Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Allergy and Clinical Immunology

• Publication date

  1993-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0091-6749(93)90078-TPMID 8409114
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Safety of bronchoalveolar lavage and bronchial biopsies in patients with asthma of variable severity.

  1992cited by this paper
• Airway mucosal inflammation in occupational asthma induced by toluene diisocyanate.

  1992cited by this paper
• Application of monoclonal antibodies against major basic protein (BMK‐13) and eosinophil cationic protein (EG1 and EG2) for quantifying eosinophils in bronchial biopsies from atopic asthma

  1992cited by this paper
• Immunohistochemical characterization of the cellular infiltration in asthmatic bronchi.

  1992cited by this paper
• Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry.

  1992cited by this paper
• Neutrophil chemotactic factors in the respiratory tract of patients with chronic airway diseases or idiopathic pulmonary fibrosis.

  1992cited by this paper
• Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

  1991cited by this paper
• Indirect evidence of bronchial inflammation assessed by titration of inflammatory mediators in BAL fluid of patients with asthma.

  1991cited by this paper
• Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness.

  1991cited by this paper
• Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease.

  1991cited by this paper
• Bronchoalveolar lavage constituents in healthy individuals, idiopathic pulmonary fibrosis, and selected comparison groups. The BAL Cooperative Group Steering Committee.

  1990cited by this paper
• A comparison of albumin and urea as reference markers in bronchoalveolar lavage fluid from patients with interstitial lung disease.

  1990cited by this paper
• Short-term smoking reduction is associated with reduction in measures of lower respiratory tract inflammation in heavy smokers.

  1990cited by this paper
• Effects of corticosteroids in "chronic bronchitis" and "chronic obstructive airway disease".

  1990cited by this paper
• The neutrophil and chronic allergic inflammation. Immunochemical localization of neutrophil elastase.

  1990cited by this paper
• Pathology of chronic airflow obstruction.

  1990cited by this paper
• Eosinophilic inflammation in asthma.

  1990cited by this paper
• Mucosal inflammation in asthma.

  1990cited by this paper
• Sputum cell counts in airway disease: a useful sampling technique.

  1990cited by this paper
• Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters.

  1989cited by this paper
• The role of allergy and nonspecific airway hyperresponsiveness in the pathogenesis of chronic obstructive pulmonary disease.

  1989cited by this paper
• Intraepithelial T-lymphocyte subsets in the airways of normal subjects and of patients with chronic bronchitis.

  1989cited by this paper
• Use of monoclonal antibody against human neutrophil elastase in normal and leukaemic myeloid cells.

  1988cited by this paper
• Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986.

  1987cited by this paper
• Anatomical distribution of bronchoalveolar lavage fluid as assessed by digital subtraction radiography.

  1987cited by this paper
• Eosinophils, smoking, and lung function. An epidemiologic survey among 912 working men.

  1986cited by this paper
• Corticosteroids in COPD. A clinical trial and reassessment of the literature.

  1986cited by this paper
• The effects of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage.

  1985cited by this paper
• Reassessment of inflammation of airways in chronic bronchitis.

  1985cited by this paper
• Cigarette smoking causes accumulation of polymorphonuclear leukocytes in alveolar septum.

  1985cited by this paper
• Cigarette smoking and lung destruction: accumulation of neutrophils in the lungs of cigarette smokers

  1983cited by this paper
• Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers.

  1983cited by this paper
• Heterogeneity of Bronchial Asthma

  1981cited by this paper
• Radioimmunoassay of Human Eosinophil Cationic Protein

  1977cited by this paper
• Pathologic changes in the peripheral airways of young cigarette smokers.

  1974cited by this paper
• A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema

  1969cited by this paper
• Some histological changes in chronic bronchitis and asthma

  1968cited by this paper
• Bronchial Biopsy in Chronic Bronchitis and Asthma

  1960cited by this paper

• A Novel Strategy Based on Serum Metabolite-Mediated Interactions Between the Lung and Gut Microbiota to Investigate the Protective Effect of Flos Farfarae Against Chronic Bronchitis.

  2026cites this paper
• Research advances in polyphenols from Chinese herbal medicine for the prevention and treatment of chronic obstructive pulmonary disease: a review

  2025cites this paper
• Patterns and Underlying Mechanisms of Airway Epithelial Cell Death in COPD

  2025cites this paper
• The Role of CD68+ Cells in Bronchoalveolar Lavage Fluid for the Diagnosis of Respiratory Diseases

  2025cites this paper
• Myeloperoxidase as a Biomarker in COPD.

  2025cites this paper
• On the Ocean of Biomarkers for the Precise Diagnosis and Prognosis of Lung Diseases

  2025cites this paper
• The relevance of eosinophils in chronic obstructive pulmonary disease: inflammation, microbiome and clinical outcomes.

  2024cites this paper
• Fine particulate matter contributes to COPD-like pathophysiology: experimental evidence from rats exposed to diesel exhaust particles

  2024cites this paper
• Network Pharmacology and Molecular Docking Reveal Anti-Asthmatic Potential of Zephyranthes rosea Lindl. in an Ovalbumin-Induced Asthma Model

  2024cites this paper
• Immune Dysregulation in Chronic Obstructive Pulmonary Disease

  2024influential citation
• Εosinophilic Chronic Obstructive Pulmonary Disease. What Do We Know So Far?

  2024cites this paper
• Small airways disease in chronic obstructive pulmonary disease

  2024cites this paper
• Association between blood eosinophil count and small airway eosinophils in smokers with and without COPD

  2023cites this paper
• Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study

  2023cites this paper
• Bronchoalveolar Lavage Fluid from Chronic Obstructive Pulmonary Disease Patients Increases Neutrophil Chemotaxis Measured by a Microfluidic Platform

  2023cites this paper
• The Role of Serum Myeloperoxidase in Prediction of Severe Bronchial Asthma

  2023cites this paper
• The Dynamic Contribution of Neutrophils in the Chronic Respiratory Diseases

  2022cites this paper
• Serum Myeloperoxidase as a Biomarker of Asthma Severity Among Adults: A Case Control Study.

  2022cites this paper
• Involvement of the Innate Immune System in the Pathogenesis of Chronic Obstructive Pulmonary Disease

  2022cites this paper
• Epithelial Barrier Dysfunction in Chronic Respiratory Diseases

  2021cites this paper
• HIV induces airway basal progenitor cells to adopt an inflammatory phenotype

  2021cites this paper
• Targeting Molecular and Cellular Mechanisms in Chronic Obstructive Pulmonary Disease

  2021cites this paper
• Narrative Literature Review Guided Approach of Inhaled Corticosteroid de-escalation in Chronic Obstructive Pulmonary Disease

  2021cites this paper
• Analysis of Asthmatic Lung Remodeling in Summer Pasture-Associated Recurrent Airway Obstruction

  2021cites this paper
• Chronic Obstructive Pulmonary Disease: Molecular Basis of Pathogenesis and Targeted Therapeutic Approaches

  2021cites this paper
• Hypericum ascyron L. extract reduces particulate matter‐induced airway inflammation in mice

  2020cites this paper
• Suppressive effect of environmental tobacco smoke on murine Th2 cell-mediated nasal eosinophilic inflammation

  2020cites this paper
• Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

  2020cites this paper
• Polyherbal formula SC-E3 inhibits rheumatoid arthritis activity in a mouse model of type-II collagen-induced arthritis.

  2020cites this paper
• Hydro-Ethanolic Extract of Portulaca Oleracea Ameliorates Total and Differential WBC, Lung Pathology and Oxidative Biomarkers in Asthmatic Rats

  2019cites this paper
• Current Controversies in Chronic Obstructive Pulmonary Disease. A Report from the Global Initiative for Chronic Obstructive Lung Disease Scientific Committee

  2019cites this paper
• Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease

  2018cites this paper
• Cocoa Pod Husk Pectin Intended as a Pharmaceutical Excipient Has No Adverse Effects on Haematological Parameters in Sprague Dawley Rats

  2018cites this paper
• Biologic Drugs: A New Target Therapy in COPD?

  2018cites this paper
• The Effects of Allium Cepa Extract on Tracheal Responsiveness, Lung Inflammatory Cells and Phospholipase A2 Level in Asthmatic Rats.

  2018cites this paper
• Endobronchial biopsy in the final diagnosis of chronic obstructive pulmonary disease and asthma: a clinicopathological study

  2018cites this paper
• Chronic obstructive pulmonary disease (COPD) : from biomarkers to clinical phenotypes

  2018cites this paper
• Oxidative, inflammatory, genetic, and epigenetic biomarkers associated with chronic obstructive pulmonary disorder

  2018cites this paper
• Smoking-Related Lung Diseases

  2017cites this paper
• Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox

  2017cites this paper
• Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression

  2017cites this paper
• 2 The Importance of Chronic Bronchitis in Chronic Obstructive Pulmonary Disease

  2017cites this paper
• Peripheral eosinophil count as a biomarker for the management of COPD: not there yet

  2017cites this paper
• Eosinophils in COPD: just another biomarker?

  2017cites this paper
• The Relationship between Airway Inflammation and Exacerbation in Chronic Obstructive Pulmonary Disease

  2017cites this paper
• The effect of hydro-ethanolic extract of Curcuma longa rhizome and curcumin on total and differential WBC and serum oxidant, antioxidant biomarkers in rat model of asthma

  2017cites this paper
• Blood Count of Eosinophil Polymorphonuclear Leucocytes and Bronchial Hyperreactivity in Chronic Obstructive Pulmonary Disease

  2017cites this paper
• Albuterol inhalation increases FeNO level in steroid‐naive asthmatics but not COPD patients with reversibility

  2017cites this paper
• Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD

  2017cites this paper
• Pathogenesis of COPD

  2017cites this paper
• A statistical framework for modeling asthma and COPD biological heterogeneity, and a novel variable selection method for model-based clustering

  2016cites this paper
• Cigarette Smoke-Induced Pulmonary Inflammation and Autophagy Are Attenuated in Ephx2-Deficient Mice

  2016cites this paper
• Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.

  2016cites this paper
• Rôle des cellules Club et de CCSP dans la Bronchopneumopathie Chronique Obstructive (BPCO)

  2016cites this paper
• Mitochondrial transfer from induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial and smooth muscle cells attenuates oxidative stress-induced injury

  2016cites this paper
• Ion Channels and Transporters in Lung Function and Disease Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice

  2016cites this paper
• Nontypeable Haemophilus influenzae-induced inflammation, corticosteroids unresponsiveness and functional polarisation in COPD alveolar macrophages

  2016cites this paper
• The Isosteroid Alkaloid Imperialine from Bulbs of Fritillaria cirrhosa Mitigates Pulmonary Functional and Structural Impairment and Suppresses Inflammatory Response in a COPD-Like Rat Model

  2016cites this paper
• Role of Eosinophil Granulocytes in Allergic Airway Inflammation Endotypes

  2016cites this paper
• Extra-esophageal gastroesophageal reflux disease and asthma: understanding this interplay

  2015cites this paper
• Estudo das fibras constituintes da matriz extracelular e da expressão de metaloproteases durante o desenvolvimento do enfisema pulmonar induzido por elastase em camundongos

  2015cites this paper
• bronchial vasculature of sheep Distribution of blood flow and neutrophil kinetics in

  2015cites this paper
• Prostaglandin E2 Regulates Neutrophil Survival Via EP2/PKA/NR4A2 Signalling in the Context of COPD

  2015cites this paper
• Airway Inflammation inCOPDAssessed bySputum Levels oflnterleukin-8*

  2015cites this paper
• inflammation in patients with COPD Effect of incremental exercise on airway and systemic

  2015cites this paper
• Serum testosterone levels in male COPD patients.

  2015cites this paper
• FARMACEUTSKO-BIOKEMIJSKI FAKULTET

  2015influential citation
• Azithromycin Attenuates Pulmonary Inflammation and Emphysema in Smoking-Induced COPD Model in Rats

  2015cites this paper
• Role of CARM1 in regulation of alveolar epithelial senescence and emphysema susceptibility

  2015cites this paper
• IL-8 Gene Variants are Associated with Lung Function Decline and Multidimensional BODE Index in COPD Patients But Not with Disease Susceptibility: A Validation Study

  2015cites this paper
• Estudo de um modelo experimental para o desenvolvimento de enfisema pulmonar induzido por elastase e fumo em camundongos

  2015cites this paper
• Extracellular Matrix Specification of Regenerative Cells in the Adult Lung

  2015cites this paper
• Comparison of the Structural and Inflammatory Features of COPD and Asthma

  2015cites this paper
• Pharmacological targeting of neutrophilic airway inflammation in COPD

  2015influential citation
• Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis.

  2014cites this paper
• Exhaled Nitric Oxide Predicts Eosinophilic Airway Inflammation in COPD

  2014cites this paper
• Biochemical and Pathological Studies on Peroxidases –An Updated Review

  2014cites this paper
• Implementing lessons learned from previous bronchial biopsy trials in a new randomized controlled COPD biopsy trial with roflumilast

  2014cites this paper
• Chronic obstructive pulmonary disease.

  2014cites this paper
• Asthma and COPD – Overlapping Disorders or Distinct Processes?

  2014cites this paper
• Experimental study for the mechanism of gastroesophageal-reflux-associated asthma.

  2014cites this paper
• Induction of the Neutrophil Migration in Normal Subjects due to Asthmatic Bronchoalveolar Lavage Fluid (BALF)

  2014cites this paper
• New Aspects of Alveolar Adaptive Immune Responses in COPD

  2013influential citation
• Phenotyping the heterogeneity of chronic obstructive pulmonary disease.

  2013cites this paper
• Cellular Basis of Bronchial Inflammation in Chronic Obstructive Pulmonary Disease(COPD)

  2013cites this paper
• Eosinophils in Fungus-Associated Allergic Pulmonary Disease

  2013cites this paper
• The effects of cigarette smoke on lipopolysaccharide-mediated responses in airway epithelial cells

  2013cites this paper
• Bronchial Challenges in Airways Disease

  2013cites this paper
• Role of Active Principles of Podophyllum hexandrum in Amelioration of Radiation Mediated Lung Injuries by Reactive Oxygen/Nitrogen Species Reduction

  2013cites this paper
• Effect of incremental exercise on airway and systemic inflammation in patients with COPD.

  2012cites this paper
• The use of biomarkers to explore inflammation and phenotypes during exacerbations of chronic obstructive pulmonary disease

  2012cites this paper
• Effect of Bronchial Colonisation on Airway and Systemic Inflammation in Stable COPD

  2012cites this paper
• Dual Role of Toll-Like Receptors in Asthma and Chronic Obstructive Pulmonary Disease

  2012cites this paper
• The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: assessment of eosinophil degranulation ex vivo and in models of human disease.

  2012cites this paper
• Inhalation of LPS induces inflammatory airway responses mimicking characteristics of chronic obstructive pulmonary disease

  2012cites this paper
• Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD.

  2012cites this paper
• Non-invasive biomarkers of oxidative stress and cell defence in COPD and asthma : specific emphasis on smoking cessation

  2012cites this paper
• Long-acting β2 agonists and corticosteroids restore the reduction of histone deacetylase activity and inhibit H2O2-induced mediator release from alveolar macrophages.

  2012cites this paper
• Respiratory muscle assessment in acute exacerbation of chronic obstructive pulmonary disease and its role as a potential biomarker.

  2012cites this paper
• Chronic bronchitis: a retrospective clinicopathologic study of 25 cases.

  2012cites this paper