Protein-protein Interactions

• What is proteomics? • Why protein-protein interactions are important • Examples of protein-protein interactions • Common protein-protein interaction methods in the lab • High throughput methods • 2D gels and mass spectrometry We will try to cover…… PROTEOME A set of PROTeins encoded bya genOME (The cell can be thought of as a metropolitan city……… • Each person (GENE) contributes to making the city (CELL) thrive and function • We then identify the names of all the people (SEQUENCING) and their occupation (PROTEIN FUNCTION) • We then find out where they work (CELLULAR LOCALIZATION) and who they interact with in their workplace (other proteins, nucleic acids, phospholipids, carbohydrates)

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  DOI 10.1007/978-1-4020-8268-9_8
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