Prostaglandin I2 is not a major metabolite of arachidonic acid in cultured endothelial cells from human foreskin microvessels.

No abstract is available for this paper.

• Publication year

  1984

• Venue

  Journal of Clinical Investigation

• Publication date

  1984-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI111509PMID 6432852PMCID PMC425247
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma.

  1984cited by this paper
• Arachidonate metabolism in vascular disorders.

  1983cited by this paper
• Prothrombin is activated on vascular endothelial cells by factor Xa and calcium.

  1983cited by this paper
• Arachidonic acid and prostaglandin endoperoxide metabolism in isolated rabbit and coronary microvessels and isolated and cultivated coronary microvessel endothelial cells.

  1983cited by this paper
• Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells.

  1982cited by this paper
• Prostacyclin and prostaglandin synthesis in isolated brain capillaries.

  1982cited by this paper
• Prostacyclin biosynthesis in vascular endothelium is not inhibited by cyclic AMP. Studies with 3-isobutyl-1-methylxanthine and forskolin.

  1982cited by this paper
• Human dermal microvascular endothelial cells in vitro: Effect of cyclic AMP on cellular morphology and proliferation rate

  1981cited by this paper
• Platelet-dependent stimulation of prostacyclin synthesis by platelet-derived growth factor

  1980cited by this paper
• A simple, rapid, and sensitive DNA assay procedure.

  1980cited by this paper
• Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cells.

  1980cited by this paper
• Isolation and growth of endothelial cells from the microvessels of the newborn human foreskin in cell culture.

  1980cited by this paper
• Inhibition of prostacyclin by treatment of endothelium with aspirin. Correlation with platelet adherence.

  1979cited by this paper
• Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls.

  1979cited by this paper
• Extraction and chromatographic procedures for purification of prostaglandins, thromboxanes, prostacyclin, and their metabolites.

  1978cited by this paper
• Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

  1977cited by this paper
• Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

  1977cited by this paper
• Cyclic AMP and the transformation of fibroblasts.

  1974cited by this paper
• Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay.

  1973cited by this paper
• Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.

  1973cited by this paper
• NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA

  1964cited by this paper

• Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease

  2024cites this paper
• A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.

  2024cites this paper
• The Pharmacological Effects of Silver Nanoparticles Functionalized with Eptifibatide on Platelets and Endothelial Cells

  2022cites this paper
• Human Skin Microcirculation.

  2020cites this paper
• Effect of Prostanoids on Human Platelet Function: An Overview

  2020cites this paper
• PGE2 and other lipids in rheumatic diseases

  2017cites this paper
• Biomaterial–Cell Tissue Interactions in Surface Engineered Carbon-Based Biomedical Implants and Devices

  2016cites this paper
• DLC thin films for implantable medical devices

  2016cites this paper
• intestinal glucose uptake from the blood regulates α 2 Blood flow-dependent prostaglandin F

  2016cites this paper
• Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease.

  2015cites this paper
• Role of Tissue Kallikrein-Related Peptidase 6 in Colon Cancer Invasion

  2015cites this paper
• Membrane lipid interactions in intestinal ischemia/reperfusion-induced Injury.

  2014cites this paper
• Targeting inflammation: multiple innovative ways to reduce prostaglandin E₂.

  2013cites this paper
• Hypoxia-induced lipid changes and their effect on innate immunity

  2013cites this paper
• Immunological function of the endothelial cell within the setting of organ transplantation.

  2011cites this paper
• Islet Endothelium: Role in Type 1 Diabetes and in Coxsackievirus Infections

  2011cites this paper
• Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation.

  2011cites this paper
• PGE2 decreases reactivity of human platelets by activating EP2 and EP4.

  2010influential citation
• From endothelial to beta cells: insights into pancreatic islet microendothelium.

  2008cites this paper
• Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox‐ independent mechanism

  2006cites this paper
• Chronic Hypoxia

  2005cites this paper
• Primary and immortalised human pancreatic islet endothelial cells: phenotypic and immunological characterisation

  2005cites this paper
• Expression of nephrin by human pancreatic islet endothelial cells

  2005cites this paper
• The Regulation and Role of Prostaglandin Biosynthesis in Cultured Bovine Glomerular Endothelial Cells”2

  2005cites this paper
• Cyclooxygenase and 5‐lipoxygenase pathways in the vessel wall: Role in atherosclerosis

  2004cites this paper
• Transcriptional regulation of cyclooxygenase-2 in the Human Microvascular Endothelial Cell Line, HMEC-1: Control by the combinatorial actions of AP2, NF-IL-6 and CRE elements

  2004cites this paper
• Leukotriene B4 enhances adherence of human polymorphonuclear leukocytes to dermal microvascular endothelial cells in vitro

  2004cites this paper
• MoleculesInduces Increased Expression of Adhesion Endothelial Cells by Coxsackie B Viruses Persistent Infection of Human Microvascular

  2003cites this paper
• Prostaglandin E , Potentiates Platelet Aggregation by Priming Protein Kinase C

  2003cites this paper
• In vivo analysis of the apoptosis-inducing effect of anti-endothelial cell antibodies in systemic sclerosis by the chorionallantoic membrane assay.

  2003cites this paper
• Persistent Infection of Human Microvascular Endothelial Cells by Coxsackie B Viruses Induces Increased Expression of Adhesion Molecules 1

  2003cites this paper
• This information is current as Molecules Induces Increased Expression of Adhesion Endothelial Cells by Coxsackie B Viruses Persistent Infection of Human Microvascular

  2003cites this paper
• Effect of ultraviolet light on the expression of adhesion molecules and T lymphocyte adhesion to human dermal microvascular endothelial cells.

  2002cites this paper
• Molecular and Cellular Hemostasis and Fibrinolysis

  2002cites this paper
• Human Intestinal Endothelium Shows High Susceptibility to Cytomegalovirus and Altered Expression of Adhesion Molecules after Infection

  2000cites this paper
• Isolation and characterization of rat gastric microvascular endothelial cells as a model for studying gastric angiogenesis in vitro.

  2000cites this paper
• Isolation of morphologically and functionally intact gastric mucosal microvessels rapid communication.

  2000cites this paper
• Endothelial injury in internal organs of University of California at Davis line 200 (UCD 200) chickens, an animal model for systemic sclerosis (Scleroderma).

  2000cites this paper
• Do prostaglandins have a salutary role in skeletal muscle ischaemia-reperfusion injury?

  1999cites this paper
• Blood flow-dependent prostaglandin F 2 a regulates intestinal glucose uptake from the blood

  1999cites this paper
• Blood flow-dependent prostaglandin F2α regulates intestinal glucose uptake from the blood.

  1999cites this paper
• Anti-beta 2-glycoprotein I antibodies bind to central nervous system.

  1998cites this paper
• Inhibition of leukocyte adherence and transendothelial migration in cultured human liver vascular endothelial cells by prostaglandin E1

  1998cites this paper
• An improved method for isolation of microvascular endothelial cells from normal and inflamed human lung

  1998cites this paper
• Anti-β2-glycoprotein I antibodies bind to central nervous system

  1998cites this paper
• A simple immunomagnetic protocol for the selective isolation and long-term culture of human dermal microvascular endothelial cells.

  1998cites this paper
• A simplified method for growth of human microvascular endothelial cells results in decreased senescence and continued responsiveness to cytokines and growth factors

  1998cites this paper
• Human umbilical vein and dermal microvascular endothelial cells show heterogeneity in response to PKC activation.

  1997cites this paper
• Gender and maturation affect glutathione status in human neonatal tissues.

  1997cites this paper
• Human umbilical vein and dermal microvascular endothelial cells show heterogeneity in response to PKC activation.

  1997cites this paper
• Isolation and culture of human gastric endothelial cells.

  1996cites this paper
• Induction of cyclo-oxygenase and nitric oxide synthase in inflammation.

  1996cites this paper
• Physiological and pathophysiological roles of eicosanoids in the microcirculation.

  1996cites this paper
• Expression of extracellular matrix genes in adult human dermal microvascular endothelial cells and their regulation by heparin and endothelial cell mitogens.

  1995cites this paper
• Group B streptococci (GBS) injure lung endothelium in vitro: GBS invasion and GBS-induced eicosanoid production is greater with microvascular than with pulmonary artery cells

  1995cites this paper
• Effect of high potassium diets on the vascular and renal prostaglandin system in stroke-prone spontaneously hypertensive rats.

  1995cites this paper
• Omega-3s and Immune/Inflammatory Responses

  1995cites this paper
• Distribution of cyclooxygenase isoforms in murine chronic granulomatous inflammation. Implications for future anti‐inflammatory therapy

  1995cites this paper
• Effects of human alpha-thrombin and 8bromo-cAMP on large and microvessel endothelial monolayer equivalent "pore" radii.

  1995cites this paper
• Isolation and longterm culture of human intestinal microvascular endothelial cells.

  1995cites this paper
• THE EFFECT OF ALA AND RADIATION ON PORPHYRIN/HEME BIOSYNTHESIS IN ENDOTHELIAL CELLS

  1995cites this paper
• Regional differences in prostaglandin production rates among porcine intrathoracic vessels.

  1994cites this paper
• Pregnancy maintenance and parturition: the role of prostaglandin in manipulating the immune and inflammatory response.

  1994cites this paper
• Increased Expression of ICAM‐1 During Reoxygenation in Brain Endothelial Cells

  1994cites this paper
• Progesterone control of interleukin-8 production in endometrium and chorio-decidual cells underlines the role of the neutrophil in menstruation and parturition.

  1994cites this paper
• Characterization of expression and modulation of cell adhesion molecules on an immortalized human dermal microvascular endothelial cell line (HMEC-1).

  1994cites this paper
• Models for Central Nervous System Complications of Antiphospholipid Syndrome

  1994cites this paper
• Induction of cyclooxygenase II in human synovial microvessel endothelial cells by interleukin-1. Inhibition by glucocorticoids.

  1994cites this paper
• Nitric oxide and human skin blood flow responses to acetylcholine and ultraviolet light

  1994cites this paper
• Biologic Effects of Parenteral Bisulfite on Human Vascular Tissue

  1993cites this paper
• Increased Immunoglobulin Binding to Cerebral Endothelium in Patients With Antiphospholipid Antibodies

  1993cites this paper
• TNF in vascular pathology: the importance of platelet-endothelium interactions.

  1993cites this paper
• Cytokine activation of human macro- and microvessel-derived endothelial cells.

  1993cites this paper
• Role of microvascular endothelial cells in inflammation.

  1993cites this paper
• Different Roles of Prostaglandins in Thromboembolic Processes in Arterioles and Venules In Vivo

  1993cites this paper
• Prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors.

  1993cites this paper
• Endothelium-dependent modulation of responses to endothelin-I in human veins.

  1993cites this paper
• Prostaglandin E2 potentiates platelet aggregation by priming protein kinase C.

  1993cites this paper
• Cellular signaling responses mediated by a novel nucleotide receptor in rabbit microvessel endothelium.

  1993cites this paper
• Regulation of vascular cell adhesion molecule 1 on human dermal microvascular endothelial cells.

  1992cites this paper
• Effect of endothelium on the actions of sympathetic and sensory nerves in the perfused rat mesentery.

  1992cites this paper
• Prostaglandin synthetase, interleukin 1 and inflammation in the skin.

  1992cites this paper
• Arachidonic Acid Metabolism, Platelets, and Thromboembolic Disease

  1992cites this paper
• Endothelial Cell Dysfunctions

  1992cites this paper
• Biochemical Pharmacology of Blood and Bloodforming Organs

  1992cites this paper
• Cytokine regulation of proliferation and ICAM-1 expression of human dermal microvascular endothelial cells in vitro.

  1992cites this paper
• Isolation, cultivation, and partial characterization of microvascular endothelium derived from human lung.

  1992cites this paper
• Endotoxin enhancement of lymphocyte adherence to cultured sheep lung microvascular endothelial cells.

  1992cites this paper
• Effects of Polyunsaturated Fatty Acids in Endothelium

  1992cites this paper
• Serial cultivation of adult human endothelium from the great saphenous vein.

  1992cites this paper
• H2 receptor-mediated responses of aortic endothelial cells to histamine.

  1992cites this paper
• HMEC-1: establishment of an immortalized human microvascular endothelial cell line.

  1992cites this paper
• Postclotting Cellular Effects of Thrombin Mediated by Interaction with High-Affinity Thrombin Receptors

  1992cites this paper
• Profile of prostanoid release following antigen challenge in vivo in the skin of man

  1991cites this paper
• Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal microvascular endothelial cells.

  1991cites this paper
• Differences in prostaglandin metabolism in cultured aortic and pulmonary arterial endothelial cells exposed to acute and chronic hypoxia.

  1991cites this paper
• Arachidonate Metabolism of Vascular Cell

  1991cites this paper
• Effects of recombinant tumor necrosis factor-alpha on cultured pulmonary artery and lung microvascular endothelial monolayers.

  1991cites this paper
• Vascular Reactivity in Atopic Eczema

  1991cites this paper
• Mechanisms of Angiogenesis in Normal and Diseased Skin

  1991cites this paper