Glyoxal causes inflammatory injury in human vascular endothelial cells.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2008-05-16

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.bbrc.2008.03.020PMID 18343213
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inflammation in Atherosclerosis

  2012cited by this paper
• The endothelium and vascular inflammation in diabetes

  2007cited by this paper
• Hyperglycaemia and cardiovascular disease

  2007cited by this paper
• Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity.

  2007cited by this paper
• Atherosclerosis in diabetes mellitus: role of inflammation.

  2007cited by this paper
• Acrolein Induces Cyclooxygenase-2 and Prostaglandin Production in Human Umbilical Vein Endothelial Cells: Roles of p38 MAP Kinase

  2007cited by this paper
• Cyclooxygenase-2 Induction and Prostacyclin Release by Protease-activated Receptors in Endothelial Cells Require Cooperation between Mitogen-activated Protein Kinase and NF-κB Pathways*

  2006cited by this paper
• Endothelial Nitric Oxide Synthase in Vascular Disease: From Marvel to Menace

  2006cited by this paper
• Cytotoxicity of water-soluble fullerene in vascular endothelial cells.

  2006cited by this paper
• Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.

  2006cited by this paper
• High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.

  2006cited by this paper
• Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.

  2006cited by this paper
• Substance P‐induced cyclooxygenase‐2 expression in human umbilical vein endothelial cells

  2006cited by this paper
• Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E2 Expression through JAK-STAT Activation in Human Colonic Epithelial Cells1

  2006cited by this paper
• Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells.

  2005cited by this paper
• Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells.

  2005cited by this paper
• High Glucose Induces Human Endothelial Cell Apoptosis Through a Phosphoinositide 3-Kinase–Regulated Cyclooxygenase-2 Pathway

  2005cited by this paper
• Binding of receptor for advanced glycation end products (RAGE) ligands is not sufficient to induce inflammatory signals: lack of activity of endotoxin-free albumin-derived advanced glycation end products

  2004cited by this paper
• Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells

  2004cited by this paper
• Glyoxal and Methylglyoxal Levels in Diabetic Patients: Quantitative Determination by a New GC/MS Method

  2003cited by this paper
• Diabetes-Induced Oxidative Stress and Low-Grade Inflammation in Porcine Coronary Arteries

  2003cited by this paper
• Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE: A Mechanism for Amplification of Inflammatory Responses

  2002cited by this paper
• Inflammation in atherosclerosis

  2002cited by this paper
• NO regulates LPS-stimulated cyclooxygenase gene expression and activity in pulmonary artery endothelium.

  2001cited by this paper
• Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells.

  2001cited by this paper
• Glyoxal and methylglyoxal induce lyoxal and methyglyoxal induce aggregation and inactivation of ERK in human endothelial cells.

  2001cited by this paper
• Serum concentrations of advanced glycation endproducts are associated with the development of atherosclerosis as well as diabetic microangiopathy in patients with type 2 diabetes

  2000cited by this paper
• Atherosclerosis--an inflammatory disease.

  1999cited by this paper
• Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease.

  1999cited by this paper
• EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology.

  1999cited by this paper
• Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.

  1998cited by this paper
• Increased serum levels of advanced glycation end-products and diabetic complications.

  1998cited by this paper
• NITRIC OXIDE PHYSIOLOGY

  1997cited by this paper
• Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1.

  1996cited by this paper
• Nitric oxide: physiology, pathophysiology, and pharmacology.

  1991cited by this paper
• Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

  1989cited by this paper

• The Impacts of Vaping on the Cardiovascular System: A Systematic Review of Case Reports

  2025cites this paper
• Menaquinone-7 Supplementation Increases Multiple Advanced Glycation End-Products and Oxidation Markers in Zucker Diabetic Fatty Rats

  2025cites this paper
• Betulinic acid exerts anti-inflammatory activity in human periodontal ligament cells stimulated with lipopolysaccharide and/or high glucose.

  2022cites this paper
• An in vitro cell model to study microglia activation in diabetic retinopathy

  2021cites this paper
• In-Depth AGE and ALE Profiling of Human Albumin in Heart Failure: Ex Vivo Studies

  2021cites this paper
• Associations of dicarbonyl stress with complement activation: the CODAM study

  2020cites this paper
• Mapping sites of carboxymethyllysine modification on proteins reveals its consequences for proteostasis and cell proliferation

  2020cites this paper
• Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells

  2020cites this paper
• Formation of Toxic Glyoxal, Methylglyoxal, and Diacetyl Formed in the Headspace of Heated Edible Oils

  2019cites this paper
• Signal and regulatory effects of methylglyoxal in eukaryotic cells (review)

  2017cites this paper
• Effects of plant-derived polyphenols on glycation and oxidative stress related to vascular diseases

  2017cites this paper
• Amplification of AngII-dependent cell contraction by glyoxal: implication of cell mechanical properties and actomyosin activity.

  2014cites this paper
• Mechanisms of Methylglyoxal-elicited Leukocyte Recruitment

  2014cites this paper
• Negative inotropic effect of carbachol and interaction between acetylcholine receptor-operated potassium channel (K.ACh channel) and GTP binding protein in mouse isolated atrium--a novel methodological trial.

  2013cites this paper
• Vaspin prevents methylglyoxal‐induced apoptosis in human vascular endothelial cells by inhibiting reactive oxygen species generation

  2013cites this paper
• Long-term methylglyoxal treatment causes endothelial dysfunction of rat isolated mesenteric artery.

  2013cites this paper
• Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal.

  2013cites this paper
• A novel adipocytokine, chemerin exerts anti-inflammatory roles in human vascular endothelial cells.

  2012cites this paper
• Exploring mechanisms of diabetes-related macrovascular complications: role of methylglyoxal, a metabolite of glucose on regulation of vascular contractility.

  2012cites this paper
• Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats.

  2012cites this paper
• EPO attenuates inflammatory cytokines by Muller cells in diabetic retinopathy.

  2011cites this paper
• Production et caractérisation de biocatalyseurs insolubles et laccase par l'action du chitosane comme agent de réticulation

  2011cites this paper
• Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells.

  2011cites this paper
• Advanced glycation end product precursors in diabetes : a crucial link between oxidative stress and inflammation?

  2010cites this paper
• EFEITO DO GLICOLALDEÍDO SOBRE PARÂMETROS DE COAGULAÇÃO E DANOS PROTEICOS

  2010cites this paper
• Carbonyl compounds methylglyoxal and glyoxal affect interleukin-8 secretion in intestinal cells by superoxide anion generation and activation of MAPK p38.

  2010cites this paper
• Involvement of Cyclooxygenase-2 in Carbachol-Induced Positive Inotropic Response in Mouse Isolated Left Atrium

  2009cites this paper
• Vaspin Can Not Inhibit TNF-α-Induced Inflammation of Human Umbilical Vein Endothelial Cells

  2009cites this paper
• Vaspin can not inhibit TNF-alpha-induced inflammation of human umbilical vein endothelial cells.

  2009cites this paper
• Telmisartan inhibits methylglyoxal-mediated cell death in human vascular endothelium.

  2008cites this paper
• Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells.

  2008influential citation