Programmed Cell Death

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Methods in Molecular Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-1-4939-3581-9
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Cell Viability Assays

  2016cited by this paper
• Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain

  2015cited by this paper
• Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

  2015cited by this paper
• Bh3 induced conformational changes in Bcl‐Xl revealed by crystal structure and comparative analysis

  2015cited by this paper
• A Practical Guide for the Treatment of Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)

  2014influential reference
• Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.

  2014cited by this paper
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.

  2014cited by this paper
• Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).

  2014cited by this paper
• The Functional Differences between Pro-survival and Pro-apoptotic B Cell Lymphoma 2 (Bcl-2) Proteins Depend on Structural Differences in Their Bcl-2 Homology 3 (BH3) Domains*

  2014cited by this paper
• Causes and pathophysiology of heart failure with preserved ejection fraction.

  2014cited by this paper
• Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.

  2014cited by this paper
• Animal models of human disease: challenges in enabling translation.

  2014cited by this paper
• The DNA-binding domain mediates both nuclear and cytosolic functions of p53

  2014cited by this paper
• CREB-binding protein (CBP) regulates beta-adrenoceptor (beta-AR) - mediated apoptosis

  2013cited by this paper
• Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.

  2013cited by this paper
• Recent advances in the epidemiology, pathogenesis and prognosis of acute heart failure and cardiomyopathy in Africa

  2013cited by this paper
• p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress*

  2013cited by this paper
• BID-induced structural changes in BAK promote apoptosis

  2013cited by this paper
• Developmentally programmed cell death in Drosophila.

  2013cited by this paper
• The role of the acidity of N-heteroaryl sulfonamides as inhibitors of bcl-2 family protein-protein interactions.

  2013cited by this paper
• Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity.

  2013cited by this paper
• ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

  2013cited by this paper
• Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.

  2013cited by this paper
• NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL.

  2012cited by this paper
• Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists.

  2012cited by this paper
• Identification of a phenylacylsulfonamide series of dual Bcl-2/Bcl-xL antagonists.

  2012cited by this paper
• [Chronic heart failure: progress in diagnosis and treatment. Topics: I. Progress in epidemiology and fundamental research; 2. Molecular mechanisms of chronic heart failure].

  2012cited by this paper
• Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.

  2012cited by this paper
• Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold.

  2012cited by this paper
• PUMA Binding Induces Partial Unfolding within BCL-xL to Disrupt p53 Binding and Promote Apoptosis

  2012cited by this paper
• Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA

  2012cited by this paper
• Power tools for gene expression and clonal analysis in Drosophila

  2011cited by this paper
• Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity.

  2011cited by this paper
• Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.

  2011cited by this paper
• Mutation to Bax beyond the BH3 Domain Disrupts Interactions with Pro-survival Proteins and Promotes Apoptosis*

  2011cited by this paper
• Animal Models of Cardiovascular Diseases

  2011cited by this paper
• Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL

  2011cited by this paper
• Discovery and molecular characterization of a Bcl-2–regulated cell death pathway in schistosomes

  2011cited by this paper
• The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro

  2011cited by this paper
• Dual roles of Drosophila p53 in cell death and cell differentiation

  2009cited by this paper
• Regulation of apoptosis in Drosophila

  2008cited by this paper
• Regulation of the Drosophila Apoptosome through Feedback Inhibition

  2008cited by this paper
• H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart.

  2007cited by this paper
• Mitochondrial disruption in Drosophila apoptosis.

  2007cited by this paper
• Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer.

  2006cited by this paper
• Lack of involvement of mitochondrial factors in caspase activation in a Drosophila cell-free system

  2006cited by this paper
• Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster.

  2006cited by this paper
• Discrete pulses of molting hormone, 20‐hydroxyecdysone, during late larval development of Drosophila melanogaster: Correlations with changes in gene activity

  2006cited by this paper
• Hid can induce, but is not required for autophagy in polyploid larval Drosophila tissues.

  2005cited by this paper
• Spatiotemporal Rescue of Memory Dysfunction in Drosophila

  2003cited by this paper
• Distinct pathways mediate UV-induced apoptosis in Drosophila embryos.

  2003cited by this paper
• The glial cell undergoes apoptosis in the microchaete lineage of Drosophila

  2003cited by this paper
• The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

  2002cited by this paper
• Molecular remodelling of dystrophin in patients with end-stage cardiomyopathies and reversal in patients on assistance-device therapy.

  2002cited by this paper
• Drosophila sickle is a novel grim-reaper cell death activator.

  2002cited by this paper
• sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein.

  2002cited by this paper
• The role of cytochrome c in caspase activation in Drosophila melanogaster cells

  2002cited by this paper
• A conditional tissue-specific transgene expression system using inducible GAL4

  2001cited by this paper
• Steroid regulation of programmed cell death during Drosophila development

  2000cited by this paper
• Drosophila p53 binds a damage response element at the reaper locus.

  2000cited by this paper
• A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis.

  2000cited by this paper
• Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.

  1999cited by this paper
• Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis.

  1999cited by this paper
• HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte.

  1998cited by this paper
• grim, a novel cell death gene in Drosophila.

  1996cited by this paper
• Activation of the reaper gene during ectopic cell killing in Drosophila.

  1996cited by this paper
• Genetic control of programmed cell death in Drosophila.

  1994cited by this paper
• Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

  1993cited by this paper
• The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

  1993cited by this paper
• Embryonic head involution and rotation of male terminalia require the Drosophila locus head involution defective.

  1991cited by this paper
• Cell cultures of adult cardiomyocytes as models of the myocardium.

  1986cited by this paper
• Properties of a clonal muscle cell line from rat heart.

  1976cited by this paper
• DYNAMICS OF ACRIDINE ORANGE-CELL INTERACTION. I. INTERRELATIONSHIPS OF ACRIDINE ORANGE PARTICLES AND CYTOPLASMIC REDDENING.

  1963cited by this paper

• Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection

  2026cites this paper
• Green Synthesis of Copper Oxide Nanoparticles Using Camellia sinensis: Anticancer Potential and Apoptotic Mechanism in HT-29 and MCF-7 Cells

  2025cites this paper
• Editorial: Targeting the aging mitochondria: mechanisms, methods, and therapeutic strategies

  2025cites this paper
• COMBINED ANTIFUGAL ACTIVITIES OF ALOE VERA, LIME, AND GARLIC EXTRACTS AGAINST CANDIDA ALBICANS AND MALASSEZIA FURFUR

  2025cites this paper
• Tumor-infiltrating lymphocytes in cancer immunotherapy: from chemotactic recruitment to translational modeling

  2025cites this paper
• Mechanics of oogenesis: Lessons from C. elegans germline cysts.

  2025cites this paper
• Unravelling T cell exhaustion through co‐inhibitory receptors and its transformative role in cancer immunotherapy

  2025influential citation
• Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application

  2025cites this paper
• Mechanisms underlying immunosuppression by regulatory cells

  2024cites this paper
• Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans

  2024cites this paper
• Iron-induced kidney cell damage: insights into molecular mechanisms and potential diagnostic significance of urinary FTL

  2024cites this paper
• Beclin-1: a therapeutic target at the intersection of autophagy, immunotherapy, and cancer treatment

  2024cites this paper
• Emerging role of immunogenic cell death in cancer immunotherapy

  2024cites this paper
• A stepwise-responsive editor integrated with three copper ions for the treatment of oral squamous cell carcinoma

  2024cites this paper
• Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer

  2024cites this paper
• You can’t always get as much iron as you want: how rice plants deal with excess of an essential nutrient

  2024cites this paper
• Cell Death Pathways in Dry Eye Disease: Insights into Ocular Surface Inflammation.

  2024cites this paper
• Dynamic changes in global methylation and plant cell death mechanism in response to NiO nanoparticles

  2023cites this paper
• Transcriptional signatures associated with waterlogging stress responses and aerenchyma formation in barley root tissue

  2023influential citation
• Systematic analysis of the cuprotosis in tumor microenvironment and prognosis of gastric cancer

  2023cites this paper
• Polyethylene nanoplastics cause reproductive toxicity associated with activation of both estrogenic hormone receptor NHR-14 and DNA damage checkpoints in C. elegans.

  2023cites this paper
• Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana

  2023cites this paper
• Arabidopsis cell suspension culture and RNA sequencing reveal regulatory networks underlying plant programmed cell death

  2023cites this paper
• Novel fluorinated pyrazole-based heterocycles scaffold: cytotoxicity, in silico studies and molecular modelling targeting double mutant EGFR ^L858R/T790M as antiproliferative and apoptotic agents

  2023cites this paper
• SUSTAINED ANTICANCER EFFECT BY NARINGIN-LOADED ZINC OXIDE NANOPARTICLES IN HUMAN LUNG ADENOCARCINOMA A549 CELLS

  2023cites this paper
• Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans

  2023cites this paper
• Autophagic and phytochemical aspects of color changes in white petals of snapdragon flower during development and senescence

  2023cites this paper
• The role and implication of autophagy in cholangiocarcinoma

  2023cites this paper
• Menthol induces apoptosis and inhibits proliferation and migration of nonsmall cell lung carcinoma in vitro and in vivo through Akt pathway

  2023cites this paper
• Investigation into the communication between unheated and heat-stressed Caenorhabditis elegans via volatile stress signals

  2023cites this paper
• FGF21 prevents neuronal cell ferroptosis after spinal cord injury by activating the FGFR1/β-Klotho pathway.

  2023cites this paper
• Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

  2023cites this paper
• Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior

  2023cites this paper
• N6-methyladenosine RNA is modified in the rat hippocampus following traumatic brain injury with hypothermia treatment

  2023cites this paper
• A necessary considering factor for breeding: growth-defense tradeoff in plants

  2023cites this paper
• Biochemical and molecular mechanisms of Annona sp. fruits extract in Ehrlich ascites carcinoma-bearing mice

  2023cites this paper
• Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis

  2023cites this paper
• iPCD: A Comprehensive Data Resource of Regulatory Proteins in Programmed Cell Death

  2022cites this paper
• Transcriptional Regulation of Quinoa Seed Quality: Identification of Novel Candidate Genetic Markers for Increased Protein Content

  2022cites this paper
• Investigation of the cell structure and organelles during autolytic PCD of Antirrhinum majus “Legend White” petals

  2022cites this paper
• l-Ascorbic acid sodium salt promotes microspore embryogenesis and chromosome doubling by colchicine in ornamental kale (Brassica oleracea var. acephala)

  2022cites this paper
• PlMYB308 Regulates Flower Senescence by Modulating Ethylene Biosynthesis in Herbaceous Peony

  2022cites this paper
• Targeting Selective Autophagy as a Therapeutic Strategy for Viral Infectious Diseases

  2022cites this paper
• A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in allorecognition in Neurospora crassa

  2022cites this paper
• Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway

  2022cites this paper
• Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization

  2022cites this paper
• Fusarium wilt of banana: sustainable management through deployment of antiapoptotic genes into the susceptible genomes

  2022cites this paper
• Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis

  2022cites this paper
• Maize Endosperm Development: Tissues, Cells, Molecular Regulation and Grain Quality Improvement

  2022influential citation
• Microbial interaction mediated programmed cell death in plants

  2022cites this paper
• Pyroptosis-Related Gene to Construct Prognostic Signature and Explore Immune Microenvironment and Immunotherapy Biomarkers in Bladder Cancer

  2022cites this paper
• Cadmium is detrimental to Caenorhabditis elegans via a network involving circRNA, lncRNA and phosphorylated protein

  2022cites this paper
• A Systematic Review of the Mechanisms Involved in Immune Checkpoint Inhibitors Cardiotoxicity and Challenges to Improve Clinical Safety

  2022cites this paper
• The Two Classes of Ceramide Synthases Play Different Roles in Plant Immunity and Cell Death

  2022cites this paper
• Fate-resolved gene regulatory signatures of individual B lymphocytes in the early stages of Epstein-Barr Virus infection

  2022cites this paper
• Preharvest UV-C Hormesis Induces Key Genes Associated With Homeostasis, Growth and Defense in Lettuce Inoculated With Xanthomonas campestris pv. vitians

  2022cites this paper
• Revealing the Impact of Mitochondrial Fitness During Early Neural Development Using Human Brain Organoids

  2022cites this paper
• Regulation of defective mitochondrial DNA 1 accumulation and transmission in C. elegans by the 2 programmed cell death and aging pathways

  2022cites this paper
• The Ancient Origins of Death Domains Support the ‘Original Sin’ Hypothesis for the Evolution of Programmed Cell Death

  2022cites this paper
• Pyroptosis-Related Signature and Tumor Microenvironment Infiltration Characterization in Head and Neck Squamous Cell Carcinoma

  2022cites this paper
• Long Non-Coding RNAs H19 and HOTAIR Implicated in Intervertebral Disc Degeneration

  2022cites this paper
• Pathophysiology of Hodgkin’s Lymphoma and Role of Immune System

  2022cites this paper
• Caenorhabditis elegans as a model to assess reproductive and developmental toxicity

  2022cites this paper
• Nucleases are upregulated in potato tubers afflicted with zebra chip disease

  2022cites this paper
• Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy

  2022cites this paper
• Specialized endoplasmic reticulum‐derived vesicles in plants: Functional diversity, evolution, and biotechnological exploitation

  2022cites this paper
• Molecular Events Involved in Influenza A Virus-Induced Cell Death

  2022cites this paper
• The Function, Regulation and Mechanism of Programmed Cell Death of Macrophages in Atherosclerosis

  2022cites this paper
• Effects of Flooding and Endogenous Hormone on the Formation of Knee Roots in Taxodium ascendens

  2022cites this paper
• Responses of Bloom-Forming Heterosigma akashiwo to Allelochemical Linoleic Acid: Growth Inhibition, Oxidative Stress and Apoptosis

  2022cites this paper
• Intraocular implants loaded with A3R agonist rescue retinal ganglion cells from ischemic damage.

  2022cites this paper
• : current

  2022cites this paper
• Graphene quantum dots induce cascadic apoptosis via interaction with proteins associated with anti-oxidation after endocytosis by Trypanosoma brucei

  2022cites this paper
• Kinetin induces microtubular breakdown, cell cycle arrest and programmed cell death in tobacco BY-2 cells

  2022cites this paper
• Roles of Glutamate Receptor-Like Channels (GLRs) in Plant Growth and Response to Environmental Stimuli

  2022cites this paper
• A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition

  2022cites this paper
• Application of network pharmacology and molecular docking approach to explore active compounds and potential pharmacological mechanisms of Aconiti Lateralis Radix Praeparata and Lepidii Semen Descurainiae Semen for treatment of heart failure

  2022cites this paper
• Are Viral Infections Key Inducers of Autoimmune Diseases? Focus on Epstein–Barr Virus

  2022cites this paper
• Low-Dose Resveratrol Inhibits RIPK3-Mediated Necroptosis and Delays the Onset of Age-Related Hearing Loss

  2022cites this paper
• Dysregulation of Cytosolic c-di-GMP in Edwardsiella piscicida Promotes Cellular Non-Canonical Ferroptosis

  2022cites this paper
• The Relevance of Programmed Cell Death to Spontaneous Defoliation in Sugarcane Leaf Sheaths

  2022cites this paper
• Interrelation between extracellular vesicles miRNAs with chronic lung diseases

  2022cites this paper
• Molecular mechanisms underlying Warburgia salutaris effects on oxidative stress and apoptotic parameters in Human Hepatoma Cells

  2022cites this paper
• Genome stability in Caenorhabditis elegans

  2021cites this paper
• Exogenous abscisic acid impacts the development of isolated immature endosperm in bread wheat

  2021influential citation
• Epstein-Barr Virus as the Cause of Rheumatoid Arthritis

  2021cites this paper
• Biochemical Characterization of a Novel Redox-Regulated Metacaspase in a Marine Diatom

  2021cites this paper
• Study Anticancer effects of Moringa oleifera Leaf Water Extract on MCF-7 Breast-cancer Cells and Using its Leaves Powder as Food Additive

  2021cites this paper
• The Rapid Cytological Process of Grain Determines Early Maturity in Weedy Rice

  2021cites this paper
• Evolution of haematopoietic cell transplantation for canine blood disorders and a platform for solid organ transplantation

  2021cites this paper
• The Expression Profile of Bcl-2 Protein in Prostate Cancer Patients

  2021cites this paper
• DNA repair, recombination, and damage signaling

  2021influential citation
• Advanced therapeutic modalities in hepatocellular carcinoma: Novel insights

  2021cites this paper
• Transcriptional Regulation and Signaling of Developmental Programmed Cell Death in Plants

  2021cites this paper
• BLMP-1 promotes developmental cell death in C. elegans by timely repression of ced-9/bcl-2 transcription.

  2021cites this paper
• Ceramide Kinase Inhibition Blocks IGF-1-Mediated Survival of Otic Neurosensory Progenitors by Impairing AKT Phosphorylation

  2021cites this paper
• Multiple functions of the vacuole in plant growth and fruit quality

  2021cites this paper
• Brown Algae Phlorotannins: A Marine Alternative to Break the Oxidative Stress, Inflammation and Cancer Network

  2021cites this paper
• Low PDCD4 Expression Is Associated With Poor Prognosis of Colorectal Carcinoma

  2021cites this paper
• Potassium physiology from Archean to Holocene: A higher-plant perspective.

  2021cites this paper