Identification of a Tetramerization Domain in the C Terminus of the Vanilloid Receptor

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neuroscience

• Publication date

  2004-06-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1523/JNEUROSCI.0202-04.2004PMID 15190102PMCID PMC6729306
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SWISS-MODEL: an automated protein homology-modeling server

  2003cited by this paper
• Functional Role of C-Terminal Cytoplasmic Tail of Rat Vanilloid Receptor 1

  2003influential reference
• C‐terminal domains implicated in the functional surface expression of potassium channels

  2003influential reference
• Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)

  2003cited by this paper
• A comparison of the genes coding for canonical TRP channels and their M, V and P relatives.

  2003influential reference
• Structural basis for modulation and agonist specificity of HCN pacemaker channels

  2003cited by this paper
• A Modular PIP2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity

  2003cited by this paper
• Structural determinant of TRPV1 desensitization interacts with calmodulin

  2003cited by this paper
• TRP channels as cellular sensors

  2003influential reference
• Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations.

  2002influential reference
• cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation.

  2002cited by this paper
• Direct Phosphorylation of Capsaicin Receptor VR1 by Protein Kinase Cε and Identification of Two Target Serine Residues*

  2002influential reference
• TRP channel proteins and signal transduction.

  2002cited by this paper
• Molecular Determinants of the Sensory and Motor Neuron-derived Factor Insertion into Plasma Membrane*

  2002cited by this paper
• p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia.

  2002cited by this paper
• Attenuation of thermal nociception and hyperalgesia by VR1 blockers

  2002cited by this paper
• Functional Analysis of Capsaicin Receptor (Vanilloid Receptor Subtype 1) Multimerization and Agonist Responsiveness Using a Dominant Negative Mutation

  2001cited by this paper
• Molecular mechanism of cAMP modulation of HCN pacemaker channels

  2001influential reference
• Molecular Architecture of Full-Length KcsA

  2001cited by this paper
• Analysis of the Native Quaternary Structure of Vanilloid Receptor 1* 210

  2001cited by this paper
• The vanilloid receptor: a molecular gateway to the pain pathway.

  2001cited by this paper
• The trp ion channel family

  2001influential reference
• Identification of a novel tetramerization domain in large conductance K(ca) channels.

  2001cited by this paper
• Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue.

  2001influential reference
• Predicting adaptive evolution

  2001cited by this paper
• Renaturation of Recombinant Human Neurotrophin-3 from Inclusion Bodies

  2000cited by this paper
• Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties*

  2000cited by this paper
• Induction of vanilloid receptor channel activity by protein kinase C

  2000influential reference
• Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

  2000cited by this paper
• Impaired nociception and pain sensation in mice lacking the capsaicin receptor.

  2000cited by this paper
• From worm to man: three subfamilies of TRP channels.

  2000cited by this paper
• An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1.

  2000cited by this paper
• C-Linker of Cyclic Nucleotide–gated Channels Controls Coupling of Ligand Binding to Channel Gating

  1999cited by this paper
• Renaturation of recombinant human neurotrophin‐3 from inclusion bodies using a suppressor agent of aggregation

  1998cited by this paper
• The yeast two-hybrid system

  1997cited by this paper
• SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

  1997influential reference
• The capsaicin receptor: a heat-activated ion channel in the pain pathway

  1997cited by this paper
• Coiled coils: new structures and new functions.

  1996cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• Predicting coiled coils from protein sequences

  1991cited by this paper
• WHAT IF: a molecular modeling and drug design program.

  1990cited by this paper

• TRPV1 from the TRP family: Structure, function, implication in autoimmune diseases and potential therapies

  2026cites this paper
• Mechanosensing of Shear Stress and Uterine Spiral Artery Remodeling by Invasive Trophoblasts in Early Pregnancy

  2025cites this paper
• New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine

  2025cites this paper
• Neurotoxins Acting on TRPV1—Building a Molecular Template for the Study of Pain and Thermal Dysfunctions

  2025cites this paper
• The Molecular Biology of Placental Transport of Calcium to the Human Foetus

  2025cites this paper
• Mechanosensitive TRPV4 channel guides maturation and organization of the bilayered mammary epithelium

  2024cites this paper
• Progress in the Structural Basis of thermoTRP Channel Polymodal Gating

  2023cites this paper
• TRPV1: A promising therapeutic target for skin aging and inflammatory skin diseases

  2023cites this paper
• Carcinogenesis and Metastasis: Focus on TRPV1-Positive Neurons and Immune Cells

  2023cites this paper
• Mechanosensitive Ion Channels and Their Role in Cancer Cells

  2023cites this paper
• ROLE OF MECHANOSENSITIVE CHANNELS/RECEPTORS IN ATHEROSCLEROSIS.

  2022cites this paper
• Transient Receptor Potential Vanilloid1 (TRPV1) Channel Opens Sesame of T Cell Responses and T Cell-Mediated Inflammatory Diseases

  2022influential citation
• Vasopressin regulation of maternal body fluid balance in pregnancy and lactation: A role for TRPV channels?

  2022cites this paper
• TRPV Protein Family—From Mechanosensing to Cancer Invasion

  2021cites this paper
• Properties and Differential Expression of H+ Receptors in Dorsal Root Ganglia: Is a Labeled-Line Coding for Acid Nociception Possible?

  2021cites this paper
• Probing temperature and capsaicin-induced activation of TRPV1 channel via computationally guided point mutations in its pore and TRP domains.

  2020cites this paper
• Eugenol induces potent vasorelaxation in uterine arteries from pregnant goats – A promising natural therapeutic agent for hypertensive disorders of pregnancy

  2020cites this paper
• Endothelial Ca2+ signaling-dependent vasodilation through transient receptor potential channels

  2020cites this paper
• Supraspinal in Pain and Psychiatric Disorders

  2020cites this paper
• Emerging role of transient receptor potential (TRP) channels in cancer progression

  2020cites this paper
• Calcium signals that determine vascular resistance

  2019cites this paper
• Capsaicin: Physicochemical properties, cutaneous reactions and potential applications in painful and inflammatory conditions

  2019cites this paper
• Supraspinal in Pain and Psychiatric Disorders

  2019cites this paper
• In Silico Approaches for TRP Channel Modulation.

  2019cites this paper
• Fluorescence-Based Functional Assays for Ca2+-Permeable ThermoTRP Channels.

  2019cites this paper
• TRPM6 N-Terminal CaM- and S100A1-Binding Domains

  2019cites this paper
• Supraspinal in Pain and Psychiatric Disorders

  2019cites this paper
• Supraspinal TRPV1 in Pain and Psychiatric Disorders

  2019cites this paper
• Detection and modulation of capsaicin perception in the human oral cavity.

  2018cites this paper
• Molecular basis for the sensitivity of TRP channels to polyunsaturated fatty acids

  2018cites this paper
• TRP Channels in Angiogenesis and Other Endothelial Functions

  2018cites this paper
• Involvement of MrgprC in Electroacupuncture Analgesia for Attenuating CFA-Induced Thermal Hyperalgesia by Suppressing the TRPV1 Pathway

  2018cites this paper
• TRP channels in calcium homeostasis: from hormonal control to structure-function relationship of TRPV5 and TRPV6.

  2017cites this paper
• Lipids as central modulators of sensory TRP channels.

  2017cites this paper
• Versatile Roles of Intracellularly Located TRPV1 Channel

  2017influential citation
• Taste and Smell

  2017influential citation
• A Gate Hinge Controls the Epithelial Calcium Channel TRPV5

  2017cites this paper
• Mechanisms of ANO1 channel activation in sensory neurons

  2017cites this paper
• TRPC Channel Structure and Properties.

  2017cites this paper
• Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons

  2017cites this paper
• Primary sensory neuron-specific interference of TRPV1 signaling by adeno-associated virus-encoded TRPV1 peptide aptamer attenuates neuropathic pain

  2017cites this paper
• The skin as a window on mechanisms of neuropathy and neuropathic pain

  2017cites this paper
• Effects of Herpes Simplex Virus Vectors Encoding Poreless TRPV1 or Protein Phosphatase 1α in a Rat Cystitis Model induced by Hydrogen Peroxide

  2017cites this paper
• Differential mechanism of TRPV1 sensitization in peptidergic and nonpeptidergic nociceptors

  2016cites this paper
• Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening

  2016cites this paper
• Acidic tumor microenvironment in human melanoma

  2016cites this paper
• Calcium Entry Through Thermosensory Channels.

  2016cites this paper
• Chemical Activation of Sensory TRP Channels

  2016cites this paper
• TRPV4: Molecular Conductor of a Diverse Orchestra.

  2016cites this paper
• Characterization and evaluation of trpv1 and trpm8 antagonists as potential therapeutic tools for treating pain

  2016cites this paper
• Integrating TRPV1 Receptor Function with Capsaicin Psychophysics

  2016cites this paper
• Polymodal Transient Receptor Potential Vanilloid Type 1 Nocisensor: Structure, Modulators, and Therapeutic Applications.

  2016cites this paper
• Whirlin increases TRPV1 channel expression and cellular stability.

  2016cites this paper
• Function and Regulation of Polycystin-2 and Epithelial Sodium Channel

  2016cites this paper
• An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of pain

  2016cites this paper
• Engineering vanilloid-sensitivity into the rat TRPV2 channel

  2016cites this paper
• Caractérisation du canal cationique TRPV1 dans les cardiomyocytes

  2016cites this paper
• TRP Channels in Sensory Transduction

  2015cites this paper
• Biophysical and Molecular Features of Thermosensitive TRP Channels Involved in Sensory Transduction

  2015cites this paper
• Chemo-enzymatic tools to elucidate glycan-mediated TRPV5 regulation

  2015cites this paper
• Interaction between the L inker , PreS 1 , and TRP Domains Determines Folding , Assembly , and Trafficking of TRPV Channels Highlights

  2015cites this paper
• The heterogeneity of TRPV1 and its activation in nociceptive neurons

  2015cites this paper
• Pharmacology of TRP Channels

  2015cites this paper
• Perceptual Mapping of Chemesthetic Stimuli in Naive Assessors

  2015cites this paper
• The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating.

  2015cites this paper
• Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.

  2015cites this paper
• Herpes Simplex Virus Vector-Mediated Gene Delivery of Poreless TRPV1 Channels Reduces Bladder Overactivity and Nociception in Rats

  2015cites this paper
• Supraspinal Transient Receptor Potential Subfamily V Member 1 (TRPV1) in Pain and Psychiatric Disorders.

  2015cites this paper
• Transient receptor potential channels in the vasculature.

  2015cites this paper
• Mother root of Aconitum carmichaelii Debeaux exerts antinociceptive effect in Complet Freund’s Adjuvant-induced mice: roles of dynorpin/kappa-opioid system and transient receptor potential vanilloid type-1 ion channel

  2015cites this paper
• The influence of personality and experience on the perception, liking, and intake of spicy foods

  2014cites this paper
• The Region Adjacent to the C-end of the Inner Gate in Transient Receptor Potential Melastatin 8 (TRPM8) Channels Plays a Central Role in Allosteric Channel Activation*

  2014cites this paper
• Lipid modulation of thermal transient receptor potential channels.

  2014cites this paper
• Trafficking of ThermoTRP Channels

  2014cites this paper
• What do we really know and what do we need to know: some controversies, perspectives, and surprises.

  2014cites this paper
• Mechanoelektrische Transduktion in Sinneszellen des Chordotonalorgans

  2014cites this paper
• Targeting the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Assembly Domain Attenuates Inflammation-induced Hypersensitivity*

  2014cites this paper
• Domain Attenuates Inflammation-induced Vanilloid Type 1 ( TRPV 1 ) Assembly Targeting the Transient Receptor Potential Neurobiology :

  2014cites this paper
• The Transient Receptor Potential Vanilloid-1 Channel and Neuronal Survival in Degenerative Disease

  2014cites this paper
• Structural, biochemical and computational studies of TRP channel transmembrane domain modularity

  2014cites this paper
• Investigation of vascular dysfunction in pre-clinical models of sepsis

  2014cites this paper
• Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation

  2014cites this paper
• Structure of thermally activated TRP channels.

  2014influential citation
• Dissecting Domain-Specific Evolutionary Pressure Profiles of Transient Receptor Potential Vanilloid Subfamily Members 1 to 4

  2014cites this paper
• Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel.

  2014influential citation
• Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel – an overview of the current mutational data

  2013cites this paper
• Molecular Bases of Multimodal Regulation of a Fungal Transient Receptor Potential (TRP) Channel*

  2013cites this paper
• Heterologous expression and purification of an active human TRPV3 ion channel

  2013cites this paper
• Molecular mechanism of TRP channels.

  2013cites this paper
• Resonance Energy Transfer Channel Determined by Fluorescence Ion Receptor Potential Vanilloid 1 (TRPV1) Coarse Architecture of the Transient

  2013cites this paper
• Role of the C-terminal domain in the structure and function of tetrameric sodium channels

  2013cites this paper
• , Yohei ( TRP ) Channel of a Fungal Transient Receptor Potential Molecular Bases of Multimodal Regulation

  2013cites this paper
• What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel?

  2013cites this paper
• The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression.

  2013cites this paper
• Coarse Architecture of the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel Determined by Fluorescence Resonance Energy Transfer*

  2013cites this paper
• Investigation of the transient receptor potential vanilloid 1 (TRPV1) ion channel

  2013cites this paper
• TRPV 1 : a stress response protein in the central nervous system

  2012cites this paper
• 6.4 Biophysics of TRP Channels

  2012cites this paper
• Conservation of Tubulin-Binding Sequences in TRPV1 throughout Evolution

  2012cites this paper
• Receptor and Channel Heteromers as Pain Targets

  2012cites this paper