Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  American Journal of Physiology. Regulatory Integrative and Comparative Physiology

• Publication date

  2001-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/AJPREGU.2001.281.5.R1362PMID 11641103
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interactions of adenosine A1 and A2a receptors on renal microvascular reactivity.

  2001cited by this paper
• Adenosine signaling in outer medullary descending vasa recta.

  2001cited by this paper
• Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor

  2001influential reference
• Renal blood flow, early distal sodium, and plasma renin concentrations during osmotic diuresis.

  2000cited by this paper
• Structure and function of adenosine receptors and their genes

  2000cited by this paper
• Adenosine formed by 5'-nucleotidase mediates tubuloglomerular feedback.

  2000cited by this paper
• Effects of activation of renal adenosine A2 receptor on renal function and renin release in dogs.

  1999cited by this paper
• Efficacy in drug receptor theory: outdated concept or under-valued tool?

  1999cited by this paper
• Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney.

  1999cited by this paper
• Actions of caffeine in the brain with special reference to factors that contribute to its widespread use.

  1999cited by this paper
• Inhibition of adenosine-1 receptor-mediated preglomerular vasoconstriction in AT1Areceptor-deficient mice.

  1998cited by this paper
• Effects of intravenous adenosine on renal function in healthy human subjects.

  1996cited by this paper
• Nomenclature and classification of purinoceptors.

  1994cited by this paper
• Effects of adenosine and angiotensin on macula densa-stimulated renin secretion.

  1993cited by this paper
• Coffee consumption, blood pressure tonus and reactivity to physical challenge in 338 women.

  1993cited by this paper
• Competitive and noncompetitive reversible binding processes.

  1993cited by this paper
• Adenosine receptor gene expression in rat kidney.

  1992cited by this paper
• Vasomotor effects of purinergic agonists in isolated rabbit afferent arterioles.

  1992influential reference
• Adenosine mediates tubuloglomerular feedback response: an element of metabolic control of kidney function.

  1991cited by this paper
• Adenosine receptors and signaling in the kidney.

  1991cited by this paper
• Macula densa cell function.

  1991cited by this paper
• Tubuloglomerular feedback dependence of autoregulation in rat juxtamedullary afferent arterioles.

  1990cited by this paper
• Differential Sensitivity to Blockade by 4‐Aminopyridine of Presynaptic Receptors Regulating [3H]Acetylcholine Release from Rat Hippocampus

  1990cited by this paper
• Inhibition of tubuloglomerular feedback during adenosine1 receptor blockade.

  1990cited by this paper
• Adenosine induces mesangial cell contraction by an A1-type receptor.

  1989cited by this paper
• The selective response to adenosine of renal microvessels from hamster explants.

  1988cited by this paper
• Effect of adenosine analogues on tubuloglomerular feedback responses.

  1988cited by this paper
• Direct demonstration of macula densa-mediated renin secretion.

  1987cited by this paper
• Possible role of adenosine in the macula densa mechanism of renin release in rabbits.

  1985cited by this paper
• Role of adenosine in signal transmission of tubuloglomerular feedback.

  1982influential reference
• Adenosine induced fall in glomerular capillary pressure

  1981cited by this paper
• Adenosine as a possible mediator of metabolic control of glomerular filtration rate.

  1980cited by this paper
• Antagonistic Effects of Theophylline and Adenosine on Adrenergic Neuroeffector Transmission in the Rabbit Kidney

  1978cited by this paper
• Effects of adenosine on adrenergic neurotransmission; Prejunctional inhibition and postjunctional enhancement

  1976cited by this paper
• Ultramicroassay for plasma renin concentration in the rat using the antibody-trapping technique.

  1976cited by this paper

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• Small molecule allosteric modulation of the adenosine A1 receptor

  2023cites this paper
• Adenosine re-uptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2a receptor.

  2023cites this paper
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  2020cites this paper
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  2020cites this paper
• "Adenosine an old player with new possibilities in kidney diseases": Preclinical evidences and clinical perspectives.

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  2020cites this paper
• Knockout and Knock-in Mouse Models to Study Purinergic Signaling.

  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Adenosine as a marker and mediator of cardiovascular homeostasis: a translational perspective.

  2019cites this paper
• Bioinformatics Unmasks the Maneuverers of Pain Pathways in Acute Kidney Injury

  2019cites this paper
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  2018cites this paper
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  2018cites this paper
• Renal Adenosine in Health and Disease

  2018cites this paper
• The role of adenosine 1a receptor signaling on GFR early after the induction of sepsis.

  2018cites this paper
• Deletion of the adenosine A 1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro

  2017cites this paper
• Adenosine signaling in diabetes mellitus and associated cardiovascular and renal complications.

  2017cites this paper
• Sympathetic innervation of the kidney in health and disease: Emphasis on the role of purinergic cotransmission.

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
• Adenosine A1 receptor‐dependent and independent pathways in modulating renal vascular responses to angiotensin II

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2013cites this paper
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  2013cites this paper
• Vascular adenosine receptors; potential clinical applications.

  2013cites this paper
• Aspects of Regulation of GFR and Tubular Function in the Diabetic Kidney : Roles of Adenosine, Nitric Oxide and Oxidative Stress

  2013influential citation
• Adenosine—a physiological or pathophysiological agent?

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• The Renal Circulations and Glomerular Ultrafiltration

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• Adenosine sensitization after angiotensin II stimulation in afferent arterioles from normal rats does not occur during two‐kidney, one‐clip hypertension

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  2011cites this paper
• Regulation of renin release by local and systemic factors.

  2011cites this paper
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• Maintained tubuloglomerular feedback responses during acute inhibition of P2 purinergic receptors in mice.

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