Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation

Lucía Gregorio-Teruel,P. Valente,J. González-Ros,G. Fernández-Ballester,A. Ferrer-Montiel

Published 2014 in The Journal of General Physiology

ABSTRACT

Residues I696 and W697 are crucial to coupling between the TRPV1 ligand- and voltage-sensing domains and the channel pore.

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