Adenosine Receptor-Mediated Cardioprotection

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Cardiovascular Pharmacology and Therapeutics

• Publication date

  2012-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/1074248410396877PMID 21335481
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Stimulation of adenosine A2B receptors induces interleukin‐6 secretion in cardiac fibroblasts via the PKC‐δ–P38 signalling pathway

  2010cited by this paper
• A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells.

  2010cited by this paper
• Cooperative Cardioprotection Through Adenosine A1 and A2A Receptor Agonism in Ischemia-Reperfused Isolated Mouse Heart

  2010cited by this paper
• Evidence that the acute phase of ischemic preconditioning does not require signaling by the A 2B adenosine receptor.

  2010cited by this paper
• Differential effects of adenosine A2a and A2b receptors on cardiac contractility.

  2010cited by this paper
• Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts.

  2010cited by this paper
• Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts.

  2009cited by this paper
• Reduction in myocardial infarct size at 48 hours after brief intravenous infusion of ATL-146e, a highly selective adenosine A2A receptor agonist.

  2009cited by this paper
• Cardioprotection Induced by Adenosine A1 Receptor Agonists in a Cardiac Cell Ischemia Model Involves Cooperative Activation of Adenosine A2A and A2B Receptors by Endogenous Adenosine

  2009cited by this paper
• Regulation of ATP-sensitive K+ channels by caveolin-enriched microdomains in cardiac myocytes.

  2009cited by this paper
• Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse.

  2009cited by this paper
• Adenosine A(1) receptors selectively target protein kinase C isoforms to the caveolin-rich plasma membrane in cardiac myocytes.

  2009cited by this paper
• Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart

  2008cited by this paper
• The A3 Adenosine Receptor Agonist CP-532,903 [N6-(2,5-Dichlorobenzyl)-3′-aminoadenosine-5′-N-methylcarboxamide] Protects against Myocardial Ischemia/Reperfusion Injury via the Sarcolemmal ATP-Sensitive Potassium Channel

  2008cited by this paper
• Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation.

  2008cited by this paper
• Oxidative stress and adenosine A1 receptor activation differentially modulate subcellular cardiomyocyte MAPKs.

  2008cited by this paper
• Loss of Myocardial Ischemic Postconditioning in Adenosine A1 and Bradykinin B2 Receptors Gene Knockout Mice

  2008cited by this paper
• Infarct limitation by a protein kinase G activator at reperfusion in rabbit hearts is dependent on sensitizing the heart to A2b agonists by protein kinase C.

  2008influential reference
• Heterodimers and receptor mosaics of different types of G-protein-coupled receptors.

  2008cited by this paper
• Activation of the A3 Adenosine Receptor Suppresses Superoxide Production and Chemotaxis of Mouse Bone Marrow Neutrophils

  2008cited by this paper
• Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A2B Adenosine Receptors

  2007cited by this paper
• Ischemic Postconditioning Reduces Infarct Size by Activation of A1 Receptors and K+ATP Channels in Both Normal and Hypercholesterolemic Rabbits

  2007cited by this paper
• Targeted deletion of A2A adenosine receptors attenuates the protective effects of myocardial postconditioning.

  2007cited by this paper
• Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.

  2007cited by this paper
• The A2a/A2b receptor antagonist ZM-241385 blocks the cardioprotective effect of adenosine agonist pretreatment in in vivo rat myocardium.

  2007cited by this paper
• Isolation and characterization of coronary endothelial and smooth muscle cells from A1 adenosine receptor-knockout mice.

  2006cited by this paper
• Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.

  2006cited by this paper
• Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning.

  2006cited by this paper
• Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle.

  2006cited by this paper
• N6-(3-Iodobenzyl)-adenosine-5′-N-methylcarboxamide Confers Cardioprotection at Reperfusion by Inhibiting Mitochondrial Permeability Transition Pore Opening via Glycogen Synthase Kinase 3β

  2006cited by this paper
• Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.

  2006cited by this paper
• Cl-IB-MECA [2-Chloro-N6-(3-iodobenzyl)adenosine-5′-N-methylcarboxamide] Reduces Ischemia/Reperfusion Injury in Mice by Activating the A Adenosine Receptor

  2006cited by this paper
• N 6-( 3-Iodobenzyl )-adenosine-5-N-methylcarboxamide Confers Cardioprotection at Reperfusion by Inhibiting Mitochondrial Permeability Transition Pore Opening via Glycogen Synthase Kinase 3

  2006cited by this paper
• Myocardial Infarct–Sparing Effect of Adenosine A2A Receptor Activation Is due to Its Action on CD4+ T Lymphocytes

  2006cited by this paper
• Delayed adenosine A1 receptor preconditioning in rat myocardium is MAPK dependent but iNOS independent.

  2005cited by this paper
• Sustained Cardioprotection Afforded by A2A Adenosine Receptor Stimulation After 72 Hours of Myocardial Reperfusion

  2005cited by this paper
• Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance

  2005cited by this paper
• Infarct-Sparing Effect of A2A-Adenosine Receptor Activation Is Due Primarily to Its Action on Lymphocytes

  2005cited by this paper
• Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.

  2005cited by this paper
• Pivotal role of NOX‐2‐containing NADPH oxidase in early ischemic preconditioning

  2005cited by this paper
• Adenosine triggers preconditioning through MEK/ERK1/2 signalling pathway during hypoxia/reoxygenation in neonatal rat cardiomyocytes.

  2005influential reference
• Acute adenosine preconditioning is mediated by p38 MAPK activation in discrete subcellular compartments.

  2005influential reference
• Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium.

  2005cited by this paper
• In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.

  2005influential reference
• NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.

  2004cited by this paper
• The p38 MAPK Inhibitor SB203580 Blocks Adenosine A1 Receptor-Induced Attenuation of In Vivo Myocardial Stunning

  2004cited by this paper
• Comparison of Three Different A1 Adenosine Receptor Antagonists on Infarct Size and Multiple Cycle Ischemic Preconditioning in Anesthetized Dogs

  2004influential reference
• Cardioprotective effects of adenosine A1 and A 3 receptor activation during hypoxia in isolated rat cardiac myocytes

  2004cited by this paper
• Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes.

  2004influential reference
• Functional effects of enhancing or silencing adenosine A2b receptors in cardiac fibroblasts.

  2004cited by this paper
• Post-Ischemic Cardioprotection by A2A Adenosine Receptors: Dependent of Phosphatidylinositol 3-Kinase Pathway

  2004cited by this paper
• Limitation of Myocardial Reperfusion Injury by AMP579, an Adenosine A1/A2A Receptor Agonist: Role of A2A Receptor and Erk1/2

  2003cited by this paper
• The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38.

  2003cited by this paper
• Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.

  2003cited by this paper
• Protection from myocardial stunning by ischaemia and hypoxia with the adenosine A3 receptor agonist, IB-MECA.

  2003cited by this paper
• A3 adenosine receptor agonist IB-MECA reduces myocardial ischemia-reperfusion injury in dogs.

  2003cited by this paper
• Adenosine A2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells

  2003cited by this paper
• Modulation of protein phosphatase 2a by adenosine A1 receptors in cardiomyocytes: role for p38 MAPK.

  2003cited by this paper
• Receptor and non-receptor-dependent mechanisms of cardioprotection with adenosine.

  2003cited by this paper
• Medicinal chemistry of adenosine A3 receptor ligands.

  2003cited by this paper
• Novel N6-substituted adenosine 5'-N-methyluronamides with high selectivity for human adenosine A3 receptors reduce ischemic myocardial injury.

  2003cited by this paper
• Adenosine-Mediated Cardioprotection in Ischemic-Reperfused Mouse Heart

  2002cited by this paper
• Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization.

  2002cited by this paper
• Mitochondrial K(ATP) channels: role in cardioprotection.

  2002cited by this paper
• Adenosine A(1) receptor mediates late preconditioning via activation of PKC-delta signaling pathway.

  2002cited by this paper
• Adenosine A(3) receptor activation protects the myocardium from reperfusion/reoxygenation injury.

  2002cited by this paper
• Adenosine A1 receptor mediates late preconditioning via activation of PKC-δ signaling pathway

  2002cited by this paper
• Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

  2001cited by this paper
• Acetylcholine, Bradykinin, Opioids, and Phenylephrine, but not Adenosine, Trigger Preconditioning by Generating Free Radicals and Opening Mitochondrial KATP Channels

  2001cited by this paper
• Targeted deletion of A(3) adenosine receptors improves tolerance to ischemia-reperfusion injury in mouse myocardium.

  2001cited by this paper
• Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery

  2001cited by this paper
• Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium.

  2001cited by this paper
• Targeted deletion of the A3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning.

  2001cited by this paper
• Disruption of the A3 Adenosine Receptor Gene in Mice and Its Effect on Stimulated Inflammatory Cells*

  2000cited by this paper
• Adenosine A2A and A2B receptors mediated nitric oxide production in coronary artery endothelial cells

  2000cited by this paper
• Role for PKC in the adenosine-induced decrease in shortening velocity of rat ventricular myocytes.

  2000cited by this paper
• Roles of mitochondrial ATP-sensitive K channels and PKC in anti-infarct tolerance afforded by adenosine A1 receptor activation.

  2000cited by this paper
• Adenosine A(2a)-receptor activation increases contractility in isolated perfused hearts.

  2000cited by this paper
• Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells.

  2000cited by this paper
• Adenosine A(2A) and A(2B) receptors mediated nitric oxide production in coronary artery endothelial cells.

  2000cited by this paper
• Adenosine A1 Agonist at Reperfusion Trial (AART): Results of a Three-Center, Blinded, Randomized, Controlled Experimental Infarct Study

  2000cited by this paper
• Adenosine A2A and A2B receptors in cultured human and porcine coronary artery endothelial cells

  2000cited by this paper
• Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2.

  2000cited by this paper
• Comparative study of AMP579 and adenosine in inhibition of neutrophil-mediated vascular and myocardial injury during 24 h of reperfusion.

  2000cited by this paper
• Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms.

  1999cited by this paper
• Adenosine-induced activation of ATP-sensitive K+ channels in excised membrane patches is mediated by PKC.

  1999cited by this paper
• The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion

  1999cited by this paper
• Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies.

  1999cited by this paper
• Cardiovascular pharmacology of the adenosine A1/A2-receptor agonist AMP 579: coronary hemodynamic and cardioprotective effects in the canine myocardium.

  1999cited by this paper
• Adenosine A3-receptor stimulation attenuates postischemic dysfunction through KATP channels.

  1999cited by this paper
• The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig.

  1999cited by this paper
• Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms.

  1999cited by this paper
• A3 adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury.

  1999cited by this paper
• Role of A2A receptor in the modulation of myocardial reperfusion damage.

  1999cited by this paper
• Modulation of Mitochondrial ATP-Dependent K+ Channels by Protein Kinase C

  1998cited by this paper
• Immunological characterization of adenosine A2A receptors in human and porcine cardiovascular tissues.

  1998cited by this paper
• Modulation of mitochondrial ATP-dependent K+ channels by protein kinase C.

  1998cited by this paper
• Protein kinase C-dependent activation of KATP channel enhances adenosine-induced cardioprotection.

  1998cited by this paper
• KATP‐channel activation: effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1‐receptor stimulation

  1998cited by this paper
• Cardioprotective effects of the novel adenosine A1/A2 receptor agonist AMP 579 in a porcine model of myocardial infarction.

  1998cited by this paper

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