Research gaps on methadone harms and comparative harms: findings from a review of the evidence for an American Pain Society and College on Problems of Drug Dependence clinical practice guideline.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Pain

• Publication date

  2014-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jpain.2014.01.496PMID 24685460
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Methadone safety: a clinical practice guideline from the American Pain Society and College on Problems of Drug Dependence, in collaboration with the Heart Rhythm Society.

  2014cited by this paper
• Methadone overdose and cardiac arrhythmia potential: findings from a review of the evidence for an American Pain Society and College on Problems of Drug Dependence clinical practice guideline.

  2014cited by this paper
• Systematic evidence review on methadone harms and comparative harms

  2014cited by this paper
• Vital signs: risk for overdose from methadone used for pain relief - United States, 1999-2010.

  2012cited by this paper
• Buprenorphine versus methadone in pregnant opioid-dependent women: a prospective multicenter study

  2011cited by this paper
• Methadone maintenance, QTc and torsade de pointes: who needs an electrocardiogram and what is the prevalence of QTc prolongation?

  2011cited by this paper
• Morphine to Methadone Conversion: An Interpretation of Published Data

  2011cited by this paper
• Comparative mortality among Department of Veterans Affairs patients prescribed methadone or long‐acting morphine for chronic pain

  2011cited by this paper
• The Source of Methadone in Overdose Deaths in Western Virginia in 2004

  2011cited by this paper
• Risk of drug-related mortality during periods of transition in methadone maintenance treatment: a cohort study.

  2011cited by this paper
• Early switching from morphine to methadone is not improved by acetaminophen in the analgesia of oncologic patients: a prospective, randomized, double-blind, placebo-controlled study

  2010cited by this paper
• Maternal methadone dose during pregnancy and infant clinical outcome.

  2010cited by this paper
• AHRQ series paper 5: grading the strength of a body of evidence when comparing medical interventions--agency for healthcare research and quality and the effective health-care program.

  2010cited by this paper
• Neonatal abstinence syndrome after methadone or buprenorphine exposure.

  2010cited by this paper
• The Effect of Oral Methadone on the QTc Interval in Advanced Cancer Patients: A Prospective Pilot Study

  2010cited by this paper
• Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints.

  2010cited by this paper
• Opioid Maintenance Treatment during Pregnancy: Occurrence and Severity of Neonatal Abstinence Syndrome

  2009cited by this paper
• Prevalence of long QTc interval in methadone maintenance patients.

  2009cited by this paper
• Prevalence and clinical relevance of corrected QT interval prolongation during methadone and buprenorphine treatment: a mortality assessment study.

  2009cited by this paper
• Comparing overdose mortality associated with methadone and buprenorphine treatment.

  2009cited by this paper
• First Do No Harm Reduction?

  2009cited by this paper
• Electrocardiographic Effects of Lofexidine and Methadone Coadministration: Secondary Findings from a Safety Study

  2009cited by this paper
• Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence.

  2009cited by this paper
• A comparison of drug overdose deaths involving methadone and other opioid analgesics in West Virginia.

  2009cited by this paper
• Substance Abuse Treatment, Prevention, and Policy Memory Function in Opioid-dependent Patients Treated with Methadone or Buprenorphine along with Benzodiazepine: Longitudinal Change in Comparison to Healthy Individuals

  2009cited by this paper
• Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain.

  2009cited by this paper
• Factors associated with mortality in Scottish patients receiving methadone in primary care: retrospective cohort study

  2009cited by this paper
• Hypogonadism in men receiving methadone and buprenorphine maintenance treatment.

  2009cited by this paper
• Maternal methadone use in pregnancy: factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources

  2009cited by this paper
• Acoustic cry characteristics of infants exposed to methadone during pregnancy

  2009cited by this paper
• Subjective daytime sleepiness and daytime function in patients on stable methadone maintenance treatment: possible mechanisms.

  2008cited by this paper
• Sustained‐release oral morphine versus transdermal fentanyl and oral methadone in cancer pain management

  2008cited by this paper
• Prospective randomised comparative study of the effect of buprenorphine, methadone and heroin on the course of pregnancy, birthweight of newborns, early postpartum adaptation and course of the neonatal abstinence syndrome (NAS) in women followed up in the outpatient department.

  2008cited by this paper
• Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series.

  2008cited by this paper
• A community-based evaluation of sudden death associated with therapeutic levels of methadone.

  2008cited by this paper
• Electrocardiogram Characteristics of Methadone and Buprenorphine Maintained Subjects

  2008cited by this paper
• Sleep-disordered breathing and chronic opioid therapy.

  2008cited by this paper
• Heterogeneous Impact of Methadone on the QTc Interval: What Are the Practical Implications?

  2008cited by this paper
• Erectile dysfunction in men receiving methadone and buprenorphine maintenance treatment.

  2008cited by this paper
• Increases in poisoning and methadone-related deaths: United States, 1999-2005

  2008cited by this paper
• Patterns of abuse among unintentional pharmaceutical overdose fatalities.

  2008cited by this paper
• Rates of Adverse Events of Long-Acting Opioids in a State Medicaid Program

  2007cited by this paper
• QT-interval effects of methadone, levomethadyl, and buprenorphine in a randomized trial.

  2007cited by this paper
• Corrected-QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross-sectional study.

  2007cited by this paper
• Syncope and QT prolongation among patients treated with methadone for heroin dependence in the city of Copenhagen

  2007cited by this paper
• Effect of Chronic Maternal Methadone Therapy on Intrapartum Fetal Heart Rate Patterns

  2006cited by this paper
• Opioid analgesics and rates of fatal drug poisoning in the United States.

  2006cited by this paper
• Methadone versus buprenorphine in pregnant addicts: a double-blind, double-dummy comparison study.

  2006cited by this paper
• Increasing deaths from opioid analgesics in the United States

  2006cited by this paper
• Opioid analgesic involvement in drug abuse deaths in American metropolitan areas.

  2006cited by this paper
• Guidelines: Report From an American College of Chest Physicians Task Force Grading Strength of Recommendations and Quality of Evidence in Clinical

  2006cited by this paper
• Grading strength of recommendations and quality of evidence in clinical guidelines: report from an american college of chest physicians task force.

  2006cited by this paper
• Neuropsychological functioning in opiate-dependent subjects receiving and following methadone maintenance treatment.

  2006cited by this paper
• Methadone-associated Torsades de Pointes (polymorphic ventricular tachycardia) in opioid-dependent patients.

  2006cited by this paper
• Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors.

  2006cited by this paper
• Testing positive for methadone and either a tricyclic antidepressant or a benzodiazepine is associated with an accidental overdose death: analysis of medical examiner data.

  2006cited by this paper
• Fatal Poisoning in Methadone and Buprenorphine Treated Patients - Are there Differences?

  2006cited by this paper
• Prospective multicenter observational study of 260 infants born to 259 opiate-dependent mothers on methadone or high-dose buprenophine substitution.

  2006cited by this paper
• Effects of Methadone on QT‐Interval Dispersion

  2005cited by this paper
• Unintentional methadone-related overdose death in New Mexico (USA) and implications for surveillance, 1998-2002.

  2005cited by this paper
• Central sleep apnea in stable methadone maintenance treatment patients.

  2005cited by this paper
• Measurement of QTc in patients receiving chronic methadone therapy.

  2005cited by this paper
• Opioid abuse and cognitive performance.

  2005cited by this paper
• Methadone Maintenance and Male Sexual Dysfunction

  2005cited by this paper
• Buprenorphine versus methadone in the treatment of pregnant opioid-dependent patients: effects on the neonatal abstinence syndrome.

  2005cited by this paper
• Impact of methadone treatment on cardiac repolarization and conduction in opioid users.

  2005cited by this paper
• Ventilatory responses to hypoxia and hypercapnia in stable methadone maintenance treatment patients.

  2005cited by this paper
• The effect of methadone treatment on the quantity and quality of human fetal movement.

  2004cited by this paper
• A critical review of the causes of death among post-mortem toxicological investigations: analysis of 34 buprenorphine-associated and 35 methadone-associated deaths.

  2004cited by this paper
• Overdose deaths attributed to methadone and heroin in New York City, 1990-1998.

  2004cited by this paper
• Methadone versus morphine as a first-line strong opioid for cancer pain: a randomized, double-blind study.

  2004cited by this paper
• Oral methadone for cancer pain: no indication of Q-T interval prolongation or torsades de pointes.

  2004cited by this paper
• Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence.

  2003cited by this paper
• Dose‐Related Effects of Methadone on QT Prolongation in a Series of Patients with Torsade de Pointes

  2003cited by this paper
• Buprenorphine versus methadone maintenance therapy: a randomized double-blind trial with 405 opioid-dependent patients.

  2003cited by this paper
• Methadone-Related Deaths Associated with Faulty Induction Procedures

  2003cited by this paper
• Methadone-related deaths in Hennepin County, Minnesota: 1992-2002.

  2003cited by this paper
• Increase in deaths due to methadone in North Carolina.

  2003cited by this paper
• The role of methadone in drug-related deaths in the west of Scotland.

  2003cited by this paper
• Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review.

  2003cited by this paper
• A randomized, double-blind, placebo-controlled safety study of high-dose dextromethorphan in methadone-maintained male inpatients.

  2002cited by this paper
• Methadone‐related deaths in Western Australia 1993–99

  2002cited by this paper
• An increase in overdose mortality during the first 2 weeks after entering or re-entering methadone treatment in Amsterdam.

  2002cited by this paper
• Methadone-related deaths and mortality rate during induction into methadone maintenance, New South Wales, 1996.

  2002cited by this paper
• Effects of methadone on cognition, mood and craving in detoxifying opiate addicts: a dose-response study

  2001cited by this paper
• Hyperalgesic responses in methadone maintenance patients

  2001cited by this paper
• Opiate-related deaths in Dublin

  2001cited by this paper
• Cognitive-Motor Performance of Methadone-Maintained Patients

  2000cited by this paper
• Methadone, methadone treatment and non-fatal overdose.

  2000cited by this paper
• Cognitive impairment among methadone maintenance patients.

  2000cited by this paper
• Deaths in methadone maintenance treatment in New South Wales, Australia 1990-1995.

  2000cited by this paper
• A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence.

  2000cited by this paper
• NIH Consensus Panel Recommends Expanding Access to and Improving Methadone Treatment Programs for Heroin Addiction

  1999cited by this paper
• Comparison of methadone and slow-release morphine maintenance in pregnant addicts.

  1999cited by this paper
• Dose-effect relationship between overdose mortality and prescribed methadone dosage in low-threshold maintenance programs.

  1999cited by this paper
• First Do No Harm: Adverse Effects of Grouping Deviant Youth for Skills Training

  1999cited by this paper
• Methadone maintenance in pregnancy: a reappraisal.

  1998cited by this paper
• Morphine versus methadone in the pain treatment of advanced-cancer patients followed up at home.

  1998cited by this paper
• The effect of fluconazole on the clinical pharmacokinetics of methadone

  1998cited by this paper
• Methadone‐related overdose deaths in South Australia, 1984‐1994: How safe is methadone prescribing?

  1997cited by this paper

• Does polypharmacy increase opioid sensitivity in cats?

  2025cites this paper
• QTc prolongation and torsades de pointes (TdP) in individuals undergoing methadone maintenance treatment (MMT): A systematic review and meta-analysis

  2025cites this paper
• Piloting a Hospital-Based Rapid Methadone Initiation Protocol for Fentanyl

  2024cites this paper
• The remaining role and feasibility of detoxification in opioid addiction after 30 years of medication for opioid use disorder: A systematic review

  2022cites this paper
• QT length during methadone maintenance treatment: Gene x dose interaction

  2019cites this paper
• Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment

  2019cites this paper
• Identifying Research Gaps and Prioritizing Psychological Health Evidence Synthesis Needs

  2019cites this paper
• Perceived barriers to methadone maintenance treatment among Iranian opioid users

  2018cites this paper
• Methadone and Corrected QT Prolongation in Pain and Palliative Care Patients: A Case–Control Study

  2017cites this paper
• Opioid tapering in patients with prescription opioid use disorder: A retrospective study

  2017cites this paper
• Contingency Management Effect on Cocaine Use While Using Methadone

  2017cites this paper
• Responsible, Safe, and Effective Prescription of Opioids for Chronic Non-Cancer Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

  2017cites this paper
• Using the Surprise Question To Identify Those with Unmet Palliative Care Needs in Emergency and Inpatient Settings: What Do Clinicians Think?

  2017cites this paper
• Methadone Treatment of Opiate Addiction: A Systematic Review of Comparative Studies.

  2017cites this paper
• Economic vulnerability of methadone maintenance patients: Implications for policies on co-payment services.

  2016cites this paper
• Current State of Opioid Therapy and Abuse

  2016cites this paper
• Risk-factors for methadone-specific deaths in Scotland’s methadone-prescription clients between 2009 and 2013*

  2016cites this paper
• American Society of Addiction Medicine (ASAM) National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use

  2015cites this paper
• Drug-related deaths between 2002 and 2013 with accent to methadone and benzodiazepines.

  2015cites this paper
• Treatment readiness, attitudes toward, and experiences with methadone and buprenorphine maintenance therapy among people who inject drugs in Malaysia.

  2015cites this paper
• Pain Among High-Risk Patients on Methadone Maintenance Treatment.

  2015cites this paper
• Predictors of Opioid-Related Death During Methadone Therapy.

  2015cites this paper
• of Substance Abuse Treatment Treatment Readiness , Attitudes Toward , and ExperienceswithMethadone and Buprenorphine Maintenance Therapy Among People Who Inject Drugs in Malaysia

  2015cites this paper
• American Pain Society's New Clinical Practice Guidelines Promote Safer Use of Methadone and Highlight Research Gaps

  2014cites this paper
• Considerations in methadone dosing for opioid addiction

  2014cites this paper
• UST Research Online UST Research Online

  year unknowncites this paper