Whole-brain and regional brain atrophy in amyotrophic lateral sclerosis.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  AJNR. American journal of neuroradiology

• Publication date

  2007-02-01

• Fields of study

  Medicine

• Identifiers
  PMID 17296989PMCID PMC7977419
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Voxel-based morphometry

  2007cited by this paper
• Frontotemporal white matter changes in amyotrophic lateral sclerosis

  2005cited by this paper
• The size distribution of neurons in the motor cortex in amyotrophic lateral sclerosis

  2005cited by this paper
• A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD

  2005cited by this paper
• Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia.

  2005cited by this paper
• Prevalence and patterns of cognitive impairment in sporadic ALS

  2005cited by this paper
• Cognitive function in bulbar– and spinal–onset amyotrophic lateral sclerosis

  2005cited by this paper
• Amyotrophic lateral sclerosis with dementia: The clinicopathological spectrum

  2004cited by this paper
• A voxel based morphometry study on mild cognitive impairment

  2004cited by this paper
• Why voxel-based morphometric analysis should be used with great caution when characterizing group differences

  2004cited by this paper
• Reduced NAA in motor and non‐motor brain regions in amyotrophic lateral sclerosis: a cross‐sectional and longitudinal study

  2004cited by this paper
• T2-low signal intensity in the cortex in multiple system atrophy

  2004cited by this paper
• Are amyotrophic lateral sclerosis patients cognitively normal?

  2003influential reference
• T2-low signal intensity in the cortex in multiple system atrophy.

  2003cited by this paper
• Cognitive impairment, frontotemporal dementia, and the motor neuron diseases

  2003cited by this paper
• Memory deficits and retrieval processes in ALS 1

  2003influential reference
• Left/right asymmetry of atrophy in semantic dementia

  2003cited by this paper
• Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection

  2003cited by this paper
• Neuropathology with Clinical Correlations of Sporadic Amyotrophic Lateral Sclerosis: 102 Autopsy Cases Examined Between 1962 and 2000

  2003cited by this paper
• The diagnostic utility of FLAIR imaging in clinically verified amyotrophic lateral sclerosis

  2003cited by this paper
• A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis

  2003cited by this paper
• Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder.

  2003cited by this paper
• Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis

  2002cited by this paper
• Hemispheric asymmetry and aging: right hemisphere decline or asymmetry reduction.

  2002cited by this paper
• MR correlates of cerebral atrophy in patients with multiple sclerosis

  2002cited by this paper
• Frontal lobe dysfunction in amyotrophic lateral sclerosis.

  2002cited by this paper
• Decrease in N-acetylaspartate/creatine ratio in the motor area and the frontal lobe in amyotrophic lateral sclerosis

  2001cited by this paper
• Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS

  2001cited by this paper
• "Voxel-Based Morphometry" Should Not Be Used with Imperfectly Registered Images

  2001cited by this paper
• Studies of Interference in Serial Verbal Reactions

  2001cited by this paper
• Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm

  2001cited by this paper
• Cognitive impairment in sporadic ALS: A pathologic continuum underlying a multisystem disorder

  2001cited by this paper
• A voxel-based morphometric study of ageing in 465 normal adult human brains

  2001cited by this paper
• Progress in Clinical Neurosciences: The Evidence for ALS as a Multisystems Disorder of Limited Phenotypic Expression

  2001cited by this paper
• Cognitive impairment in sporadic ALS

  2001cited by this paper
• MR imaging and localized proton spectroscopy of the precentral gyrus in amyotrophic lateral sclerosis.

  2000cited by this paper
• Unchanged total number of neurons in motor cortex and neocortex in amyotrophic lateral sclerosis: a stereological study.

  2000cited by this paper
• Voxel-based morphometry--the methods.

  2000cited by this paper
• Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS

  1999cited by this paper
• Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research.

  1999cited by this paper
• A prospective study of cognitive impairment in ALS

  1999cited by this paper
• Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria.

  1999cited by this paper
• Frontotemporal lobar degeneration

  1998cited by this paper
• Functional heterogeneity of left inferior frontal cortex as revealed by fMRI

  1997cited by this paper
• Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study.

  1996cited by this paper
• The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The Group for the Standardization of the Mental Deterioration Battery.

  1996cited by this paper
• The Mini-Mental State Examination in general medical practice: clinical utility and acceptance.

  1996cited by this paper
• The Mental Deterioration Battery: Normative Data, Diagnostic Reliability and Qualitative Analyses of Cognitive Impairment

  1996cited by this paper
• The Amyotrophic Lateral Sclerosis Functional Rating Scale. Assessment of activities of daily living in patients with amyotrophic lateral sclerosis. The ALS CNTF treatment study (ACTS) phase I-II Study Group.

  1996cited by this paper
• Prevalence and correlates of neuropsychological deficits in amyotrophic lateral sclerosis.

  1996cited by this paper
• Statistical parametric maps in functional imaging: A general linear approach

  1994cited by this paper
• Frontal lobe atrophy in motor neuron diseases.

  1994cited by this paper
• The mini‐mental state examination: Normative study of an Italian random sample

  1993cited by this paper
• Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis.

  1991cited by this paper
• [Italian standardization and classification of Neuropsychological tests. The Italian Group on the Neuropsychological Study of Aging].

  1987cited by this paper
• “Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician

  1975cited by this paper
• An inventory for measuring depression.

  1961cited by this paper
• Short-term retention of individual verbal items.

  1959cited by this paper

• Multimodal Neuroimaging‐Guided Stratification in Amyotrophic Lateral Sclerosis Reveals Three Disease Subtypes: A Multi‐Cohort Analysis

  2025cites this paper
• Emerging roles of the ciliary-mitochondrial axis in cellular homeostasis and neuroprotection

  2025cites this paper
• Neurite orientation dispersion and density imaging quantifies microstructural impairment in the thalamus and its connectivity in amyotrophic lateral sclerosis

  2024cites this paper
• MRI Voxel-Based Morphometry to Classify Brain Structural Alterations in Parkinson's Disease

  2024cites this paper
• Integration of graph network with kernel SVM and logistic regression for identification of biomarkers in SCA12 and its diagnosis.

  2024cites this paper
• Graph theory network analysis reveals widespread white matter damage in brains of patients with classic ALS

  2024cites this paper
• Amyotrophic lateral sclerosis in a tricenarian female

  2024cites this paper
• BayesKAT: bayesian optimal kernel-based test for genetic association studies reveals joint genetic effects in complex diseases

  2024cites this paper
• BayesKAT: Bayesian Optimal Kernel-based Test for genetic association studies reveals joint genetic effects in complex diseases

  2023cites this paper
• M1/precuneus ratio as a surrogate marker of upper motor neuron sign in ALS.

  2023cites this paper
• Aberrant Multimodal Connectivity Pattern Involved in Default Mode Network and Limbic Network in Amyotrophic Lateral Sclerosis

  2023cites this paper
• Differential cortical gray matter changes in early- and late-onset patients with amyotrophic lateral sclerosis.

  2023cites this paper
• Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity

  2022cites this paper
• of of neurodegeneration in patients with ALS and

  2022cites this paper
• Graph theory network analysis provides brain MRI evidence of a partial continuum of neurodegeneration in patients with UMN-predominant ALS and ALS-FTD

  2022cites this paper
• Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases—A systematic review and meta-analysis

  2022cites this paper
• Tackling clinical heterogeneity across the amyotrophic lateral sclerosis–frontotemporal dementia spectrum using a transdiagnostic approach

  2021influential citation
• IGF-1/GLP-1 Signaling Activator 4-hydroxyisoleucine (4-HI) Prevent Neurobehavioral and Neurochemical Defects in Methylmercury-induced Experimental Model of ALS: Insights From CSF, Blood Plasma and Brain Homogenate Samples in Rats

  2021cites this paper
• The extended scope of neuroimaging and prospects in brain atrophy mitigation: A systematic review

  2021cites this paper
• Network diffusion model predicts neurodegeneration in limb-onset Amyotrophic Lateral Sclerosis

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Modeling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis

  2021cites this paper
• Neurophysiological aspects of the completely locked-in syndrome in patients with advanced amyotrophic lateral sclerosis.

  2021cites this paper
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  2020cites this paper
• The impact of cognitive and behavioral impairment in amyotrophic lateral sclerosis

  2020cites this paper
• Phenotypic variability in ALS-FTD and effect on survival

  2020cites this paper
• Degeneration of gray and white matter differs between hypometabolic and hypermetabolic brain regions in a patient with ALS-FTD: a longitudinal MRI − PET multimodal study

  2020cites this paper
• Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement

  2020cites this paper
• Tissue Engineering and Biomaterial Strategies to Elicit Endogenous Neuronal Replacement in the Brain

  2020cites this paper
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  2019influential citation
• Progress of magnetic resonance imaging in amyotrophic lateral sclerosis

  2019cites this paper
• Biomarkers in Motor Neuron Disease: A State of the Art Review

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Changes in Retinal OCT and Their Correlations with Neurological Disability in Early ALS Patients, a Follow-Up Study

  2019cites this paper
• Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis

  2019cites this paper
• Speech network regional involvement in bulbar ALS: a multimodal structural MRI study

  2019cites this paper
• White matter volume loss in amyotrophic lateral sclerosis: A meta‐analysis of voxel‐based morphometry studies

  2018cites this paper
• Gray Matter Volume Changes over the Whole Brain in the Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Voxel-based Morphometry Study.

  2018cites this paper
• Texture Analysis to Detect Cerebral Degeneration in Amyotrophic Lateral Sclerosis

  2018cites this paper
• Cord cross-sectional area at foramen magnum as a correlate of disability in amyotrophic lateral sclerosis

  2018cites this paper
• Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

  2018cites this paper
• Reduced retinal nerve fiber layer (RNFL) thickness in ALS patients: a window to disease progression

  2018cites this paper
• Kana and Kanji Agraphia in Patients with Amyotrophic Lateral Sclerosis: Characteristics and Responsible Brain Regions.

  2018cites this paper
• Gray matter and white matter changes in non-demented amyotrophic lateral sclerosis patients with or without cognitive impairment: A combined voxel-based morphometry and tract-based spatial statistics whole-brain analysis

  2018cites this paper
• Amyotrophic Lateral Sclerosis and its Mimics/Variants: A Comprehensive Review

  2018cites this paper
• Region‐specific atrophy of precentral gyrus in patients with amyotrophic lateral sclerosis

  2018cites this paper
• Clinical and Radiological Markers of Extra-Motor Deficits in Amyotrophic Lateral Sclerosis

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses

  2018cites this paper
• Frontal assessment battery and frontal atrophy in amyotrophic lateral sclerosis

  2017influential citation
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• Brain Parenchymal Fraction in Healthy Adults—A Systematic Review of the Literature

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Optical Coherence Tomography in Neurodegenerative Disorders

  2016cites this paper
• Assessment of the upper motor neuron in amyotrophic lateral sclerosis.

  2016cites this paper
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  2016cites this paper
• Cerebral Degeneration in Amyotrophic Lateral Sclerosis Revealed by 3-Dimensional Texture Analysis

  2016influential citation
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  2016cites this paper
• Voxel-Wise Meta-Analysis of Gray Matter Changes in Amyotrophic Lateral Sclerosis

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Computer-based magnetic resonance imaging as a tool in clinical diagnosis in neurodegenerative diseases

  2016cites this paper
• Steroid Profiling in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis.

  2016cites this paper
• Brain Parenchymal Fraction: A Relatively Simple MRI Measure to Clinically Distinguish ALS Phenotypes

  2015cites this paper
• Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis

  2015cites this paper
• Morphometric correlates of dysarthric deficit in amyotrophic lateral sclerosis

  2015cites this paper
• An Assessment of Possible Neuropathology and Clinical Relationships in 46 Sporadic Amyotrophic Lateral Sclerosis Patient Autopsies

  2015cites this paper
• Morphometric and neurochemical alterations found in l-BMAA treated rats.

  2015cites this paper
• Microstructural Changes across Different Clinical Milestones of Disease in Amyotrophic Lateral Sclerosis

  2015cites this paper
• Depression and disease progression in amyotrophic lateral sclerosis: A comprehensive meta-regression analysis

  2015cites this paper
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  2015cites this paper
• Motor and extra-motor gray matter atrophy in amyotrophic lateral sclerosis: quantitative meta-analyses of voxel-based morphometry studies.

  2015cites this paper
• Diffusion-MRI in neurodegenerative disorders.

  2015cites this paper
• Neuroimaging distinction between neurological and psychiatric disorders†

  2015cites this paper
• Cognition and behavior in motor neuron disease

  2015cites this paper
• What Does Imaging Reveal About the Pathology of Amyotrophic Lateral Sclerosis?

  2015cites this paper
• [Overlapping features of frontotemporal dementia and amyotrophic lateral sclerosis].

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014influential citation
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper