Physical characterization of the herpes simplex virus latency-associated transcript in neurons

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Journal of Virology

• Publication date

  1988-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jvi.62.4.1194-1202.1988PMID 2831380PMCID PMC253127
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Continued expression of a poly(A)+ transcript of herpes simplex virus type 1 in trigeminal ganglia of latently infected mice

  1987cited by this paper
• Hybridization between a repeated region of herpes simplex virus type 1 DNA containing the sequence [GGC]n and heterodisperse cellular DNA and RNA.

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• RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons.

  1987influential reference
• Detection of latency-related viral RNAs in trigeminal ganglia of rabbits latently infected with herpes simplex virus type 1

  1987cited by this paper
• Translational regulation of expression of the bacteriophage T4 lysozyme gene.

  1986cited by this paper
• Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110.

  1986cited by this paper
• Characterization of the IE110 gene of herpes simplex virus type 1.

  1986cited by this paper
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  1986influential reference
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  1985cited by this paper
• Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA.

  1985cited by this paper
• Localization of herpes simplex virus in the trigeminal and olfactory systems of the mouse central nervous system during acute and latent infections by in situ hybridization.

  1984cited by this paper
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  1984cited by this paper
• Herpes simplex virus latency.

  1984cited by this paper
• Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C

  1983cited by this paper
• Detection of HSV-1 genome in central nervous system of latently infected mice

  1983cited by this paper
• A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.

  1982cited by this paper
• Homology between mammalian cell DNA sequences and human herpesvirus genomes detected by a hybridization procedure with high-complexity probe.

  1982cited by this paper
• Homology between murine and human cellular DNA sequences and the terminal repetition of the S component of herpes simplex virus type 1 DNA.

  1982cited by this paper
• Recognition of protein coding regions in DNA sequences.

  1982cited by this paper
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  1981cited by this paper
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  1981cited by this paper
• Sequencing end-labeled DNA with base-specific chemical cleavages.

  1980cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• Latent Herpes Simplex Virus in Spinal Ganglia of Mice

  1971cited by this paper
• A membrane-filter technique for the detection of complementary DNA.

  1966cited by this paper
• Herpes simplex virus.

  1961cited by this paper

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  2002cites this paper
• Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice

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