13-cis-retinoic acid and interferon alpha-2a: effective combination therapy for advanced squamous cell carcinoma of the skin.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Journal of the National Cancer Institute

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 1734084
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients.

  1991cited by this paper
• Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid).

  1991cited by this paper
• Antiproliferative activity of retinoids, interferon alpha and their combination in five human transformed cell lines.

  1991cited by this paper
• Potentiation of retinoid-induced differentiation of HL-60 and U937 cell lines by cytokines.

  1991cited by this paper
• Enhancement by retinoic acid and dibutyryl cyclic adenosine 3':5'-monophosphate of the differentiation and gene expression of human neuroblastoma cells induced by interferon.

  1991cited by this paper
• Biomarkers as intermediate end points in chemoprevention trials.

  1990cited by this paper
• Modulation of epidermal growth factor receptors by retinoic acid in ME180 cells.

  1990cited by this paper
• Interferons: a new class of tumor suppressor genes?

  1990cited by this paper
• TGF-beta: problems and prospects.

  1990cited by this paper
• Cisplatin-based chemotherapy in advanced basal and squamous cell carcinomas of the skin: results in 28 patients including 13 patients receiving multimodality therapy.

  1990cited by this paper
• Treatment of advanced squamous cell carcinoma of the skin with cisplatin, 5‐fluorouracil, and bleomycin

  1990cited by this paper
• Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review.

  1990cited by this paper
• Comprehensive criteria for assessing therapy-induced toxicity.

  1990cited by this paper
• Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck.

  1990cited by this paper
• Results of the use of vitamin A and retinoids in cutaneous malignancies.

  1989cited by this paper
• The role of polyamines in interferon and retinoic acid mediated synergistic antiproliferative action.

  1989cited by this paper
• Interaction of interferon with other cytokines

  1989cited by this paper
• Interferon receptors and their role in interferon action

  1989cited by this paper
• Retinoid receptor antisense DNAs inhibit alkaline phosphatase induction and clonogenicity in malignant keratinocytes.

  1989cited by this paper
• Successful treatment of an angiogenic disease.

  1989cited by this paper
• Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin.

  1988cited by this paper
• The role of interferon in cancer therapy: A current perspective

  1988cited by this paper
• Inhibition of angiogenesis through modulation of collagen metabolism.

  1988cited by this paper
• The steroid and thyroid hormone receptor superfamily.

  1988cited by this paper
• Basal cell carcinoma and squamous cell carcinoma. Recognition and treatment.

  1988cited by this paper
• Interferon receptors.

  1988cited by this paper
• Antitumor Actions of Interferons

  1987cited by this paper
• Retinoids as preventive and therapeutic anticancer agents (Part II).

  1987cited by this paper
• Treatment of advanced squamous cell carcinoma of the skin with isotretinoin.

  1987cited by this paper
• Interferons and their actions.

  1987cited by this paper
• Effects of interferon and retinoic acid on the growth and differentiation of clonogenic leukemic cells from acute myelogenous leukemia patients treated with recombinant leukocyte-alpha A interferon.

  1987cited by this paper
• Combinations of recombinant human interferons and retinoic acid synergistically induce differentiation of the human promyelocytic leukemia cell line HL-60.

  1987cited by this paper
• Retinoids as preventive and therapeutic anticancer agents (Part I).

  1987cited by this paper
• 13-cis-retinoic acid in the treatment of oral leukoplakia.

  1986cited by this paper
• Synergistic antiproliferative effect of human recombinant interferons and retinoic acid in cultured breast cancer cells.

  1986cited by this paper
• Clinical studies of recombinant interferon alfa‐2a (Roferon®‐A) in cancer patients

  1986cited by this paper
• Mechanism of action of retinoids.

  1986cited by this paper
• Alpha interferon for induction of remission in hairy-cell leukemia.

  1984cited by this paper
• Vitamin A and retinoids: from nutrition to pharmacotherapy in dermatology and oncology.

  1983cited by this paper
• Recombinant leukocyte A interferon: pharmacokinetics, single-dose tolerance, and biologic effects in cancer patients.

  1982cited by this paper
• Combination chemotherapy of head and neck cancer

  1978cited by this paper
• Squamous Cell and Basal Cell Carcinomas: Preliminary Study of 3,817 Primary Skin Cancers

  1978cited by this paper
• The determinatio of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent.

  1961cited by this paper

• Isotretinoin as a Multifunctional Anticancer Agent: Molecular Mechanisms, Pharmacological Insights and Therapeutic Potential

  2025cites this paper
• Isotretinoin Treatment for Acne Vulgaris: A Five-Year Retrospective Analysis of Clinical and Biochemical Adverse Effects

  2025cites this paper
• Medikamentöse Therapie von malignen Lidtumoren

  2024cites this paper
• The relationship between blood vitamin A levels and diabetic retinopathy: a population-based study

  2024cites this paper
• Structure–Activity Relationships and Therapeutic Applications of Retinoids in View of Potential Benefits from Drug Repurposing Process

  2024cites this paper
• Medikamentöse Therapie von malignen Lidtumoren

  2024cites this paper
• Oral Isotretinoin and Its Uses in Dermatology: A Review

  2023cites this paper
• Successful management of hydroxyurea‐induced multiple actinic keratoses and cutaneous squamous cell carcinomas with combination treatment

  2023cites this paper
• Advances in Cutaneous Squamous Cell Carcinoma Management

  2022cites this paper
• Management of elderly patients with advanced cutaneous squamous cell carcinoma.

  2022cites this paper
• The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review

  2022cites this paper
• Molecular and immune targets in cutaneous squamous cell carcinoma

  2022cites this paper
• A prospective study investigating the efficacy and toxicity of definitive ChemoRadiation and ImmunOtherapy (CRIO) in locally and/or regionally advanced unresectable cutaneous squamous cell carcinoma

  2021cites this paper
• Systemic acitretin in the management of periocular squamous cell carcinoma

  2021cites this paper
• Kutanes Plattenepithelkarzinom

  2020cites this paper
• Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

  2020cites this paper
• Cutaneous squamous cell carcinoma in the organ transplant recipient.

  2020cites this paper
• Oral isotretinoin for the treatment of dermatologic conditions other than acne: a systematic review and discussion of future directions

  2020cites this paper
• Update on the Management of Cutaneous Squamous Cell Carcinoma

  2020cites this paper
• A Prospective Study Investigating the Efficacy and Toxicity of Definitive ChemoRadadiation and ImmunOtherapy (CRIO) in Locally and/or Regionally Advanced Cutaneous Squamous Cell Carcinoma.

  2020cites this paper
• Review of systemic agents in the treatment of advanced cutaneous squamous cell carcinoma.

  2019cites this paper
• Uncommon Presentation of Metastatic Squamous Cell Carcinoma of the Skin and Treatment Challenges

  2019cites this paper
• Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial

  2019cites this paper
• Metastatic porocarcinoma achieving complete radiological and clinical response with pembrolizumab

  2019cites this paper
• Immunotherapy and other systemic therapies for cutaneous SCC.

  2019cites this paper
• Medical treatment of advanced cutaneous squamous‐cell carcinoma

  2019cites this paper
• Efficiency of All-Trans Retinoic Acid on Gastric Cancer: A Narrative Literature Review

  2018cites this paper
• Cutaneous squamous cell carcinoma. Italian Guidelines by SIDeMaST adapted to and updating EADO/EDF/EORTC guidelines.

  2018cites this paper
• Non-melanoma skin cancer: new and future synthetic drug treatments

  2017cites this paper
• Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells.

  2017cites this paper
• Retinoic acid ameliorates photoaged skin through RAR‑mediated pathway in mice.

  2017cites this paper
• Recurrent squamous cell carcinoma of the skin treated successfully with single agent cetuximab therapy

  2016cites this paper
• Systemic Therapy in Advanced Cutaneous Squamous Cell Carcinoma (CSCC): The Roswell Park Experience and a Review of the Literature

  2016cites this paper
• Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease

  2016cites this paper
• An apparently untreatable ulcer of the face

  2016cites this paper
• Development of Hemolytic Anemia in a Nivolumab-Treated Patient with Refractory Metastatic Squamous Cell Skin Cancer and Chronic Lymphatic Leukemia

  2016cites this paper
• Rising incidence and aggressive nature of cutaneous malignancies after transplantation: An update on epidemiology, risk factors, management and surveillance.

  2015cites this paper
• Retinoic acid receptors: from molecular mechanisms to cancer therapy.

  2015cites this paper
• Pharmacologic treatment options for advanced epithelial skin cancer

  2015cites this paper
• An overview of the medical management of nonmelanoma skin cancer.

  2015cites this paper
• Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline.

  2015cites this paper
• Interferon alpha plus 13-cis-retinoic acid modulation of BCL-2 plus paclitaxel for recurrent small-cell lung cancer (SCLC): an Eastern Cooperative Oncology Group study (E6501)

  2014cites this paper
• Unresectable perineal cuniculatum carcinoma: partial remission using systemic isotretinoin and interferon-α2a therapy.

  2014cites this paper
• Evidence based analysis of Cisplatin for treating patients with cutaneous squamous cell carcinoma.

  2014cites this paper
• Retinoic acid actions through mammalian nuclear receptors.

  2014cites this paper
• Updated Physician's Guide to the Off-label Uses of Oral Isotretinoin.

  2014cites this paper
• Epidermodysplasia verruciformis-symptoms , causes , diagnosis and treatment

  2014cites this paper
• Optimal treatment of unresectable nonmelanoma skin cancers.

  2014cites this paper
• Targeted therapy for cutaneous oncology: a review of novel treatment options for non-melanoma skin cancer: part II.

  2014cites this paper
• Oral S‐1 in advanced cutaneous squamous cell carcinoma

  2014cites this paper
• Phase 2 Trial of Paclitaxel, 13-cis Retinoic Acid, and Interferon Alfa-2b in the Treatment of Advanced Stage or Recurrent Cervical Cancer

  2014cites this paper
• Therapy of Advanced Squamous Cell Carcinoma of the Skin

  2014cites this paper
• Developments in the treatment of locally advanced and metastatic squamous cell carcinoma of the skin: a rising unmet need.

  2014cites this paper
• Tumor suppressor in lung cancer 1 (TSLC1), a novel tumor suppressor gene, is implicated in the regulation of proliferation, invasion, cell cycle, apoptosis, and tumorigenicity in cutaneous squamous cell carcinoma

  2013cites this paper
• DLC1 as a regulator of proliferation, invasion, cell cycle, and apoptosis in cutaneous squamous cell carcinoma

  2013cites this paper
• Brief S2k guidelines – Cutaneous squamous cell carcinoma

  2013cites this paper
• Retinol levels are associated with magnetic resonance imaging outcomes in multiple sclerosis

  2013cites this paper
• Platinum and anthracycline therapy for advanced cutaneous squamous cell carcinoma

  2013cites this paper
• Racial and Ethnic Differences in the Pathogenesis and Clinical Manifestations of Uterine Leiomyoma

  2013cites this paper
• Interventions for non-metastatic squamous cell carcinoma of the skin: systematic review and pooled analysis of observational studies

  2013cites this paper
• Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice

  2013cites this paper
• A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck

  2012cites this paper
• New Oral Chemotherapeutic Agents for Lung Cancer

  2012cites this paper
• Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

  2012cites this paper
• Pegylated interferon-α-2b for children with recurrent craniopharyngioma.

  2012cites this paper
• Identification and functional activation of peroxisome proliferator-activated receptor in human upper aerodigestive cancer

  2012cites this paper
• Complete response of metastatic cutaneous squamous cell carcinoma to cetuximab plus paclitaxel.

  2012cites this paper
• Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.

  2012cites this paper
• Use of oral isotretinoin in the management of rosacea.

  2011cites this paper
• Systemic treatment of locally advanced nonmetastatic cutaneous squamous cell carcinoma: a review of the literature

  2011cites this paper
• Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin.

  2011cites this paper
• Locally Advanced Cutaneous Squamous Cell Carcinoma: Two Case Reports of Dramatic Responses to Sequential Cisplatin, Docetaxel and Radiotherapy

  2011cites this paper
• Metastatic cutaneous squamous cell carcinoma responding to erlotinib therapy.

  2011cites this paper
• Does Basal Cell Carcinoma Belong to the Spectrum of Sorafenib-Induced Epithelial Skin Cancers?

  2010cites this paper
• Treatment of unresectable and metastatic cutaneous squamous cell carcinoma.

  2010cites this paper
• Treatment of advanced, recurrent, resistant to previous treatments basal and squamous cell skin carcinomas with a synergistic formulation of interferons. Open, prospective study

  2009cites this paper
• Management of metastatic skin cancers in organ transplant recipients.

  2009cites this paper
• Effets des ligands de PPAR[gamma] sur la voie de signalisation des oestrogènes dans les cellules cancéreuses mammaires

  2009cites this paper
• Cyclin D1 and Cancer Development in Laryngeal Premalignancy Patients

  2009cites this paper
• Das Marjolin-Ulkus

  2009cites this paper
• Molecular events as targets of anticancer drug therapy

  2008cites this paper
• Head and neck cancer : an evidence-based team approach

  2008cites this paper
• Metastatic Cutaneous Squamous Cell Carcinoma: An Update

  2007cites this paper
• Off-label uses of biologics in dermatology: interferon and intravenous immunoglobulin (part 1 of 2).

  2007cites this paper
• Induction of cell cycle arrest and apoptosis by a combined treatment with 13-cis-retinoic acid, interferon-alpha2a, and alpha-tocopherol in squamous cell carcinoma of the head and neck.

  2007cites this paper
• [Marjolin's ulcer in chronic osteomyelitis: seven cases and a review of the literature].

  2007cites this paper
• Marjolin ’ s ulcer in chronic osteomyelitis : seven cases and a review of the literature Diagnostic et résultats du traitement : 7 cas

  2007cites this paper
• Randomized trial of adjuvant 13-cis-retinoic acid and interferon alfa for patients with aggressive skin squamous cell carcinoma.

  2007cites this paper
• A phase 2 trial of all‐trans‐retinoic acid in combination with interferon‐α2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch, NCI and Children's Oncology Group Study

  2007cites this paper
• A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch, NCI and Children's Oncology Group Study.

  2007cites this paper
• Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons.

  2007cites this paper
• Peroxisome proliferator-activated receptor gamma in malignant diseases.

  2006cites this paper
• Chemoprevention of squamous cell carcinoma of the oral cavity.

  2006cites this paper
• Randomized phase II/III trial of interferon Alfa-2a with and without 13-cis-retinoic acid in patients with progressive metastatic renal cell Carcinoma: the European Organisation for Research and Treatment of Cancer Genito-Urinary Tract Cancer Group (EORTC 30951).

  2005cites this paper
• Prospective, randomized, multicenter, double-blind placebo-controlled trial comparing adjuvant interferon alfa and isotretinoin with interferon alfa alone in stage IIA and IIB melanoma: European Cooperative Adjuvant Melanoma Treatment Study Group.

  2005cites this paper
• Tumorigenicity Issues of Embryonic Carcinoma-derived Stem Cells: Relevance to Surgical Trials Using NT2 and hNT Neural Cells

  2005cites this paper
• Phase II Study of All-trans-retinoic Acid and a-Interferon in Patients with Advanced Non-Small Cell Lung Cancer

  2005cites this paper
• Interferon alpha 2a downregulates VEGF expression through PI3 kinase and MAP kinase signaling pathways

  2005cites this paper
• The efficacy of 9-cis retinoic acid in experimental models of cancer

  2005cites this paper
• Huidkanker en andere huidaandoeningen bij patiënten na transplantatie van een solide orgaan

  2005cites this paper