Novel Stem/Progenitor Cell Population from Murine Tracheal Submucosal Gland Ducts with Multipotent Regenerative Potential

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Stem Cells

• Publication date

  2011-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/stem.680PMID 21710468PMCID PMC3403816
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A single cell functions as a tissue-specific stem cell and the in vitro niche-forming cell.

  2011cited by this paper
• Context-dependent differentiation of multipotential keratin 14-expressing tracheal basal cells.

  2011cited by this paper
• Evidence for human lung stem cells.

  2011cited by this paper
• Evidence for human lung stem cells.

  2011cited by this paper
• Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix.

  2011cited by this paper
• Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung

  2010cited by this paper
• Keratin promoter based gene manipulation in the murine conducting airway

  2010cited by this paper
• Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.

  2010influential reference
• Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.

  2009cited by this paper
• Basal cells as stem cells of the mouse trachea and human airway epithelium

  2009influential reference
• The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium.

  2009cited by this paper
• Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

  2008cited by this paper
• Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

  2008cited by this paper
• Innate immune functions of the airway epithelium.

  2008cited by this paper
• Label-retaining Cells in the Rat Submandibular Gland

  2008cited by this paper
• Circulating Progenitor Epithelial Cells Traffic via CXCR4/CXCL12 in Response to Airway Injury1

  2006cited by this paper
• Generation of a functional mammary gland from a single stem cell

  2006cited by this paper
• Intercellular growth factor signaling and the development of mouse tracheal submucosal glands

  2005influential reference
• A subset of mouse tracheal epithelial basal cells generates large colonies in vitro.

  2004cited by this paper
• Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium.

  2004cited by this paper
• In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations.

  2004cited by this paper
• New insights into saccular development and vascular formation in lung allografts under the renal capsule.

  2003cited by this paper
• The kinetics and pattern of tracheal allograft re-epithelialization.

  2003cited by this paper
• In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme

  2003cited by this paper
• Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.

  2002cited by this paper
• Evidence for stem-cell niches in the tracheal epithelium.

  2001cited by this paper
• Progenitor cells of the adult human airway involved in submucosal gland development.

  1995cited by this paper
• Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.

  1992cited by this paper
• The differentiation potential of tracheal basal cells.

  1988cited by this paper
• A reconstruction of the duct system and secretory tubules of the human bronchial submucosal gland

  1969cited by this paper
• Rapid In Vivo Retroviral Gene Transfer into Human Bronchial Epithelia of Xenografts

  year unknowncited by this paper

• Role of Homeobox A1 in Airway Epithelial Generation from Human Airway Basal Cells

  2025cites this paper
• Human airway submucosal gland organoids to study respiratory inflammation and infection.

  2025cites this paper
• Porcine airway tissue explant culture at a hydrogel-air interface to model submucosal glands in cystic fibrosis progression and therapy

  2025cites this paper
• A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma

  2025cites this paper
• Ferrostatin-1 inhibits tracheal basal cell ferroptosis to facilitate the rapid epithelization of 3D-printed tissue-engineered tracheas

  2025cites this paper
• Cell–cell interactions and communication dynamics in lung fibrosis

  2024cites this paper
• Lung repair and regeneration: Advanced models and insights into human disease.

  2024cites this paper
• Regenerative medicine in lung diseases: A systematic review

  2023cites this paper
• Lung Development in a Dish: Models to Interrogate the Cellular Niche and the Role of Mechanical Forces in Development.

  2023cites this paper
• Three-dimensional models of the lung: past, present and future: a mini review.

  2022cites this paper
• Morpho‐functional characterization of the submucosal glands at the nasopharyngeal end of the auditory tube in humans

  2022cites this paper
• A spatially resolved atlas of the human lung characterizes a gland-associated immune niche

  2022cites this paper
• Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells

  2022cites this paper
• Pulmonary endogenous progenitor stem cell subpopulation: Physiology, pathogenesis, and progress

  2022influential citation
• Biobanked tracheal basal cells retain the capacity to differentiate

  2022cites this paper
• Roles of airway basal stem cells in lung homeostasis and regenerative medicine

  2022cites this paper
• Sox9 and Lef1 regulate the fate and behavior of airway glandular progenitors in response to injury.

  2022cites this paper
• Lung epithelium development and airway regeneration

  2022cites this paper
• A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche

  2021cites this paper
• Molecular crosstalk in tracheal development and its recurrence in adult tissue regeneration

  2021cites this paper
• Stem cells of submucosal glands: their function as tissue stem cells and a reserve population for airway repair

  2021cites this paper
• The diversity of adult lung epithelial stem cells and their niche in homeostasis and regeneration

  2021cites this paper
• Dorso-ventral heterogeneity in tracheal basal stem cells

  2021cites this paper
• Decreased production of epithelial-derived antimicrobial molecules at mucosal barriers during early life

  2021cites this paper
• Transcriptomic Analysis of Polyhexamethyleneguanidine-Induced Lung Injury in Mice after a Long-Term Recovery

  2021influential citation
• Lung Regeneration: Cells, Models, and Mechanisms.

  2021cites this paper
• A census of the lung: CellCards from LungMAP.

  2021cites this paper
• Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration.

  2020cites this paper
• Stem Cells and Lung Regeneration.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Stem Cell-Based Therapy for Lung Disease

  2019cites this paper
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  2019cites this paper
• Cell-based therapy for idiopathic pulmonary fibrosis.

  2019cites this paper
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  2019cites this paper
• Stem Cells Heterogeneity in Different Organs

  2019cites this paper
• Electrospun scaffolds limit the regenerative potential of the airway epithelium

  2019cites this paper
• Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

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• Buried myoepithelial stem cells as a reservoir for repairing the exposed airway epithelium.

  2018cites this paper
• Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2015cites this paper
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  2015cites this paper
• Identification of cholinergic chemosensory cells in mouse tracheal and laryngeal glandular ducts.

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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
• Clonal culture of adult mouse lung epithelial stem/progenitor cells.

  2015cites this paper
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  2015influential citation
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  2015cites this paper
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  2015cites this paper
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