BID‐dependent release of mitochondrial SMAC dampens XIAP‐mediated immunity against Shigella

No abstract is available for this paper.

• Publication year

  2014

• Venue

  EMBO Journal

• Publication date

  2014-07-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.15252/embj.201387244PMID 25056906PMCID PMC4282505
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
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  2004cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1998cited by this paper
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  1998influential reference
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  1996cited by this paper
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  2017cites this paper
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  2017cites this paper
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