Aquatic animal viruses mediated immune evasion in their host

ABSTRACT Viruses are important and lethal pathogens that hamper aquatic animals. The result of the battle between host and virus would determine the occurrence of diseases. The host will fight against virus infection with various responses such as innate immunity, adaptive immunity, apoptosis, and so on. On the other hand, the virus also develops numerous strategies such as immune evasion to antagonize host antiviral responses. Here, We review the research advances on virus mediated immune evasions to host responses containing interferon response, NF‐&kgr;B signaling, apoptosis, and adaptive response, which are executed by viral genes, proteins, and miRNAs from different aquatic animal viruses including Alloherpesviridae, Iridoviridae, Nimaviridae, Birnaviridae, Reoviridae, and Rhabdoviridae. Thus, it will facilitate the understanding of aquatic animal virus mediated immune evasion and potentially benefit the development of novel antiviral applications. HighlightsItemized are host antiviral responses in aquatic animals including fish and shrimp.Summed up are aquatic animal virus and viral components mediated evasions.Outlined are three main immune evasion strategies of aquatic animal virus.

• Publication year

  2019

• Venue

  Fish and Shellfish Immunology

• Publication date

  2019-03-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.fsi.2018.12.027PMID 30557608
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids.

  2018cited by this paper
• Diversity, evolutionary contribution and ecological roles of aquatic viruses

  2018cited by this paper
• Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids.

  2018cited by this paper
• RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides

  2018cited by this paper
• Display of GCRV vp7 protein on the surface of Escherichia coli and its immunoprotective effects in grass carp (Ctenopharyngodon idella)

  2018cited by this paper
• TBK1 from orange‐spotted grouper exerts antiviral activity against fish viruses and regulates interferon response

  2018cited by this paper
• Molecular basis of pathogenesis of emerging viruses infecting aquatic animals

  2018cited by this paper
• ICTV Virus Taxonomy Profile: Rhabdoviridae

  2018cited by this paper
• MicroRNA regulation of Toll‐like receptor signaling pathways in teleost fish

  2018cited by this paper
• A cold-blooded view of adaptive immunity

  2018cited by this paper
• Apoptotic Caspases: Multiple or Mistaken Identities?

  2018cited by this paper
• Transcriptomics Sequencing Provides Insights into Understanding the Mechanism of Grass Carp Reovirus Infection

  2018cited by this paper
• Divergent transcriptomic responses underlying the ranaviruses-amphibian interaction processes on interspecies infection of Chinese giant salamander

  2018cited by this paper
• Micropterus salmoides rhabdovirus (MSRV) infection induced apoptosis and activated interferon signaling pathway in largemouth bass skin cells

  2018cited by this paper
• Identification and characterization of a type I interferon induced by cyprinid herpesvirus 2 infection in crucian carp Carassius auratus gibelio.

  2018cited by this paper
• Under control: The innate immunity of fish from the inhibitors' perspective.

  2018cited by this paper
• Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim

  2018cited by this paper
• Identification of amino acid residues in infectious hematopoietic necrosis virus (IHNV) NV protein necessary for viral replication and pathogenicity

  2018cited by this paper
• Identification and analysis of differentially expressed microRNAs in rainbow trout (Oncorhynchus mykiss) responding to infectious hematopoietic necrosis virus infection

  2018cited by this paper
• Real-Time Dissecting the Entry and Intracellular Dynamics of Single Reovirus Particle

  2018cited by this paper
• Ferritin, cellular iron storage and regulation

  2017cited by this paper
• Xenopus-FV3 host-pathogen interactions and immune evasion.

  2017cited by this paper
• Amphibian (Xenopus laevis) tadpoles and adult frogs mount distinct interferon responses to the Frog Virus 3 ranavirus.

  2017cited by this paper
• The Ambystoma tigrinum virus (ATV) RNase III gene can modulate host PKR activation and interferon production.

  2017cited by this paper
• Two White Spot Syndrome Virus MicroRNAs Target the Dorsal Gene To Promote Virus Infection in Marsupenaeus japonicus Shrimp

  2017cited by this paper
• The expression and purification of WSSV134 from white spot syndrome virus and its inhibitory effect on caspase activity from Penaeus monodon.

  2017cited by this paper
• From fish to frogs and beyond: Impact and host range of emergent ranaviruses.

  2017cited by this paper
• Immune Response to Koi Herpesvirus (KHV) of Koi and Koi × Red Common Carp (Cyprinus carpio)

  2017cited by this paper
• NV Proteins of Fish Novirhabdovirus Recruit Cellular PPM1Bb Protein Phosphatase and Antagonize RIG-I-Mediated IFN Induction

  2017cited by this paper
• Conserved Fever Pathways across Vertebrates: A Herpesvirus Expressed Decoy TNF-α Receptor Delays Behavioral Fever in Fish

  2017cited by this paper
• Characterization of a PKR inhibitor from the pathogenic ranavirus, Ambystoma tigrinum virus, using a heterologous vaccinia virus system.

  2017cited by this paper
• Iron and Immunity.

  2017cited by this paper
• Distinct herpesvirus resistances and immune responses of three gynogenetic clones of gibel carp revealed by comprehensive transcriptomes

  2017cited by this paper
• Grass Carp Reovirus VP41 Targets Fish MITA To Abrogate the Interferon Response

  2017cited by this paper
• MHC and adaptive immunity in teleost fishes

  2017cited by this paper
• ICTV Virus Taxonomy Profile: Iridoviridae

  2017cited by this paper
• Transcriptomic analysis reveals differentially expressed genes and a unique apoptosis pathway in channel catfish ovary cells after infection with the channel catfish virus

  2017cited by this paper
• Transcriptome data analysis of grass carp (Ctenopharyngodon idella) infected by reovirus provides insights into two immune‐related genes

  2017cited by this paper
• The role of infectious hematopoietic necrosis virus (IHNV) proteins in the modulation of NF‐&kgr;B pathway during IHNV infection

  2017cited by this paper
• Pattern recognition receptors in grass carp Ctenopharyngodon idella: I. Organization and expression analysis of TLRs and RLRs

  2017cited by this paper
• Role of Viral Hemorrhagic Septicemia Virus Matrix (M) Protein in Suppressing Host Transcription

  2017cited by this paper
• Recent progress toward the identification of anti-viral immune mechanisms in decapod crustaceans.

  2017cited by this paper
• Role of Litopenaeus vannamei Yin Yang 1 in the Regulation of the White Spot Syndrome Virus Immediate Early Gene ie1

  2017cited by this paper
• Retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs) in fish: current knowledge and future perspectives

  2017cited by this paper
• Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection.

  2017cited by this paper
• TNF biology, pathogenic mechanisms and emerging therapeutic strategies

  2016cited by this paper
• Fish interferon-stimulated genes: The antiviral effectors.

  2016cited by this paper
• Complete genome sequence and architecture of crucian carp Carassius auratus herpesvirus (CaHV)

  2016cited by this paper
• Differential autophagic effects triggered by five different vertebrate iridoviruses in a common, highly permissive mandarinfish fry (MFF-1) cell model.

  2016cited by this paper
• Giant seaperch iridovirus (GSIV) induces mitochondria-mediated cell death that is suppressed by bongkrekic acid and cycloheximide in a fish cell line.

  2016cited by this paper
• Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures

  2016cited by this paper
• Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing

  2016cited by this paper
• The P Protein of Spring Viremia of Carp Virus Negatively Regulates the Fish Interferon Response by Inhibiting the Kinase Activity of TANK-Binding Kinase 1

  2016cited by this paper
• Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR

  2016cited by this paper
• The Function of Fish Cytokines

  2016cited by this paper
• Grass carp reovirus NS26 interacts with cellular lipopolysaccharide-induced tumor necrosis factor-alpha factor, LITAF

  2016cited by this paper
• Shrimp STAT was hijacked by white spot syndrome virus immediate-early protein IE1 involved in modulation of viral genes.

  2016cited by this paper
• Spring Viremia of Carp Virus N Protein Suppresses Fish IFNφ1 Production by Targeting the Mitochondrial Antiviral Signaling Protein

  2016cited by this paper
• Autophagy and apoptosis induced by Chinese giant salamander (Andrias davidianus) iridovirus (CGSIV).

  2016cited by this paper
• A tumour necrosis factor receptor-like protein encoded by Singapore grouper iridovirus modulates cell proliferation, apoptosis and viral replication.

  2016cited by this paper
• Virus-derived small RNAs in the penaeid shrimp Fenneropenaeus chinensis during acute infection of the DNA virus WSSV

  2016cited by this paper
• Viral Evasion Strategies in Type I IFN Signaling – A Summary of Recent Developments

  2016cited by this paper
• The deadly landscape of pro‐apoptotic BCL‐2 proteins in the outer mitochondrial membrane

  2016cited by this paper
• Down-regulation of MHC class I mRNA expression in the course of KHV infection.

  2016cited by this paper
• TNF-α is involved in apoptosis triggered by grass carp reovirus infection in vitro.

  2016cited by this paper
• Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp

  2015cited by this paper
• Interferons and viruses: an evolutionary arms race of molecular interactions.

  2015cited by this paper
• The Structure of the Cyprinid herpesvirus 3 ORF112-Zα·Z-DNA Complex Reveals a Mechanism of Nucleic Acids Recognition Conserved with E3L, a Poxvirus Inhibitor of Interferon Response*

  2015cited by this paper
• Whole-Genome Analysis of a Novel Fish Reovirus (MsReV) Discloses Aquareovirus Genomic Structure Relationship with Host in Saline Environments

  2015cited by this paper
• Prominent Amphibian (Xenopus laevis) Tadpole Type III Interferon Response to the Frog Virus 3 Ranavirus

  2015cited by this paper
• Hepcidin and Host Defense against Infectious Diseases

  2015cited by this paper
• Giant seaperch iridovirus infection upregulates Bas and Bak expression, leading to apoptotic death of fish cells.

  2015cited by this paper
• RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA

  2015cited by this paper
• Functional characterization of viral tumor necrosis factor receptors encoded by cyprinid herpesvirus 3 (CyHV3) genome.

  2015cited by this paper
• Cyprinid Herpesvirus 3: An Archetype of Fish Alloherpesviruses.

  2015cited by this paper
• Iridovirus CARD Protein Inhibits Apoptosis through Intrinsic and Extrinsic Pathways

  2015cited by this paper
• Virus genomes and virus-host interactions in aquaculture animals

  2015cited by this paper
• Regulation of tumour necrosis factor signalling: live or let die

  2015cited by this paper
• A white spot syndrome virus microRNA promotes the virus infection by targeting the host STAT

  2015cited by this paper
• Fish reovirus GCReV-109 VP33 protein elicits protective immunity in rare minnows

  2015cited by this paper
• Ranavirus Replication: Molecular, Cellular, and Immunological Events

  2015cited by this paper
• A Janus Kinase in the JAK/STAT signaling pathway from Litopenaeus vannamei is involved in antiviral immune response.

  2015cited by this paper
• A Piscine Birnavirus Induces Inhibition of Protein Synthesis in CHSE-214 Cells Primarily through the Induction of eIF2α Phosphorylation

  2015cited by this paper
• Cyprinid Herpesvirus 3 Il10 Inhibits Inflammatory Activities of Carp Macrophages and Promotes Proliferation of Igm+ B Cells and Memory T Cells in a Manner Similar to Carp Il10

  2015cited by this paper
• Toll-like receptor recognition of bacteria in fish: ligand specificity and signal pathways.

  2014cited by this paper
• Antiviral defense in shrimp: from innate immunity to viral infection.

  2014cited by this paper
• Innate immune responses of salmonid fish to viral infections.

  2014cited by this paper
• Determination and analysis of the complete genome sequence of Paralichthys olivaceus rhabdovirus (PORV)

  2014cited by this paper
• Two new anti-apoptotic proteins of white spot syndrome virus that bind to an effector caspase (PmCasp) of the giant tiger shrimp Penaeus (Penaeus) monodon.

  2014cited by this paper
• Susceptibility of fish and turtles to three ranaviruses isolated from different ectothermic vertebrate classes.

  2014cited by this paper
• The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling

  2014cited by this paper
• White Spot Syndrome Virus Protein Kinase 1 Defeats the Host Cell's Iron-Withholding Defense Mechanism by Interacting with Host Ferritin

  2014cited by this paper
• Complete genome sequence and comparative analysis of grass carp reovirus strain 109 (GCReV-109) with other grass carp reovirus strains reveals no significant correlation with regional distribution

  2014cited by this paper
• Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules

  2014cited by this paper
• Salmonids Have an Extraordinary Complex Type I IFN System: Characterization of the IFN Locus in Rainbow Trout Oncorhynchus mykiss Reveals Two Novel IFN Subgroups

  2014cited by this paper
• Extensive diversification of MHC in Chinese giant salamanders Andrias davidianus (Anda-MHC) reveals novel splice variants.

  2014cited by this paper
• Biology and host response to Cyprinid herpesvirus 3 infection in common carp.

  2014cited by this paper
• Thymus cDNA library survey uncovers novel features of immune molecules in Chinese giant salamander Andrias davidianus.

  2014cited by this paper
• Cellular immune responses against viral pathogens in shrimp.

  2014cited by this paper
• A short history of research on immunity to infectious diseases in fish.

  2014cited by this paper

• The epidermal ecotone: a proposed model system for marine viral ecology at the animal-environmental interface.

  2026cites this paper
• Temporal Dynamics of Immune Response Signalling in Largemouth Bass (Micropterus salmoides) Infected With Largemouth Bass Virus.

  2025cites this paper
• Studies on correlation between aquatic diseases and immunity

  2025cites this paper
• Plesiomonas shigelloides infection induced ferroptosis and apoptosis in hepatopancreas of zig-zag eel (Mastacembelus armatus).

  2025cites this paper
• Hesperetin inhibits Siniperca chuatsi rhabdovirus replication by reducing mitochondrial apoptosis in EPC cells

  2025cites this paper
• Pathogenicity characterization, immune response mechanisms, and antiviral strategies analysis underlying a LMBV strain in largemouth bass (Micropterus salmoides)

  2024cites this paper
• Cell-mediated and humoral immune responses of cyprinids induced by a live attenuated vaccine against cyprinid herpesvirus 2 infection in comparison to the virus non-permissive high temperature water treatment.

  2024cites this paper
• Liquid-liquid phase separation is essential for reovirus viroplasm formation and immune evasion

  2024cites this paper
• Singapore grouper iridovirus VP128 inhibits STING-TBK1 mediated signaling to evade antiviral immunity.

  2024cites this paper
• Identification of a novel Carassius amphitetraploid clone and its transcriptomic responses to herpesvirus infection

  2023cites this paper
• Recent insights into aquatic viruses: Emerging and reemerging pathogens, molecular features, biological effects, and novel investigative approaches

  2022cites this paper
• Identification and characterization of type I and II IFN genes in obscure puffer (Takifugu obscurus)

  2022cites this paper
• Dietary supplementation of exopolysaccharides from Lactobacillus rhamnosus GCC-3 improved the resistance of zebrafish against spring viremia of carp virus infection

  2022cites this paper
• Dietary yeast culture alleviates intestinal-hepatic damage related to TLR2-MyD88-NF-κB signaling pathway and antioxidant capability in Pseudobagrus ussuriensis.

  2022cites this paper
• Singapore Grouper Iridovirus VP131 Drives Degradation of STING-TBK1 Pathway Proteins and Negatively Regulates Antiviral Innate Immunity

  2022cites this paper
• Yeast culture improve CCl 4 ‐induced liver damage, inflammatory response via inhibition of TLR2/NF‐kB signaling pathway expression in Pseudobagrus ussuriensis

  2021cites this paper
• The C-Terminal Domain of Salmonid Alphavirus Nonstructural Protein 2 (nsP2) Is Essential and Sufficient To Block RIG-I Pathway Induction and Interferon-Mediated Antiviral Response

  2021cites this paper
• Expression of ssa-miR-155 during ISAV infection in vitro: putative role as a modulator of the immune response in Salmo salar.

  2021cites this paper
• Identification and functional characterization of three irf7 transcript variants in obscure puffer (Takifugu obscurus).

  2021cites this paper
• Cloning of rpl10 in spotted knifejaw ( Oplegnathus punctatus ) and expression pattern analysis after iridovirus infection

  2020cites this paper
• Temperature affects the host hematological and cytokine response following experimental ranavirus infection in red-eared sliders (Trachemys scripta elegans)

  2020cites this paper
• Transcriptome analysis provides insights into the antiviral response in the spleen of gibel carp (Carassius auratus gibelio) after poly I: C treatment.

  2020cites this paper
• Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol

  2020cites this paper
• Yeast cultures alleviate gossypol induced inflammatory response in liver tissue of Ussuri catfish (Pseudobagrus ussuriensis)

  2020cites this paper
• Identification, expression profiles and antiviral activities of a type I IFN from gibel carp Carassius auratus gibelio.

  2019cites this paper
• Identification of fish CMPK2 as an interferon stimulated gene against SVCV infection.

  2019cites this paper
• Interaction between Two Iridovirus Core Proteins and Their Effects on Ranavirus (RGV) Replication in Cells from Different Species

  2019cites this paper
• PPAR-δ of orange-spotted grouper exerts antiviral activity against fish virus and regulates interferon signaling and inflammatory factors.

  2019cites this paper