Viral Modulation of Host Translation and Implications for Vaccine Development

A. Bakre,R. Tripp

Published 2018 in Unknown venue

ABSTRACT

Translation of mRNAs into protein is an essential mechanism of regulating gene expres- sion—and a step exploited by viruses for their own propagation. In this article, we review mechanisms that govern translation and provide an overview of the translation machin- ery, discuss some of the components involved in this process, and discuss how viruses modulate host translational controls and implications in vaccine design.

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