity in Healthy and Depressed Women

  2015influential citation
• Acupoint specificity on acupuncture regulation of hypothalamic- pituitary-adrenal cortex axis function

  2015cites this paper
• Sex differences in the adult HPA axis and affective behaviors are altered by perinatal exposure to a low dose of bisphenol A.

  2014cites this paper
• Antidepressant Effects of Abscisic Acid Mediated by the Downregulation of Corticotrophin-Releasing Hormone Gene Expression in Rats

  2014cites this paper
• Sex differences in the HPA axis.

  2014cites this paper
• Disruption of fetal hormonal programming (prenatal stress) implicates shared risk for sex differences in depression and cardiovascular disease.

  2014influential citation
• Sleep, physical activity, and health in children - a developmental perspective

  2014cites this paper
• Does stress elicit depression? Evidence from clinical and preclinical studies.

  2014cites this paper
• Sex hormones in the modulation of irritable bowel syndrome.

  2014cites this paper
• Stress , gender , and addiction : potential roles of CRF , oxytocin and argininevasopressin

  2014influential citation
• Physical activity and hypothalamic-pituitary-adrenocortical axis function in adolescents.

  2014cites this paper
• Oestradiol Modulates the Effects of Leptin on Energy Homeostasis by Corticotrophin‐Releasing Factor Type 2 Receptor

  2014cites this paper
• Stress, sex, and addiction: potential roles of corticotropin-releasing factor, oxytocin, and arginine-vasopressin

  2014influential citation
• Research review: the role of cytokines in depression in adolescents: a systematic review.

  2013cites this paper
• The role of estrogen in hypothalamic regulation of hypothalamus-pituitary-adrenal axis activity, energy homeostasis and bone metabolism

  2013cites this paper
• All-trans retinoic acid-induced hypothalamus–pituitary–adrenal hyperactivity involves glucocorticoid receptor dysregulation

  2013cites this paper
• Volumetric parcellation methodology of the human hypothalamus in neuroimaging: Normative data and sex differences

  2013cites this paper
• Electroconvulsive seizure-induced changes in gene expression in the mouse hypothalamic paraventricular nucleus

  2013cites this paper
• Sex-dependent pathophysiology as predictors of comorbidity of major depressive disorder and cardiovascular disease

  2013cites this paper
• Orexin: a potential role in the process of obstructive sleep apnea.

  2013cites this paper
• HPA-axis hormone modulation of stress response circuitry activity in women with remitted major depression.

  2013cites this paper
• Decreased NOS1 expression in the anterior cingulate cortex in depression.

  2013cites this paper
• Morphometric differences in central stress-regulating structures between women with and without borderline personality disorder.

  2013cites this paper
• Anorexia nervosa and estrogen receptors.

  2013cites this paper
• Reduced GAD(65/67) immunoreactivity in the hypothalamic paraventricular nucleus in depression: a postmortem study.

  2013cites this paper
• Stress differentially affects fear conditioning in men and women.

  2013cites this paper
• Unaltered histaminergic system in depression: a postmortem study.

  2013cites this paper
• Multiple Origins of Sex Differences in Brain

  2013cites this paper
• Identification and functional characterization of the first two aromatic prenyltransferases implicated in the biosynthesis of furanocoumarins and prenylated coumarins in two plant families: Rutaceae and Apiaceae

  2013cites this paper
• Effects of Sex Differences to Incidence Rate of Major Depressive Disorder

  2013cites this paper
• Antidepressant-like effect of resveratrol: involvement of antioxidant effect and peripheral regulation on HPA axis.

  2013cites this paper
• Sex Differences in HPA and HPG Axes Dysregulation in Major Depressive Disorder: The Role of Shared Brain Circuitry Between Hormones and Mood

  2013cites this paper
• The role of estrogen in hypothalamic regulation of hypothalamus-pituitary-adrenal axis activity , energy homeostasis and bone metabolism

  2013cites this paper
• Membrane-initiated actions of estradiol that regulate reproduction, energy balance and body temperature.

  2012cites this paper
• Bonding after trauma: on the role of social support and the oxytocin system in traumatic stress

  2012cites this paper
• The human histaminergic system in health and neuropsychiatric disorders

  2012cites this paper
• Sex differences in the forebrain.

  2012cites this paper