Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Development

• Publication date

  2001-12-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11748146
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intercellular signals regulating pancreas development and function.

  2001cited by this paper
• A bipotential precursor population for pancreas and liver within the embryonic endoderm.

  2001cited by this paper
• Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages.

  2000cited by this paper
• Control of endodermal endocrine development by Hes-1

  2000cited by this paper
• Attenuation of FGF signalling in mouse β-cells leads to diabetes

  2000cited by this paper
• neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.

  2000cited by this paper
• Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.

  2000cited by this paper
• The molecular basis of lung morphogenesis.

  2000cited by this paper
• Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.

  2000cited by this paper
• Regulation of pancreas development by hedgehog signaling.

  2000cited by this paper
• An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.

  2000cited by this paper
• Attenuation of FGF signalling in mouse beta-cells leads to diabetes.

  2000cited by this paper
• Pancreas: how to get there from the gut?

  1999cited by this paper
• Vertebrate endoderm development.

  1999cited by this paper
• Analysis of pancreatic development using a cell lineage label.

  1999cited by this paper
• Fgf10 is essential for limb and lung formation

  1999influential reference
• Morphogenesis.

  1999cited by this paper
• Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.

  1999cited by this paper
• Genetic control of branching morphogenesis.

  1999cited by this paper
• Notch signalling controls pancreatic cell differentiation

  1999influential reference
• Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless.

  1998cited by this paper
• Sonic hedgehog is essential to foregut development

  1998cited by this paper
• Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development.

  1998cited by this paper
• Sonic hedgehog regulates branching morphogenesis in the mammalian lung.

  1998cited by this paper
• The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.

  1998cited by this paper
• sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

  1998cited by this paper
• Transcribing pancreas.

  1998cited by this paper
• Pattern formation in epithelial development: the vertebrate limb and feather bud spacing.

  1998cited by this paper
• Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas.

  1997cited by this paper
• Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

  1997cited by this paper
• Fibroblast Growth Factor 10 ( FGF 10 ) and branching morphogenesis in the embryonic mouse lung

  1997cited by this paper
• Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung.

  1997influential reference
• Notochord to endoderm signaling is required for pancreas development.

  1997cited by this paper
• PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.

  1996cited by this paper
• The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice.

  1996cited by this paper
• Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors.

  1996cited by this paper
• Models of biological pattern formation: common mechanism in plant and animal development.

  1996cited by this paper
• Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.

  1995cited by this paper
• Developmental biology of the pancreas.

  1995cited by this paper
• Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal‐epithelial interactions

  1995cited by this paper
• Insulin-promoter-factor 1 is required for pancreas development in mice

  1994cited by this paper
• IPF1, a homeodomain‐containing transactivator of the insulin gene.

  1993cited by this paper
• Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2).

  1993cited by this paper
• Polyclonal origin of pancreatic islets in aggregation mouse chimaeras.

  1991cited by this paper
• [The biology of the pancreas].

  1987cited by this paper
• An ultrastructural analysis of the developing embryonic pancreas.

  1972influential reference
• Early Pancreas Organogenesis: Morphogenesis, Tissue Interactions, and Mass Effects.

  1967cited by this paper
• Epitheliomesenchymal interaction in pancreatic morphogenesis.

  1962influential reference

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• Fibroblast growth factor 10.

  2023cites this paper
• Bone marrow stem cell-derived β-cells: New issue for diabetes cell therapy.

  2023cites this paper
• Gene Enrichment Analysis of Dental Cavities Associated Human Genes

  2023cites this paper
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  2023influential citation
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  2023cites this paper
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  2023cites this paper
• Stem Cell Therapy for the Management of Type 1 Diabetes: Advances and Perspectives.

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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
• Exocrine gland structure-function relationships.

  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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