Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Nature Genetics

• Publication date

  1998-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/1700PMID 9731529
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.

  1997cited by this paper
• Association of the mammalian helicase MAH with the pre-mRNA splicing complex.

  1997cited by this paper
• Cell biology and the genome projects a concerted strategy for characterizing multiprotein complexes by using mass spectrometry.

  1997cited by this paper
• Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer.

  1997cited by this paper
• The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p.

  1997cited by this paper
• Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

  1996cited by this paper
• Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels.

  1996cited by this paper
• Delayed extraction improves specificity in database searches by matrix-assisted laser desorption/ionization peptide maps.

  1996cited by this paper
• A Gene Map of the Human Genome

  1996cited by this paper
• The HeLa 200 kDa U5 snRNP‐specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH‐box protein family of putative RNA helicases.

  1996cited by this paper
• Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels.

  1996cited by this paper
• The structure and function of proteins involved in mammalian pre-mRNA splicing.

  1996cited by this paper
• Analytical properties of the nanoelectrospray ion source.

  1996cited by this paper
• Nuclear Pre-mRNA Splicing

  1995cited by this paper
• A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor (*)

  1995cited by this paper
• Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry.

  1995cited by this paper
• Yeast Splicing Factors and Genetic Strategies for Their Analysis

  1995cited by this paper
• Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22

  1994cited by this paper
• Error-tolerant identification of peptides in sequence databases by peptide sequence tags.

  1994cited by this paper
• Splicing of precursors to mRNAs by the spliceosomes

  1993cited by this paper
• Protein components specifically associated with prespliceosome and spliceosome complexes.

  1992cited by this paper
• Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

  1992cited by this paper
• Protein composition of mammalian spliceosomes assembled in vitro.

  1990cited by this paper
• Birth of the D-E-A-D box

  1989cited by this paper
• Purification and visualization of native spliceosomes.

  1988cited by this paper
• Nuclear protein with sequence homology to translation initiation factor eIF-4A

  1988cited by this paper
• High resolution two-dimensional electrophoresis of basic as well as acidic proteins.

  1977cited by this paper

• RBM17 Promotes the Chemoresistance of Oral Squamous Cancer Cells Through Checkpoint Kinase 1

  2025cites this paper
• Mutations in the spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly

  2025cites this paper
• BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus

  2025cites this paper
• The role of Arabidopsis Splicing Factor 30 in floral transition and the implications of its alternative splicing

  2025cites this paper
• m6A modification of CDC5L promotes lung adenocarcinoma progression through transcriptionally regulating WNT7B expression.

  2024cites this paper
• RBM17 Expression Is Associated With the Efficacy of ICI Monotherapy in NSCLC With Low PD-L1 Expression

  2023cites this paper
• Molecular characterization, expression patterns and cellular localization of BCAS2 gene in male Hezuo pig

  2023cites this paper
• Downregulation of RBM17 enhances cisplatin sensitivity and inhibits cell invasion in human hypopharyngeal cancer cells

  2023cites this paper
• Overexpression of TCERG1 as a prognostic marker in hepatocellular carcinoma: A TCGA data-based analysis

  2022cites this paper
• AKT1 phosphorylates RBM17 to promote Sox2 transcription by modulating alternative splicing of FOXM1 to enhance cancer stem cell properties in colorectal cancer cells

  2022cites this paper
• DNA and RNA Binding Proteins: From Motifs to Roles in Cancer

  2022cites this paper
• Activation of ERK by altered RNA splicing in cancer

  2022cites this paper
• Regulation of DEAH-box RNA helicases by G-patch proteins

  2021cites this paper
• USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis

  2021cites this paper
• Subcellular Transcriptomics and Proteomics: A Comparative Methods Review

  2021cites this paper
• IK: A novel cell mitosis regulator that contributes to carcinogenesis

  2021cites this paper
• Comparative transcriptome analysis of long non coding RNA (lncRNA) in RTG-2 cells infected by infectious hematopoietic necrosis virus.

  2021cites this paper
• Plant Proteomics and Systems Biology.

  2021cites this paper
• BCAS2 is involved in alternative splicing and mouse oocyte development

  2021cites this paper
• Blocking Osa‐miR1871 enhances rice resistance against Magnaporthe oryzae and yield

  2021cites this paper
• The mechanical regulation of RNA binding protein hnRNPC in the failing heart

  2021cites this paper
• Subcellular proteomics

  2021cites this paper
• Alternative splicing regulation of cell-cycle genes by SPF45/SR140/CHERP complex controls cell proliferation

  2021cites this paper
• Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2.

  2021cites this paper
• Exploration of the effects of the CYCLOPS gene RBM17 in hepatocellular carcinoma

  2020cites this paper
• Depletion of CDC5L inhibits bladder cancer tumorigenesis

  2020cites this paper
• Proteomic analysis of Trypanosoma cruzi spliceosome complex.

  2020cites this paper
• The general splicing factor SPF45 (RBM17) replaces the U2AF heterodimer in a distinct subset of human short introns

  2020cites this paper
• SPF45/RBM17-dependent, but not U2AF-dependent, splicing in human short introns

  2020cites this paper
• Comprehensive nuclear proteome of Arabidopsis obtained by sequential extraction

  2019cites this paper
• Role of TDP-43 and hnRNP proteins in the regulation of different RNA targets

  2019cites this paper
• The splicing component ISY1 regulates APE1 in base excision repair.

  2019cites this paper
• Role for the splicing factor TCERG1 in Cajal body integrity and snRNP assembly

  2019cites this paper
• Identification, evolution and alternative splicing profile analysis of the splicing factor 30 (SPF30) in plant species

  2019cites this paper
• A Distinct Subset of Human Short Introns: U2AF Heterodimer Is Replaced by SPF45 (RBM17) as General Splicing Factor

  2019cites this paper
• SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

  2019cites this paper
• H3K36 Methylation and the Chromodomain Protein Eaf3 Are Required for Proper Cotranscriptional Spliceosome Assembly

  2019cites this paper
• RBM-5 modulates U2AF large subunit-dependent alternative splicing in C. elegans

  2018cites this paper
• RBM17 controls apoptosis and proliferation to promote Glioma progression.

  2018cites this paper
• A systems view of spliceosomal assembly and branchpoints with iCLIP

  2018cites this paper
• RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins

  2018cites this paper
• Data and -omics-driven approaches to understand the heat stress response: the development of scalable tools and methods to drive hypothesis generation

  2018cites this paper
• Overexpression of SbSKIP, A Pre-mRNA splicing factor from Sorghum bicolor, enhances root growth and drought tolerance in Petunia hybrida

  2018cites this paper
• Downregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cells

  2018cites this paper
• The novel cyst nematode effector protein 30D08 targets host nuclear functions to alter gene expression in feeding sites.

  2018influential citation
• Characterisation of the whole-genome wide hexokinase gene family unravels the functional divergence in pear (Pyrus bretschneideri Rehd.)

  2018cites this paper
• Understanding Leishmania parasites through proteomics and implications for the clinic

  2018cites this paper
• Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

  2018cites this paper
• Regulação pós-transcricional da enzima glutaminase por HuR e sua relação com os altos níveis glutaminolíticos tumorais = Post-transcriptional regulation of glutaminase enzyme by HuR and its relationship with high glutaminolytic levels in tumors

  2018cites this paper
• SNW1 (SNW domain containing 1)

  2018cites this paper
• Fragile X mental retardation protein recognizes a G quadruplex structure within the survival motor neuron domain containing 1 mRNA 5'-UTR.

  2017cites this paper
• Methods, Tools and Current Perspectives in Proteogenomics *

  2017cites this paper
• SPF45-related splicing factor for phytochrome signaling promotes photomorphogenesis by regulating pre-mRNA splicing in Arabidopsis

  2017influential citation
• Proteomic Applications of Polymeric Nanoparticles with Engineered Affinity towards Select Target

  2017cites this paper
• The role of Drosophila Bx42/SKIP in cell cycle

  2017cites this paper
• Insights into protein-RNA complexes from computational analyses of iCLIP experiments

  2017cites this paper
• Human MFAP1 is a cryptic ortholog of the Saccharomyces cerevisiae Spp381 splicing factor

  2017cites this paper
• Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNA-Binding Protein Syncrip

  2017cites this paper
• Expression of CDC5L is associated with tumor progression in gliomas

  2016cites this paper
• Protein mechanisms in response to NaCl-stress of salt-tolerant and salt-sensitive industrial hemp based on iTRAQ technology

  2016cites this paper
• XXVIII Cycle “ Functional analysis of Dnajc 17 gene function : in vivo and in vitro studies

  2016cites this paper
• Study of genetic factors and temperature influence on sex determination and differentiation in turbot

  2016cites this paper
• Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation.

  2016cites this paper
• Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models.

  2016cites this paper
• Molecular recognition of splicing factors involved in Fas alternative splicing

  2016cites this paper
• Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.

  2016cites this paper
• Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication

  2016cites this paper
• The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub*

  2015cites this paper
• Genome-wide Analysis of Groucho Function in Drosophila Embryogenesis

  2015cites this paper
• Methylarginine recognition by tudor domains

  2015cites this paper
• Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

  2015cites this paper
• Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response

  2015cites this paper
• BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development

  2015cites this paper
• An Investigation of the Regulation of RNA Polymerase II Transcription Termination by SMN, FUS, and TDP-43 in a pathway involving Symmetric Arginine Dimethylation (R1810) of the RNAPII CTD

  2015cites this paper
• The influence of Argonaute proteins on alternative RNA splicing

  2015cites this paper
• Incorporating significant amino acid pairs and protein domains to predict RNA splicing-related proteins with functional roles

  2014cites this paper
• Role of the OB-fold of RNA helicase A in the synthesis of HIV-1 RNA.

  2014cites this paper
• Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe

  2014cites this paper
• Readers of histone methylarginine marks.

  2014cites this paper
• Splicing of Receptor-Like Kinase-Encoding SNC4 and CERK1 is Regulated by Two Conserved Splicing Factors that Are Required for Plant Immunity

  2014cites this paper
• Mediators of pre-mRNA splicing regulate sister chromatid cohesion in mammalian cells

  2014cites this paper
• The influence of Argonaute proteins on alternative RNA

  2014cites this paper
• Quantitative Proteomics by SWATH-MS Reveals Altered Expression of Nucleic Acid Binding and Regulatory Proteins in HIV-1-Infected Macrophages

  2014cites this paper
• Recruitment of RED-SMU1 Complex by Influenza A Virus RNA Polymerase to Control Viral mRNA Splicing

  2014cites this paper
• SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre‐mRNAs

  2014cites this paper
• Poly(A) RNA‐binding proteins and polyadenosine RNA: new members and novel functions

  2014cites this paper
• Preventing Prostate Cancer Metastasis by Targeting Exosome Secretion

  2014cites this paper
• A day in the life of the spliceosome

  2014cites this paper
• The SPF27 Homologue Num1 Connects Splicing and Kinesin 1-Dependent Cytoplasmic Trafficking in Ustilago maydis

  2014cites this paper
• Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion

  2013cites this paper
• Nuclear protein IK undergoes dynamic subcellular translocation and forms unique nuclear bodies during the cell cycle

  2013cites this paper
• Transcriptome Analysis of Newt Lens Regeneration Reveals Distinct Gradients in Gene Expression Patterns

  2013cites this paper
• “Stainomics”: Identification of mitotracker labeled proteins in mammalian cells

  2013cites this paper
• Innovation in Technology development with reference to enzymatic extraction of flavonoids.

  2013cites this paper
• Untersuchung von multivalenten Protein-Protein Interaktionen zwischen WW-Domänen und prolinreichen Sequenzen

  2013cites this paper
• Affinity purification of spliceosomal and small nuclear ribonucleoprotein complexes.

  2013cites this paper
• BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing.

  2013cites this paper
• DNA repair mechanisms and Toxoplasma gondii infection

  2013cites this paper
• Regulation of Fasciclin II and Synaptic Terminal Development by the Splicing Factor Beag

  2012cites this paper
• The Role of Polypyrimidine Tract-Binding Proteins and Other hnRNP Proteins in Plant Splicing Regulation

  2012cites this paper