The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Multiple Sclerosis

• Publication date

  1998-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/135245859800400304PMID 9762657
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1994cited by this paper
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• Second generation immune networks.

  1991cited by this paper
• Affinity distributions of antigen-specific IgG in patients with multiple sclerosis and in patients with viral encephalitis.

  1990cited by this paper
• Chronic relapsing experimental allergic encephalomyelitis: cyclosporin-A treatment of relapsing and remitting disease.

  1986cited by this paper
• New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

  1983cited by this paper
• VIRUS ANTIBODIES IN SERUM SPECIMENS FROM PATIENTS WITH MULTIPLE SCLEROSIS, FROM SIBLINGS, AND MATCHED CONTROLS. A FINAL REPORT *

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• Effects of Biological Sex and Age on Cerebrospinal Fluid Markers-A Retrospective Observational Study.

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• Spinal cord lesions in relapsing-remitting multiple sclerosis: Prognostic value of intrathecal production of immunoglobulins

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• Retrospective In Silico Analysis of Routine Laboratory Data Supports a Specific Association of Epstein–Barr Virus and Multiple Sclerosis

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• Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis?

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• Intrathecal Immunoglobulin A Synthesis in Multiple Sclerosis: From Biological Aspects to Clinical Relevance

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• Cognitive Function and Proteomic Changes in Patients with Autoantibody-Positive Neurodegenerative Dementia

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• Antibodies against SARS-CoV-2 spike protein in the cerebrospinal fluid of COVID-19 patients and vaccinated controls: a multicentre study

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• IgG and kappa free light chain CSF/serum indices: evaluating intrathecal immunoglobulin production in HIV infection in comparison with multiple sclerosis

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• HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis

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• Broad Analysis of Serum and Intrathecal Antimicrobial Antibodies in Multiple Sclerosis Underscores Unique Role of Epstein-Barr Virus

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• MRZ-reaction maybe influenced by immunization status and is not exclusive to multiple sclerosis.

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• Epstein-Barr nuclear antigen 1 antibody-based indices are increased in patients with multiple sclerosis.

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• Multiple Sclerosis and Clostridium perfringens Epsilon Toxin: Is There a Relationship?

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• Disease-related data patterns in cerebrospinal fluid diagnostics: medical quality versus analytical quantity

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• Frequency of an intrathecal IgM synthesis and MRZ reaction in children with MS.

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• Intrathecal immune reactivity against Measles-, Rubella-, and Varicella Zoster viruses is associated with cerebrospinal fluid inflammation in multiple sclerosis

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• Literatur

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• Herpes simplex virus 2 meningitis in adults: A prospective, nationwide, population-based cohort study.

  2022cites this paper
• Cerebrospinal fluid free light chain quantitation is a specific biomarker for inflammatory neurological disorders in a paediatric patient cohort.

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• Spinal fluid antibodies against multiple sclerosis candidate bacteria in demyelinating disease

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• Mass Cytometry of CSF Identifies an MS-Associated B-cell Population

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• Autoantibodies in neurological disease

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• Parvovirus B19 and mumps virus antibodies are major constituents of the intrathecal immune response in European patients with MS and increase the diagnostic sensitivity and discriminatory power of the MRZ reaction

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• Follow-up after infectious mononucleosis in search of serological similarities with presymptomatic multiple sclerosis.

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• Effects of Natalizumab Therapy on Intrathecal Immunoglobulin G Production Indicate Targeting of Plasmablasts

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• Baló's concentric sclerosis - A rare entity within the spectrum of demyelinating diseases.

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• Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern

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• Cerebrospinal Fluid Findings in 541 Patients With Clinically Isolated Syndrome and Multiple Sclerosis: A Monocentric Study

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• Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Detailed Review of the Different Psychiatric Presentations and Red Flags to Look for in Suspected Cases

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• Neurofilament light chain as a biomarker for diagnosis of multiple sclerosis

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• The Diagnostic Significance of Intrathecal Synthesis of Antibodies Against Measles, Rubella, and Varicella Zoster Viruses in the Differential Diagnosis of Demyelinating Diseases of the Central Nervous System

  2020cites this paper
• Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis

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• The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

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• Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

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• IgG Index Revisited: Diagnostic Utility and Prognostic Value in Multiple Sclerosis

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• Genetic determinants of the humoral immune response in MS

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• Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients

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• ДИАГНОСТИЧЕСКАЯ ЗНАЧИМОСТЬ ИНТРАТЕКАЛЬНОГО СИНТЕЗА ИММУНОГЛОБУЛИНОВ ПРОТИВ ВИРУСОВ КОРИ, КРАСНУХИ И ВЕТРЯНОЙ ОСПЫ В ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКЕ ДЕМИЕЛИНИЗИРУЮЩИХ ЗАБОЛЕВАНИЙ ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ

  2020influential citation
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• CSF biomarkers in multiple sclerosis: beyond neuroinflammation

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• Liquordiagnostik

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• The role of viral infections in the development of autoimmune diseases

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• Intrathecal inflammation in young stroke

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• Friend or foe? – B cells in stroke

  2019influential citation
• Effects of natalizumab therapy on intrathecal antiviral antibody responses in MS

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• Medicinal Chemistry of Multiple Sclerosis: Focus on Cladribine.

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• Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis

  2019influential citation
• The Role of B Cells and Antibodies in Multiple Sclerosis, Neuromyelitis Optica, and Related Disorders

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• Association of cerebrospinal fluid kappa free light chains with the intrathecal polyspecific antiviral immune response in multiple sclerosis.

  2019cites this paper
• Diagnostic relevance of free light chains in cerebrospinal fluid - The hyperbolic reference range for reliable data interpretation in quotient diagrams.

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• B cells in autoimmune and neurodegenerative central nervous system diseases

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• Myelinoclastic diffuse sclerosis (Schilder’s disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures

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• Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination

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  2018influential citation
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