Inadequate heat release from the human brain during prolonged exercise with hyperthermia

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Physiology

• Publication date

  2002-12-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1113/jphysiol.2002.030023PMID 12456844PMCID PMC2290690
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004cited by this paper
• Enhanced brain protection during passive hyperthermia in humans

  2004cited by this paper
• Tympanic temperatures during hemiface cooling

  2004cited by this paper
• Effects of hyperthermia on cerebral blood flow and metabolism during prolonged exercise in humans.

  2002influential reference
• Hyperthermia and central fatigue during prolonged exercise in humans.

  2001cited by this paper
• Effects of marked hyperthermia with and without dehydration on VO(2) kinetics during intense exercise.

  2001cited by this paper
• Middle cerebral artery blood velocity is reduced with hyperthermia during prolonged exercise in humans

  2001cited by this paper
• Coupling between changes in human brain temperature and oxidative metabolism during prolonged visual stimulation

  2000influential reference
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  2000cited by this paper
• Coupling between changes in human brain temperature and oxidative metabolism during prolonged visual stimulation.

  2000cited by this paper
• Thermoregulatory effects of three different types of head cooling in humans during a mild hyperthermia

  2000cited by this paper
• Cerebral blood flow and metabolism during exercise.

  2000cited by this paper
• CEREBRAL BLOOD FLOW AND METABOLISM DURING EXERCISE

  1999cited by this paper
• Influence of body temperature on the development of fatigue during prolonged exercise in the heat.

  1999cited by this paper
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  1999cited by this paper
• Brain temperature and limits on transcranial cooling in humans: quantitative modeling results

  1998cited by this paper
• Failure of localized head cooling to reduce brain temperature in adult humans

  1998cited by this paper
• Brain and abdominal temperatures at fatigue in rats exercising in the heat.

  1998cited by this paper
• Functional imaging of the brain by infrared radiation (thermoencephaloscopy).

  1998influential reference
• Selective brain cooling in hyperthermia: the mechanisms and medical implications.

  1998cited by this paper
• Quantification of anaerobic energy production during intense exercise.

  1998cited by this paper
• Selective brain cooling in humans: “fancy” or fact?

  1993influential reference
• Middle cerebral artery blood velocity and cerebral blood flow and O2 uptake during dynamic exercise.

  1993influential reference
• Human circulatory and thermoregulatory adaptations with heat acclimation and exercise in a hot, dry environment.

  1993cited by this paper
• Specialized brain cooling in humans?

  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
• Changes in human intracerebral temperature in response to different methods of brain cooling.

  1992cited by this paper
• Evidence against brain stem cooling by face fanning in severely hyperthermic humans

  1992cited by this paper
• Heat loss from the human head during exercise.

  1991cited by this paper
• Tympanic temperature is a core temperature in humans

  1989cited by this paper
• Independence of brain and tympanic temperatures in an unanesthetized human.

  1988cited by this paper
• Effects of brain and trunk temperatures on exercise performance in goats

  1986cited by this paper
• Normal Average Value of Cerebral Blood Flow in Younger Adults is 50 ml/100 g/min

  1985cited by this paper
• Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries.

  1982cited by this paper
• Natural selective cooling of the human brain: evidence of its occurrence and magnitude.

  1979cited by this paper
• Respiratory heat loss at increased core temperature.

  1974cited by this paper
• Common carotid blood temperature.

  1960cited by this paper
• Cerebral circulation and metabolism in pulmonary emphysema and fibrosis with observations on the effects of mild exercise.

  1953influential reference
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  1948influential reference
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  1948cited by this paper
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  1948cited by this paper

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  2024influential citation
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  2023cites this paper
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