The enzymatic degradation of phosphatidyl choline in diethyl ether.

D. Hanahan

Published 1952 in Journal of Biological Chemistry

ABSTRACT

The occurrence of enzymes which cleave unsaturated fatty acids from phospholipide has been demonstrated in a variety of sources. A recent review by Zeller (1) adequately covered the literature on this subject. Preliminary evidence has been presented for the formation of an ethersoluble complex between egg phosphatidyl choline and a phospholipase A present in commercial pancreatin, and its subsequent enzymatic degradation in diethyl ether with the release of unsaturated fatty acids and “lyso” phosphatidyl choline (2). Further details on these experiments are given.

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