Dynamic control of positional information in the early Drosophila embryo

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Nature

• Publication date

  2004-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nature02678PMID 15254541
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dynamical Analysis of Regulatory Interactions in the Gap Gene System of Drosophila melanogaster

  2004cited by this paper
• Seeing Is Believing The Bicoid Morphogen Gradient Matures

  2004cited by this paper
• Numerical recipes in C

  2002cited by this paper
• Establishment of developmental precision and proportions in the early Drosophila embryo

  2002cited by this paper
• Registration of the expression patterns of Drosophila segmentation genes by two independent methods

  2001cited by this paper
• Simultaneous Detection of RNA and Protein by In Situ Hybridization and Immunological Staining

  2001cited by this paper
• Morphogen gradient interpretation

  2001cited by this paper
• Parallel Simulated Annealing by Mixing of States

  1999cited by this paper
• Rapid preparation of a panel of polyclonal antibodies to Drosophila segmentation proteins

  1998cited by this paper
• Stripe forming architecture of the gap gene system.

  1998cited by this paper
• Model for cooperative control of positional information in Drosophila by bicoid and maternal hunchback.

  1995cited by this paper
• Mechanism of eve stripe formation.

  1995cited by this paper
• Synergy between the hunchback and bicoid morphogens is required for anterior patterning in Drosophila.

  1994cited by this paper
• Gap gene properties of the pair-rule gene runt during Drosophila segmentation.

  1994cited by this paper
• Homeobox genes and axial patterning.

  1992cited by this paper
• A connectionist model of development.

  1991cited by this paper
• The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner.

  1988cited by this paper
• The molecular genetics of embryonic pattern formation in Drosophila

  1988cited by this paper
• The molecular basis for metameric pattern in the Drosophila embryo.

  1987cited by this paper
• Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation.

  1987cited by this paper
• Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis.

  1983cited by this paper
• Mutations affecting segment number and polarity in Drosophila

  1980cited by this paper
• Space-dependent cell determination under the control of morphogen gradient.

  1978cited by this paper
• Thresholds in development.

  1977cited by this paper
• Diffusion in Embryogenesis

  1970cited by this paper
• Diffusion in embryogenesis.

  1970cited by this paper
• Positional information and the spatial pattern of cellular differentiation.

  1969cited by this paper
• Organisers and Genes

  1940cited by this paper

• Origin of the clock in Neurospora crassa

  2026cites this paper
• Gene network organization, mutation and selection collectively drive developmental pattern evolvability and predictability

  2025cites this paper
• Bulk-level maps of pioneer factor binding dynamics during the Drosophila maternal-to-zygotic transition

  2025cites this paper
• Deep learning-based high-resolution time inference for deciphering dynamic gene regulation from fixed embryos

  2025cites this paper
• Hybrid deep learning-mechanistic modeling of cellular dynamics from a spatiotemporal single-cell atlas

  2025cites this paper
• Gene network switching provides a mechanistic basis for time-to-space translation in insect embryonic patterning

  2025cites this paper
• Neighborhood-Informed Positional Information for Precise Cell Identity Specification

  2025cites this paper
• The interplay of tissue mechanics and gene regulatory networks in the evolution of morphogenesis.

  2025cites this paper
• Characterizing the regulatory logic of transcriptional control at the DNA sequence level by ensembles of thermodynamic models

  2025cites this paper
• Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization

  2025cites this paper
• Controllability of the gene regulatory network in zebrafish embryogenesis

  2025cites this paper
• LimbNET: collaborative platform for simulating spatial patterns of gene networks in limb development

  2024cites this paper
• From genes to patterns: a framework for modeling the emergence of embryonic development from transcriptional regulation

  2024cites this paper
• A phase diagram structure determines the optimal sensitivity-precision trade-off in signaling systems

  2024cites this paper
• Dynamics of morphogen source formation in a growing tissue

  2024cites this paper
• The Mechanics of Building Functional Organs

  2024cites this paper
• Automatic design of gene regulatory mechanisms for spatial pattern formation

  2024influential citation
• Temporal label recovery from noisy dynamical data

  2024cites this paper
• Two coacting shadow enhancers regulate twin of eyeless expression during early Drosophila development

  2024cites this paper
• Developmental Biology: Computational and Experimental Approaches

  2023cites this paper
• Scale invariance in early embryonic development

  2023cites this paper
• A bistable autoregulatory module in the developing embryo commits cells to binary expression fates.

  2023cites this paper
• New wave theory.

  2023cites this paper
• Shaping the scaling characteristics of gap gene expression patterns in Drosophila

  2023cites this paper
• Control of Tissue Development by Morphogens.

  2023cites this paper
• Evolution of patterning

  2023cites this paper
• Developmental Pattern Formation: Spanish Contributions from a Biophysical Perspective

  2023cites this paper
• Evo‐devo beyond development: Generalizing evo‐devo to all levels of the phenotypic evolution

  2023cites this paper
• Automatic design of gene regulatory mechanisms for spatial pattern formation

  2023cites this paper
• Deriving a genetic regulatory network from an optimization principle

  2023cites this paper
• How enhancers regulate wavelike gene expression patterns

  2022cites this paper
• Drosophila embryo as experimental model: lessons learnt from genes in axis formation

  2022cites this paper
• A timer gene network is spatially regulated by the terminal system in the Drosophila embryo

  2022cites this paper
• The macroscopic limit to synchronization of cellular clocks in single cells of Neurospora crassa

  2022cites this paper
• Philosophy of Developmental Biology

  2022cites this paper
• Cellular reaction gene regulation network for swarm robots with pattern formation maneuvering control

  2022cites this paper
• Coherent causal control: a new distinction within causation

  2022cites this paper
• A bistable autoregulatory module in the developing embryo commits cells to binary fates

  2022cites this paper
• Latent space of a small genetic network: Geometry of dynamics and information

  2022cites this paper
• Stability of Pattern Formation in Systems with Dynamic Source Regions.

  2022cites this paper
• Ensemble Methods for Identifying RNA Operons and Regulons in the Clock Network of Neurospora crassa

  2022cites this paper
• Patterning principles of morphogen gradients

  2022cites this paper
• Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis

  2022cites this paper
• Beyond genotype‐phenotype maps: Toward a phenotype‐centered perspective on evolution

  2022influential citation
• Data-driven modeling predicts gene regulatory network dynamics during the differentiation of multipotential hematopoietic progenitors

  2022cites this paper
• Solution of Mixed-Integer Optimization Problems in Bioinformatics with Differential Evolution Method

  2021cites this paper
• The early Drosophila embryo as a model system for quantitative biology.

  2021cites this paper
• Life’s Attractors Continued: Progress in Understanding Developmental Systems Through Reverse Engineering and In Silico Evolution

  2021cites this paper
• Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

  2021cites this paper
• Fitting thermodynamic-based models: Incorporating parameter sensitivity improves the performance of an evolutionary algorithm.

  2021cites this paper
• Application of Domain- and Genotype-Specific Models to Infer Post-Transcriptional Regulation of Segmentation Gene Expression in Drosophila

  2021influential citation
• Learning from Embryo Development to Engineer Self‐organizing Materials

  2021cites this paper
• Using phenotypic plasticity to understand the structure and evolution of the genotype–phenotype map

  2021cites this paper
• Finding gene network topologies for given biological function with recurrent neural network

  2021cites this paper
• Implications of diffusion and time-varying morphogen gradients for the dynamic positioning and precision of bistable gene expression boundaries

  2021cites this paper
• Data-driven modeling predicts gene regulatory network dynamics during the differentiation of multipotential progenitors

  2021cites this paper
• Dynamic Modeling of Transcriptional Gene Regulatory Networks.

  2021cites this paper
• Dynamical Modularity of the Genotype-Phenotype Map

  2021cites this paper
• Homology of process: developmental dynamics in comparative biology

  2021cites this paper
• Dynamical modules in metabolism, cell and developmental biology

  2021cites this paper
• On the evolution and development of morphological complexity: A view from gene regulatory networks

  2021cites this paper
• Multiple morphogens and rapid elongation promote segmental patterning during development

  2021cites this paper
• Inference of dynamic spatial GRN models with multi-GPU evolutionary computation

  2021cites this paper
• The many bits of positional information

  2021cites this paper
• Dynamic patterning by morphogens illuminated by cis-regulatory studies

  2021cites this paper
• Bootstrapping and Pinning down the Root Meristem; the Auxin–PLT–ARR Network Unites Robustness and Sensitivity in Meristem Growth Control

  2021cites this paper
• Unraveling the heritage of lost traits.

  2021cites this paper
• Qualitative Modeling, Analysis and Control of Synthetic Regulatory Circuits.

  2021cites this paper
• Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans

  2021cites this paper
• Dynamic regulation of anterior-posterior patterning genes in living Drosophila embryos

  2020cites this paper
• Roadmap for the multiscale coupling of biochemical and mechanical signals during development

  2020cites this paper
• Spatio-Temporal Dynamics of the Patterning of Arabidopsis Flower Meristem

  2020cites this paper
• Dynamical systems approach to evolution–development congruence: Revisiting Haeckel's recapitulation theory

  2020cites this paper
• Quantitative dissection of transcription in development yields evidence for transcription-factor-driven chromatin accessibility

  2020cites this paper
• Dynamic positioning and precision of bistable gene expression boundaries through diffusion and morphogen decay

  2020cites this paper
• Time and space in segmentation

  2020cites this paper
• Binary Expression Enhances Reliability of Messaging in Gene Networks

  2020cites this paper
• Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks

  2020cites this paper
• Modified in situ Hybridization Chain Reaction Using Short Hairpin DNAs

  2020cites this paper
• On the problem of biological form

  2020cites this paper
• Insights into mammalian morphogen dynamics from embryonic stem cell systems.

  2020cites this paper
• Dynamic positional information: Patterning mechanism versus precision in gradient-driven systems.

  2020cites this paper
• Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility

  2020cites this paper
• A matter of time: Formation and interpretation of the Bicoid morphogen gradient.

  2020cites this paper
• Gene regulatory networks in Drosophila early embryonic development as a model for the study of the temporal identity of neuroblasts

  2020cites this paper
• Formation, interpretation, and regulation of the Drosophila Dorsal/NF-κB gradient.

  2020cites this paper
• Formation of Morphogenetic Patterns in Cellular Automata

  2020cites this paper
• Embryonic geometry underlies phenotypic variation in decanalized conditions

  2020cites this paper
• Lighting up the central dogma for predictive developmental biology.

  2020cites this paper
• Cell sorting and morphogenesis in early Drosophila embryos.

  2020cites this paper
• An in silico analysis of robust but fragile gene regulation links enhancer length to robustness

  2019cites this paper
• Arthropod segmentation 1

  2019cites this paper
• Can We Compute the Embryo?

  2019cites this paper
• Relational Basis of the Organism's Self-organization A Philosophical Discussion

  2019cites this paper
• Analyzing the stability of gene expression using a simple reaction-diffusion model in an early Drosophila embryo.

  2019cites this paper
• Fully interpretable deep learning model of transcriptional control

  2019cites this paper
• Classification-Based Inference of Dynamical Models of Gene Regulatory Networks

  2019cites this paper
• Evolutionary Stability of Gene Regulatory Networks That Define the Temporal Identity of Neuroblasts

  2019cites this paper
• PDEparams: Parameter fitting toolbox for partial differential equations in Python

  2019cites this paper
• Understanding Pattern Formation in Embryos: Experiment, Theory, and Simulation

  2019cites this paper