A Multi-Functional Tubulovesicular Network as the Ancestral Eukaryotic Endomembrane System

The origin of the eukaryotic endomembrane system is still the subject of much speculation. We argue that the combination of two recent hypotheses addressing the eukaryotic endomembrane’s early evolution supports the possibility that the ancestral membranes were organised as a multi-functional tubulovesicular network. One of the potential selective advantages provided by this organisation was the capacity to perform endocytosis. This possibility is illustrated by membrane organisations observed in current organisms in the three domains of life. Based on this, we propose a coherent model of autogenous eukaryotic endomembrane system evolution in which mitochondria are involved at a late stage.

• Publication year

  2015

• Venue

  Biology

• Publication date

  2015-03-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3390/biology4020264PMID 25811639PMCID 4498299
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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