Inflammatory cardiac valvulitis in TAX1BP1‐deficient mice through selective NF‐κB activation

No abstract is available for this paper.

• Publication year

  2008

• Venue

  EMBO Journal

• Publication date

  2008-02-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/emboj.2008.5PMID 18239685PMCID PMC2262037
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1.

  2007cited by this paper
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  2007cited by this paper
• Ubiquitin: tool and target for intracellular NF-kappaB inhibitors.

  2006cited by this paper
• Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].

  2006cited by this paper
• ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB.

  2006cited by this paper
• Nuclear factor-kappaB in cancer development and progression.

  2006cited by this paper
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  2006cited by this paper
• ABIN-1 Binds to NEMO/IKKγ and Co-operates with A20 in Inhibiting NF-κB*

  2006cited by this paper
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  2005cited by this paper
• A20 inhibits NF-κB activation by dual ubiquitin-editing functions

  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
• A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions.

  2005cited by this paper
• Ubiquitin signalling in the NF-kappaB pathway.

  2005cited by this paper
• Ubiquitylation and cell signaling

  2005cited by this paper
• Ubiquitin signalling in the NF-κB pathway

  2005cited by this paper
• Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)

  2005cited by this paper
• De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

  2004cited by this paper
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  2004cited by this paper
• The Kinase Activity of Rip1 Is Not Required for Tumor Necrosis Factor-α-induced IκB Kinase or p38 MAP Kinase Activation or for the Ubiquitination of Rip1 by Traf2*

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  2004cited by this paper
• NF-κB Is Essential for Induction of CYLD, the Negative Regulator of NF-κB

  2004cited by this paper
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  2004influential reference
• Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.

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  2003influential reference
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  2002influential reference
• NF-kappaB at the crossroads of life and death.

  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
• The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense

  2000cited by this paper
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  2000cited by this paper
• Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

  2000cited by this paper
• T6BP, a TRAF6-interacting protein involved in IL-1 signaling.

  2000influential reference
• The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

  1999cited by this paper
• The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

  1999cited by this paper
• The cytokine‐inducible zinc finger protein A20 inhibits IL‐1‐induced NF‐κB activation at the level of TRAF6

  1999cited by this paper
• Regulation of NF-kappa B activation by MAP kinase cascades.

  1997cited by this paper
• Regulation of NF-κB Activation by MAP Kinase Cascades

  1997cited by this paper
• IRAK: A Kinase Associated with the Interleukin-1 Receptor

  1996cited by this paper
• Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.

  1995cited by this paper
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

  1994cited by this paper
• Diagnosis of rheumatic fever. A guide to the criteria and manifestations.

  1986cited by this paper
• Rheumatic fever.

  1954cited by this paper

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  2014cites this paper
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