DNA methylation of Th2 lineage determination genes at birth is associated with allergic outcomes in childhood

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Clinical and Experimental Allergy

• Publication date

  2017-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/cea.12988PMID 28756630PMCID PMC5681244
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock

  2017cited by this paper
• Mesenteric IL-10-producing CD5+ regulatory B cells suppress cow’s milk casein-induced allergic responses in mice

  2016cited by this paper
• IL-10 Enhances IgE-Mediated Mast Cell Responses and Is Essential for the Development of Experimental Food Allergy in IL-10–Deficient Mice

  2016cited by this paper
• DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

  2016cited by this paper
• Omalizumab facilitates rapid oral desensitization for peanut allergy

  2016cited by this paper
• Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure

  2016cited by this paper
• Differential TLR‐induced cytokine production by human mast cells is amplified by FcɛRI triggering

  2015cited by this paper
• Toll-like receptors as targets for allergen immunotherapy

  2015cited by this paper
• Loss of IL‐4Rα–mediated PI3K signaling accelerates the progression of IgE/mast cell–mediated reactions

  2015cited by this paper
• Atopic Dermatitis in Early Life: Evidence for at Least Three Phenotypes? Results from the GUSTO Study

  2015cited by this paper
• Interleukin-10–producing CD5+ B cells inhibit mast cells during immunoglobulin E–mediated allergic responses

  2015cited by this paper
• coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns

  2015cited by this paper
• Oral immunotherapy for the treatment of peanut allergy: is it ready for prime time?

  2014cited by this paper
• State of the art on food allergen immunotherapy: oral, sublingual, and epicutaneous.

  2014cited by this paper
• Trends in hospitalizations for food-induced anaphylaxis in US children, 2000-2009.

  2014cited by this paper
• Smoke exposure as a risk factor for asthma in childhood: a review of current evidence.

  2014cited by this paper
• IFN-α Suppresses GATA3 Transcription from a Distal Exon and Promotes H3K27 Trimethylation of the CNS-1 Enhancer in Human Th2 Cells

  2014cited by this paper
• Multiple hypothesis testing in genomics

  2014cited by this paper
• Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report.

  2013cited by this paper
• Relevance of pre- and postnatal nutrition to development and interplay between the microbiota and metabolic and immune systems.

  2013cited by this paper
• The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

  2013influential reference
• Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanism.

  2013cited by this paper
• Prenatal food allergen exposures and odds of childhood peanut, tree nut, or sesame seed sensitization.

  2013cited by this paper
• A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients.

  2013cited by this paper
• About the role and underlying mechanisms of cofactors in anaphylaxis

  2013cited by this paper
• Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice.

  2012cited by this paper
• Differentially Methylated Regions of Imprinted Genes in Prenatal, Perinatal and Postnatal Human Tissues

  2012cited by this paper
• FcεR1-Mediated Mast Cell Reactivity Is Amplified through Prolonged Toll-Like Receptor-Ligand Treatment

  2012cited by this paper
• DNA methylation arrays as surrogate measures of cell mixture distribution

  2012cited by this paper
• New developments in Toll-like receptor targeted therapeutics.

  2012cited by this paper
• Lipopolysaccharide enhances FcɛRI‐mediated mast cell degranulation by increasing Ca2+ entry through store‐operated Ca2+ channels: implications for lipopolysaccharide exacerbating allergic asthma

  2012cited by this paper
• TLR signaling in mast cells: common and unique features

  2012cited by this paper
• The role of epigenetic dysregulation in the epidemic of allergic disease

  2011cited by this paper
• Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells

  2011cited by this paper
• Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis

  2011cited by this paper
• Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond.

  2011cited by this paper
• Blockade of cysteinyl leukotriene‐1 receptors suppresses airway remodelling in mice overexpressing GATA‐3

  2011cited by this paper
• Single early prenatal lipopolysaccharide exposure prevents subsequent airway inflammation response in an experimental model of asthma.

  2011cited by this paper
• World Allergy Organization anaphylaxis guidelines: summary.

  2011cited by this paper
• Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy.

  2011cited by this paper
• Pathogen Recognition by the Innate Immune System

  2011cited by this paper
• Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease

  2010cited by this paper
• Asthma: Clinical expression and molecular mechanisms

  2010cited by this paper
• Lipopolysaccharide-Mediated Mast Cell Activation Induces IFN-γ Secretion by NK Cells

  2010cited by this paper
• Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

  2010cited by this paper
• Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis.

  2010cited by this paper
• Mast cell-orchestrated immunity to pathogens

  2010cited by this paper
• Mast cells are necessary for the hypothermic response to LPS-induced sepsis.

  2009cited by this paper
• Relation of DNA Methylation of 5′-CpG Island of ACSL3 to Transplacental Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Childhood Asthma

  2009cited by this paper
• At the crossroads of T helper lineage commitment-Epigenetics points the way.

  2009cited by this paper
• Transcriptional Regulation of Gata3 in T Helper Cells by the Integrated Activities of Transcription Factors Downstream of the Interleukin-4 Receptor and T Cell Receptor*

  2009cited by this paper
• A TLR2 Ligand Suppresses Allergic Inflammatory Reactions by Acting Directly on Mast Cells

  2009cited by this paper
• Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

  2009cited by this paper
• NF-kappaB as a critical link between inflammation and cancer.

  2009cited by this paper
• Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands

  2009cited by this paper
• Pathogen recognition in the innate immune response.

  2009cited by this paper
• Anaphylaxis in referred pediatric patients: demographic and clinical features, triggers, and therapeutic approach

  2008cited by this paper
• The modulatory effects of lipopolysaccharide‐stimulated B cells on differential T‐cell polarization

  2008cited by this paper
• IL-10 Suppresses Mast Cell IgE Receptor Expression and Signaling In Vitro and In Vivo1

  2008cited by this paper
• IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

  2008cited by this paper
• Advances in asthma and allergy genetics in 2007.

  2008cited by this paper
• Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood

  2008cited by this paper
• High dose of lipopolysaccharide pre-treatment prevents OVA-induced anaphylactic decreases in rectal temperature in the immunized mice.

  2008cited by this paper
• Developmental mismatch: consequences for later cardiorespiratory health.

  2008cited by this paper
• Transcription factors T-bet and GATA-3 regulate development of airway remodeling

  2007cited by this paper
• Anaphylaxis: lessons from mouse models.

  2007cited by this paper
• Stimulation of mast cells via FcvarepsilonR1 and TLR2: the type of ligand determines the outcome.

  2007cited by this paper
• Notch directly regulates Gata3 expression during T helper 2 cell differentiation.

  2007cited by this paper
• Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals.

  2007cited by this paper
• Signaling to NF-kappaB by Toll-like receptors.

  2007cited by this paper
• Oral bacterial lipopolysaccharide acts in mice to promote sensitisation to ovalbumin and to augment anaphylaxis via platelets.

  2007cited by this paper
• Review article: Developmental mismatch: consequences for later cardiorespiratory health

  2007cited by this paper
• Lipoteichoic acid downregulates FcepsilonRI expression on human mast cells through Toll-like receptor 2.

  2007cited by this paper
• Innate immunity of the newborn: basic mechanisms and clinical correlates

  2007cited by this paper
• Toll-like receptors and innate immunity

  2006cited by this paper
• Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

  2006cited by this paper
• Cohort profile: The Southampton Women's Survey.

  2006cited by this paper
• FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells.

  2006cited by this paper
• New insights into the molecular mechanism of interleukin‐10‐mediated immunosuppression

  2005cited by this paper
• Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes.

  2005cited by this paper
• Impaired FcεRI-Dependent Gene Expression and Defective Eicosanoid and Cytokine Production as a Consequence of Fyn Deficiency in Mast Cells1

  2005cited by this paper
• Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

  2005cited by this paper
• IL-10 inhibits Fc epsilon RI expression in mouse mast cells.

  2004cited by this paper
• The two NF-kappaB activation pathways and their role in innate and adaptive immunity.

  2004cited by this paper
• Toll-like receptor signalling

  2004cited by this paper
• TLR3-, TLR7-, and TLR9-Mediated Production of Proinflammatory Cytokines and Chemokines from Murine Connective Tissue Type Skin-Derived Mast Cells but Not from Bone Marrow-Derived Mast Cells 1

  2004cited by this paper
• Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3.

  2004cited by this paper
• The function role of GATA-3 in Th1 and Th2 differentiation

  2003influential reference
• Exposure to endotoxin and allergen in early life and its effect on allergen sensitization in mice.

  2003cited by this paper
• Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and FcepsilonRI.

  2003cited by this paper
• IL-4 Exacerbates Anaphylaxis 1

  2003cited by this paper
• Anaphylaxis: risk factors for recurrence

  2003cited by this paper
• Toll‐like receptor 2 (TLR2) and TLR4 differentially activate human mast cells

  2003cited by this paper
• Toll-Like Receptor Signaling Pathways

  2003cited by this paper
• Cutting Edge: Distinct Toll-Like Receptor 2 Activators Selectively Induce Different Classes of Mediator Production from Human Mast Cells 12

  2003cited by this paper
• Endotoxins prevent murine IgE production, T(H)2 immune responses, and development of airway eosinophilia but not airway hyperreactivity.

  2002cited by this paper
• Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity.

  2002cited by this paper
• The immunopathogenesis of sepsis

  2002cited by this paper
• Pathways of anaphylaxis in the mouse.

  2002cited by this paper
• Stat6 Is Necessary and Sufficient for IL-4’s Role in Th2 Differentiation and Cell Expansion

  2001cited by this paper

• Receptor de muerte programada 1 (PD-1): un blanco terapéutico novedoso en dermatitis atópica

  2026cites this paper
• The GATA3-STEAP4 Axis Drives Inflammation by Promoting Th2 Differentiation in Allergic Rhinitis

  2025cites this paper
• Newborn blood DNA methylation and childhood asthma: findings from the ECHO program

  2025cites this paper
• Understanding the childhood origins of asthma and COPD: insights from birth cohorts and studies across the lifespan.

  2025cites this paper
• An Encompassing Review on Therapeutic Targets, Therapies and Nanostructure Based Formulations for Atopic Dermatitis

  2024cites this paper
• Anti-inflammation of LZTFL1 knockdown in OVA-induced asthmatic mice: Through ERK/GATA3 signaling pathway.

  2024cites this paper
• From small to big, using microRNA profiling to investigate infant origins of childhood asthma

  2023cites this paper
• Intrinsic Effects of Exposome in Atopic Dermatitis: Genomics, Epigenomics and Regulatory Layers

  2023cites this paper
• Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors with immune process related function.

  2023cites this paper
• Grandmaternal allergen exposure causes distinct epigenetic trajectories in offspring associated with airway hyperreactivity and inflammation

  2022cites this paper
• A pathogenic integrated view explaining the different endotypes of asthma and allergic disorders

  2022cites this paper
• Asthma and the Missing Heritability Problem: Necessity for Multiomics Approaches in Determining Accurate Risk Profiles

  2022cites this paper
• Molecular networks in atopic mothers impact the risk of infant atopy

  2022cites this paper
• Epigenetics and precision medicine in allergic diseases

  2022cites this paper
• The Foetal Origins of Allergy and Potential Nutritional Interventions to Prevent Disease

  2022cites this paper
• Understanding Asthma and Allergies by the Lens of Biodiversity and Epigenetic Changes

  2021cites this paper
• Skin epigenetics

  2021cites this paper
• Inflammation in Asthma Pathogenesis: Role of T cells, Macrophages, Epithelial Cells and Type 2 Inflammation.

  2021cites this paper
• Role of Epigenetics in the Pathogenesis, Treatment, Prediction, and Cellular Transformation of Asthma

  2021cites this paper
• ESR2 regulates PINK1-mediated mitophagy via transcriptional repression of microRNA-423 expression to promote asthma development.

  2021cites this paper
• Probiotics for Atopic Dermatitis: An Update

  2021cites this paper
• Sophora flavescens Alkaloids and Corticosteroid Synergistically Augment IL-10/IL-5 Ratio with Foxp3-Gene-Epigenetic Modification in Asthma PBMCs

  2021cites this paper
• Co-exposure to different sized polystyrene microplastics and benzo[a]pyrene affected inflammation in zebrafish andbronchial-associated cells

  2020cites this paper
• Recent findings in the genetics and epigenetics of asthma and allergy

  2020cites this paper
• Epigenetic factors involved in the pathophysiology of inflammatory skin diseases.

  2020cites this paper
• Epigenetics and the Environment in Airway Disease: Asthma and Allergic Rhinitis.

  2020cites this paper
• The Role of T Cells and Macrophages in Asthma Pathogenesis: A New Perspective on Mutual Crosstalk

  2020cites this paper
• Epigenetic methylation in Eosinophilic Esophagitis: Molecular ageing and novel biomarkers for treatment response

  2020cites this paper
• Epigenetic alterations in skin homing CD4+CLA+ T cells of atopic dermatitis patients

  2020cites this paper
• Pathophysiology of atopic dermatitis: Clinical implications.

  2019cites this paper
• Epigenetics in Asthma

  2019cites this paper
• The atopic march and atopic multimorbidity: Many trajectories, many pathways

  2019cites this paper
• Call for papers for special issue in 2020

  2019cites this paper
• Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

  2019cites this paper
• Epigenetic biomarkers of asthma and allergic disorders

  2019cites this paper
• The Cytokines of Asthma.

  2019cites this paper
• The Effects of the Environment on Asthma Disease Activity.

  2019cites this paper
• Methyl-Donor and Cofactor Nutrient Intakes in the First 2–3 Years and Global DNA Methylation at Age 4: A Prospective Cohort Study

  2018cites this paper
• Documentation des patrons de méthylation et d'expression de gènes de la voie biologique de l'interleukine-33 dans l'asthme

  2018cites this paper
• Developments in the field of allergy in 2017 through the eyes of Clinical and Experimental Allergy

  2018cites this paper
• Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma.

  2018cites this paper
• Role of epigenetics in the development of childhood asthma

  2018cites this paper
• Validation of the MASK‐rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control

  2017cites this paper
• Asthma, urticaria and less rare than expected FPIES

  2017cites this paper