The authors find that matrix metalloproteinase MT1-MMP is enriched at the plasma membrane of macrophage podosomes, where it persists beyond podosome lifetime and, through binding to the subcortical actin cytoskeleton, forms subcellular signposts that facilitate podosome reformation.
Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence
Karim El azzouzi,Christiane Wiesner,S. Linder
Published 2016 in Journal of Cell Biology
ABSTRACT
PUBLICATION RECORD
- Publication year
2016
- Venue
Journal of Cell Biology
- Publication date
2016-04-11
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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