Síndrome de ovario poliquístico y complicaciones metabólicas: más allá del exceso de andrógenos

RESUMEN El sindrome del ovario poliquistico (SOP) es la alteracion endocrinologica mas comun que afecta a las mujeres en edad reproductiva con estudios que reportan una prevalencia de hasta un 21%. Existen dife-rentes criterios de diagnostico que describen diferentes fenotipos en las pacientes. El SOP trae grandes implicaciones en la salud femenina ya que se ha relacionado con alteraciones endocrinologicas, metaboli-cas y de fertilidad. Actualmente hay mayor conocimiento sobre la patogenesis de la enfermedad y se han relacionado nuevos marcadores bioquimicos tanto en mecanismos fisiopatologicos propios del SOP, como de enfermedades asociadas, permitiendo mejor identificacion y manejo de esta poblacion, lo que implica un avance para el desarrollo de posibles terapias y metodos diagnosticos mas eficaces.PALABRAS CLAVE: Sindrome del ovario poliquistico, sindrome metabolico, resistencia a la Insulina, hiperandrogenismo SUMMARY Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder, it affects mostly women of reproductive age and some studies have reported that up to 21% of women present this syndrome. There are different diagnostic criteria for PCOS that characterize these patients into one of various phenotypes. This disorder has great implications on women’s health because it has been linked to other metabolic, endocrine and fertility disorders. Due to recent investigations, there has been a surge of new information about the pathogenesis of this disease, which in turn has helped explore new biochemical markers and pa-thophysiological mechanisms of PCOS and associated diseases, thus allowing a clearer identification and better management of these patients. This new information can lead to a breakthrough in the development of potential therapies and more effective diagnostic methods.KEY WORDS:

• Publication year

  2015

• Venue

  Revista chilena de obstetricia y ginecología

• Publication date

  2015-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.4067/S0717-75262015000600013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Total body fat and central fat mass independently predict insulin resistance but not hyperandrogenemia in women with polycystic ovary syndrome.

  2015cited by this paper
• Oxidative stress and cardiovascular complications in polycystic ovarian syndrome.

  2015cited by this paper
• The association between hyperandrogenemia and the metabolic syndrome in morbidly obese women

  2015cited by this paper
• Association of Insulin Resistance with Lipid Profile, Metabolic Syndrome, and Hormonal Aberrations in Overweight or Obese Women with Polycystic Ovary Syndrome

  2015cited by this paper
• Testosterone to dihydrotestosterone ratio as a new biomarker for an adverse metabolic phenotype in the polycystic ovary syndrome.

  2015cited by this paper
• Polycystic ovaries and obesity.

  2015cited by this paper
• A case–control observational study of insulin resistance and metabolic syndrome among the four phenotypes of polycystic ovary syndrome based on Rotterdam criteria

  2015cited by this paper
• Increased thrombin generation in women with polycystic ovary syndrome: A pilot study on the effect of metformin and oral contraceptives.

  2015cited by this paper
• Hyperandrogenemia in Polycystic Ovary Syndrome: Exploration of the Role of Free Testosterone and Androstenedione in Metabolic Phenotype

  2014cited by this paper
• What do we know about metabolic syndrome in adolescents with PCOS?

  2014cited by this paper
• University of Birmingham Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome : the utility of serum androstenedione

  2014cited by this paper
• Visceral Adiposity Index: An Indicator of Adipose Tissue Dysfunction

  2014cited by this paper
• Complementary Therapy in Polycystic Ovary Syndrome

  2014cited by this paper
• Polycystic ovary syndrome: implications of metabolic dysfunction.

  2014cited by this paper
• Nonalcoholic fatty liver disease and polycystic ovary syndrome.

  2014cited by this paper
• Risk of Psychiatric Disorders following Polycystic Ovary Syndrome: A Nationwide Population-Based Cohort Study

  2014cited by this paper
• Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

  2014cited by this paper
• Physical activity and mental health in women with Polycystic Ovary Syndrome

  2014cited by this paper
• Obesity, insulin resistance and comorbidities? Mechanisms of association.

  2014cited by this paper
• Afamin serum concentrations are associated with insulin resistance and metabolic syndrome in polycystic ovary syndrome

  2014cited by this paper
• Influence of a positive family history of both type 2 diabetes and PCOS on metabolic and endocrine parameters in a large cohort of PCOS women.

  2014cited by this paper
• Metabolic profile of the different phenotypes of polycystic ovary syndrome in two Latin American populations.

  2014cited by this paper
• Metabolic syndrome and non-alcoholic fatty liver disease in liver surgery: The new scourges?

  2014cited by this paper
• Polycystic ovary syndrome: reviewing diagnosis and management of metabolic disturbances.

  2014cited by this paper
• Polycystic ovary syndrome: current status and future perspective.

  2014cited by this paper
• Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

  2013cited by this paper
• Proteomic biomarkers of type 2 diabetes mellitus risk in women with polycystic ovary syndrome.

  2013cited by this paper
• Comparison of markers of insulin resistance and circulating androgens between women with polycystic ovary syndrome and women with metabolic syndrome.

  2013cited by this paper
• Polycystic Ovary Syndrome Is a Risk Factor for Type 2 Diabetes

  2012cited by this paper
• Inflammation in Polycystic Ovary Syndrome: underpinning of insulin resistance and ovarian dysfunction.

  2012cited by this paper
• PCOS, coronary heart disease, stroke and the influence of obesity: a systematic review and meta-analysis.

  2011cited by this paper
• Polycystic ovary syndrome and impact on health

  2011cited by this paper
• Polycystic Ovary Syndrome and Risk for Long-Term Diabetes and Dyslipidemia

  2011cited by this paper
• Comparison of diabetes mellitus and insulin resistance screening methods for women with polycystic ovary syndrome.

  2011cited by this paper
• The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria.

  2010cited by this paper
• The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.

  2009cited by this paper
• Metabolic syndrome—a new world‐wide definition. A Consensus Statement from the International Diabetes Federation

  2006cited by this paper
• The metabolic syndrome--a new worldwide definition.

  2005cited by this paper
• Insulin resistance, polycystic ovary syndrome, and type 2 diabetes mellitus.

  2002cited by this paper
• Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in Asian women with polycystic ovary syndrome

  2001cited by this paper

• Prevalencia del síndrome de ovario poliquístico en mujeres en edad reproductiva en Nicaragua, 2023

  2025cites this paper
• Síndrome de ovario poliquístico, más allá de una afección en la reproducción.

  2023cites this paper
• Prevalência da síndrome dos ovários policísticos em uma instituição de ensino superior da cidade de Cajazeiras – PB

  2021cites this paper
• Resistencia a la insulina en mujeres con síndrome de ovario poliquístico

  2020cites this paper
• Infertilidad por síndrome de ovario poliquístico en mujeres del municipio Las Tunas

  2019cites this paper
• Intervenciones dietéticas en el tratamiento del síndrome del ovario poliquístico. Una revisión bibliográfica

  year unknowncites this paper