Intranasal Bioavailability of Insulin from Carbopol-Based Gel Spray in Rabbits

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Drug Delivery

• Publication date

  2004-01-01

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1080/10717540490494050PMID 15742554
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1988cited by this paper
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  1988cited by this paper
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  1987influential reference
• The effect of molecular size on the nasal absorption of water‐soluble compounds in the albino rat

  1987cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1985influential reference
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  1981cited by this paper

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