Botulinum neurotoxins for post‐stroke spasticity in adults: A systematic review

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Movement Disorders

• Publication date

  2009-04-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/mds.22452PMID 19224614
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy (UPDATE).

  2010cited by this paper
• Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review) Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

  2008cited by this paper
• Assessment: Botulinum neurotoxin for the treatment of spasticity (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologySYMBOL

  2008cited by this paper
• Early communication about an ongoing safety review Botox and Botox Cosmetic (botulinum toxin type A) and Myobloc (botulinum toxin type B).

  2008cited by this paper
• Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after stroke.

  2007influential reference
• Comparing two botulinum toxin type A formulations using manufacturers’ product summaries

  2007cited by this paper
• Botulinum Toxin Treatment of Adult Spasticity

  2006cited by this paper
• Clinical use of non-a botulinum toxins: botulinum toxin type B

  2006cited by this paper
• Improvements in healthcare and cost benefits associated with botulinum toxin treatment of spasticity and muscle overactivity

  2006cited by this paper
• Secondary nonresponsiveness to botulinum toxin A in cervical dystonia: The role of electromyogram‐guided injections, botulinum toxin A antibody assay, and the extensor digitorum brevis test

  2006cited by this paper
• Pooled analysis of the safety of botulinum toxin type A in the treatment of poststroke spasticity.

  2006cited by this paper
• The lowest effective dose of botulinum A toxin in adult patients with upper limb spasticity

  2005influential reference
• Clinical scales for the assessment of spasticity, associated phenomena, and function: a systematic review of the literature

  2005cited by this paper
• A randomized controlled trial of botulinum toxin on lower limb spasticity following acute acquired severe brain injury

  2005cited by this paper
• Botulinum toxin type A for the treatment of the upper limb spasticity after stroke: a meta-analysis.

  2005cited by this paper
• Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke.

  2004influential reference
• Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy.

  2004cited by this paper
• Botulinum toxin type B in upper-limb poststroke spasticity: a double-blind, placebo-controlled trial.

  2004influential reference
• Safety of botulinum toxin type A: a systematic review and meta-analysis

  2004cited by this paper
• Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy.

  2004cited by this paper
• The beneficial antispasticity effect of botulinum toxin type A is maintained after repeated treatment cycles

  2004cited by this paper
• A Double-Blind Randomised Placebo-Controlled Evaluation of Three Doses of Botulinum Toxin Type A (Dysport®) in the Treatment of Spastic Equinovarus Deformity after Stroke

  2003influential reference
• Therapy-based rehabilitation services for stroke patients at home.

  2003cited by this paper
• Anti-spasticity agents for multiple sclerosis.

  2003cited by this paper
• Muscle overactivity and movement dysfunction in the upper motoneuron syndrome.

  2003cited by this paper
• Is the Reduction of Spasticity by Botulinum Toxin A Beneficial for the Recovery of Motor Function of Arm and Hand in Stroke Patients?

  2003cited by this paper
• A summary of spasticity management--a treatment algorithm.

  2002cited by this paper
• Statistical heterogeneity in systematic reviews of clinical trials: a critical appraisal of guidelines and practice

  2002cited by this paper
• Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after a stroke.

  2002cited by this paper
• Botulinum treatment of spasticity: why is it so difficult to show a functional benefit?

  2001cited by this paper
• A randomized, double‐blind, placebo‐controlled study of the efficacy and safety of botulinum toxin type A in upper limb spasticity in patients with stroke

  2001influential reference
• A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Compare the Efficacy and Safety of Three Doses of Botulinum Toxin Type A (Dysport) With Placebo in Upper Limb Spasticity After Stroke

  2000cited by this paper
• A double-blind placebo-controlled study of botulinum toxin in upper limb spasticity after stroke or head injury

  2000cited by this paper
• Evaluating the role of botulinum toxin in the management of focal hypertonia in adults

  2000cited by this paper
• Impact of botulinum toxin type A on disability and carer burden due to arm spasticity after stroke: a randomised double blind placebo controlled trial

  2000cited by this paper
• Mechanisms of action of phenol block and botulinus toxin Type A in relieving spasticity: electrophysiologic investigation and follow-up.

  1999cited by this paper
• Botulinum toxin in motor disorders.

  1999cited by this paper
• A review of the properties and limitations of the Ashworth and modified Ashworth Scales as measures of spasticity

  1999cited by this paper
• Movement Disorders

  1998cited by this paper
• Botulinum toxin type A and short-term electrical stimulation in the treatment of upper limb flexor spasticity after stroke: a randomized, double-blind, placebo-controlled trial

  1998cited by this paper
• Comparison of phenol block and botulinus toxin type A in the treatment of spastic foot after stroke: a randomized, double-blind trial.

  1998cited by this paper
• Comparable studies of the incidence of stroke and its pathological types: results from an international collaboration. International Stroke Incidence Collaboration.

  1997cited by this paper
• Botulinum toxin type A in the treatment of upper extremity spasticity

  1996cited by this paper
• A randomised, double blind, placebo controlled trial of botulinum toxin in the treatment of spastic foot in hemiparetic patients.

  1996cited by this paper
• Botulinum toxin in movement disorders

  1994cited by this paper
• Parkinson's Disease and Movement Disorders

  1990cited by this paper
• Botulinum toxin injections for cervical dystonia

  1990cited by this paper
• Parkinson's Disease and Movement Disorders

  1988cited by this paper
• Interrater reliability of a modified Ashworth scale of muscle spasticity.

  1987cited by this paper
• The control of muscle tone, reflexes, and movement

  1980cited by this paper
• PRELIMINARY TRIAL OF CARISOPRODOL IN MULTIPLE SCLEROSIS.

  1964cited by this paper

• Long-term safety and treatment discontinuation patterns of OnabotulinumtoxinA for post-stroke spasticity: a retrospective study

  2026cites this paper
• Multimodal machine learning to predict response to ultrasound-guided botulinum and vibration therapy in muscle spasticity a clinical and imaging correlation study

  2026cites this paper
• The Impact of Strength Changes on Active Function Following Botulinum Neurotoxin-A (BoNT-A): A Systematic Review

  2025cites this paper
• Botulinum Toxin Combined with Robot-Assisted Therapy for Post-Stroke Spasticity: A Systematic Review

  2025cites this paper
• Patient-Centred and Daily Life-Oriented Botulinum Toxin Treatment for Stroke Survivors with Upper Extremity Spasticity—Effects and Practical Aspects

  2025cites this paper
• Botulinum toxin A combining with robot-assisted bimanual therapy integrating mirror therapy versus botulinum toxin A combining with robot-assisted bimanual therapy in patients with post-stroke spastic fingers: a randomized controlled pilot trial

  2025cites this paper
• The Effects of Whole-Body Vibration on Spasticity in Stroke: A Systematic Review and Meta-Analysis

  2025influential citation
• Gait Reconstruction Strategy Using Botulinum Toxin Therapy Combined with Rehabilitation

  2024cites this paper
• The Effect of Botulinum Neurotoxin-A (BoNT-A) on Muscle Strength in Adult-Onset Neurological Conditions with Focal Muscle Spasticity: A Systematic Review

  2024cites this paper
• Effect of Botulinum Toxin Injections in the Treatment of Spasticity of Different Etiologies: An Umbrella Review

  2024cites this paper
• The Role of Botulinum Toxin Type-A in Spasticity: Research Trends from a Bibliometric Analysis

  2024cites this paper
• Improving Spasticity by Using Botulin Toxin: An Overview Focusing on Combined Approaches

  2024cites this paper
• Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

  2023cites this paper
• Synergic Effect of Robot-Assisted Rehabilitation and Antispasticity Therapy: A Narrative Review

  2023cites this paper
• Current Clinical Trials in Traumatic Brain Injury

  2022cites this paper
• Stroke pathway — An evidence base for commissioning — An evidence review for NHS England and NHS Improvement

  2022cites this paper
• Shear Wave Velocity to Evaluate the Effect of Botulinum Toxin on Post-Stroke Spasticity of the Lower Limb

  2022cites this paper
• Stroke and stroke rehabilitation

  2022cites this paper
• Reliability and diagnostic accuracy of corrected slack angle derived from 2D-SWE in quantitating muscle spasticity of stroke patients

  2022cites this paper
• The Effects of Distributed vs. Condensed Schedule for Robot-Assisted Training with Botulinum Toxin A Injection for Spastic Upper Limbs in Chronic Post-Stroke Subjects

  2021cites this paper
• Prognosis prediction of the effect of botulinum toxin therapy and intensive rehabilitation on the upper arm function in post-stroke patients using hierarchical cluster analysis

  2021cites this paper
• Goal Attainment: A Clinically Meaningful Measure of Success of Botulinum Toxin-A Treatment for Lower Limb Spasticity in Ambulatory Patients

  2021cites this paper
• High Dosage of Botulinum Toxin Type A in Adult Subjects with Spasticity Following Acquired Central Nervous System Damage: Where Are We at?

  2020cites this paper
• Gynecomastia after Botulinum Toxin Injections for Poststroke Spasticity

  2020cites this paper
• Spatiotemporal asymmetry, options of analysis and complex therapy of stance and gait on treadmill in patients with spasticity of the lower limb (after stroke)

  2020cites this paper
• Real-life outcomes in spasticity management: features affecting goal achievement

  2020cites this paper
• Effectiveness of Botulinum Toxin Treatment for Upper Limb Spasticity Poststroke Over Different ICF Domains: a Systematic Review and Meta-Analysis.

  2019cites this paper
• Selection process for botulinum toxin injections in patients with chronic-stage hemiplegic stroke: a qualitative study

  2019cites this paper
• Multidimensional evaluation of changes in limb function following botulinum toxin injection in persons with stroke

  2019cites this paper
• Treatment of Spasticity with Botulinum Toxin: The Stroke Patient’s Perspective

  2019cites this paper
• Post-stroke Spasticity as a Manifestation of Maladaptive Plasticity and its Modulation by Botulinum Toxin Treatment

  2019cites this paper
• Neurobiology and therapeutic applications of neurotoxins targeting transmitter release.

  2019cites this paper
• Neuromuscular electrical stimulation-enhanced rehabilitation is associated with not only motor but also somatosensory cortical plasticity in chronic stroke patients: an interventional study

  2019cites this paper
• Botulinum Toxin Therapy Combined with Rehabilitation for Stroke: A Systematic Review of Effect on Motor Function

  2019cites this paper
• Evidence-based position paper on Physical and Rehabilitation Medicine professional practice for persons with stroke. The European PRM position (UEMS PRM Section).

  2019cites this paper
• Recent developments in clinical trials of botulinum neurotoxins.

  2018cites this paper
• The Effect of Repeated Botulinum Toxin A Therapy Combined with Intensive Rehabilitation on Lower Limb Spasticity in Post-Stroke Patients

  2018cites this paper
• Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on lower limb spasticity classified by spastic muscle echo intensity in post-stroke patients

  2018cites this paper
• A systematic review: efficacy of botulinum toxin in walking and quality of life in post-stroke lower limb spasticity

  2018cites this paper
• Botulinum toxin A is effective to treat tension-type headache caused by hemifacial spasm.

  2017cites this paper
• 뇌졸중 재활치료를 위한 한국형 표준 진료 지침 2016

  2017cites this paper
• Strain sonoelastographic evaluation of biceps muscle intrinsic stiffness after botulinum toxin-A injection

  2017cites this paper
• Efficacy and safety of botulinum toxin type A for upper limb spasticity after stroke or traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis.

  2017cites this paper
• Botulinum toxin use in rehabilitation clinics: a survey to highlight differences and similarities

  2017cites this paper
• Botulinum toxin after stroke: A functional point of view.

  2017cites this paper
• Effect of electrical stimulation as an adjunct to botulinum toxin type A in the treatment of adult spasticity: a systematic review

  2017cites this paper
• Effects of botulinum toxin A therapy and multidisciplinary rehabilitation on upper and lower limb spasticity in post-stroke patients

  2017cites this paper
• OnabotulinumtoxinA Injection for Poststroke Upper‐Limb Spasticity: Guidance for Early Injectors From a Delphi Panel Process

  2017cites this paper
• Advancing the assessment of spasticity in the upper limb post stroke

  2017cites this paper
• Rehabilitation management of post-stroke spasticity

  2017influential citation
• Parkinsonism and Related Disorders

  2016cites this paper
• Frequency and characteristics of goal attainment following BoNT-A injection for management of spasticity

  2016cites this paper
• Faster Reaching in Chronic Spastic Stroke Patients Comes at the Expense of Arm-Trunk Coordination

  2016cites this paper
• Botulinum toxin as early intervention for spasticity after stroke or non-progressive brain lesion: A meta-analysis.

  2016cites this paper
• A systematic review protocol to evaluate the psychometric properties of measures of function within adult neuro-rehabilitation

  2015cites this paper
• Impact of soft splints on upper limb spasticity in chronic patients with disorders of consciousness: A randomized, single-blind, controlled trial

  2015cites this paper
• Factors Influencing Goal Attainment in Patients with Post-Stroke Upper Limb Spasticity Following Treatment with Botulinum Toxin A in Real-Life Clinical Practice: Sub-Analyses from the Upper Limb International Spasticity (ULIS)-II Study

  2015cites this paper
• Chemodenervation for treatment of limb spasticity following spinal cord injury: a systematic review

  2015cites this paper
• Effects of botulinum neurotoxin on spatio-temporal gait parameters of patients with chronic stroke: a prospective open-label study.

  2015cites this paper
• Local Muscle Injection of Botulinum Toxin Type A Synergistically Improves the Beneficial Effects of Repetitive Transcranial Magnetic Stimulation and Intensive Occupational Therapy in Post-Stroke Patients with Spastic Upper Limb Hemiparesis

  2014cites this paper
• Clinical Use of Botulinum Neurotoxin: Neuromuscular Disorders

  2014cites this paper
• Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program.

  2014cites this paper
• Clinical Practice Guideline for Stroke Rehabilitation in Korea 2012

  2014cites this paper
• Supplementary prescribing for spasticity management

  2014cites this paper
• Mittel zur Behandlung der multiplen Sklerose

  2014cites this paper
• Meaningful improvement in walking performance after Botulinum Neurotoxin A (BoNT-A) in chronic spastic patients

  2014cites this paper
• [Post-stroke spasticity of the lower limb: a comprehensive rehabilitation of patients with the use of botulinum toxin (onabotulinumtoxin A)].

  2014cites this paper
• Contractures and Hypertonia of the Arm After Stroke

  2014cites this paper
• Effets de la majoration du déficit moteur du quadriceps, induite expérimentalement, sur la locomotion des patients hémiparétiques

  2014cites this paper
• Controlled Nerve Ablation With Direct Current: Parameters and Mechanisms

  2014cites this paper
• Botulinum neurotoxins as therapeutics

  2014cites this paper
• Interventions for improving upper limb function after stroke.

  2014cites this paper
• Satisfaction with botulinum toxin treatment in post-stroke spasticity: results from two cross-sectional surveys (patients and physicians)

  2014cites this paper
• Outcomes of ambulatory rehabilitation programmes following botulinum toxin for spasticity in adults with stroke.

  2014cites this paper
• Clinical Applications of Botulinum Neurotoxin

  2014cites this paper
• Management of spasticity from spinal cord dysfunction.

  2013cites this paper
• Long-term effects of injection of botulinum toxin type A combined with home-based functional training for post-stroke patients with spastic upper limb hemiparesis

  2013cites this paper
• Treatment with botulinum toxin improves upper-extremity function post stroke: a systematic review and meta-analysis.

  2013cites this paper
• Multidisciplinary rehabilitation following botulinum toxin and other focal intramuscular treatment for post-stroke spasticity.

  2013cites this paper
• Hsp104 Suppresses Polyglutamine-Induced Degeneration Post Onset in a Drosophila MJD/SCA3 Model

  2013cites this paper
• Overview of botulinum toxin as a treatment for spasticity in stroke patients

  2013cites this paper
• Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program Efeitos da toxina botulínica tipo A no pé espástico em pacientes pós-acidente vascular encefálico inseridos em programa de reabilitação

  2013cites this paper
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  2013cites this paper
• Abo‐, Inco‐, Ona‐, and Rima‐Botulinum Toxins in Clinical Therapy: A Primer

  2013cites this paper
• Developing the yeast disaggregase Hsp104 as a treatment for polyglutamine disease in Drosophila

  2013cites this paper
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  2013cites this paper
• Casting for upper limb hypertonia: A retrospective study to determine the factors associated with intervention decisions

  2012cites this paper
• Assessment of functional improvement in the hemiparetic arm following focal rehabilitation intervention

  2012cites this paper
• Stroke and Stroke Rehabilitation

  2012cites this paper
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  2012cites this paper
• Dystonia - The Many Facets

  2012cites this paper
• [Current trends in the use of botulinum treatment(dysport)in post-stroke spasticity].

  2012cites this paper
• The use of botulinum toxin type A in the management of adult-onset focal spasticity: a survey of Australian allied health professionals.

  2012cites this paper
• Botulinum Toxin Injection for Hypertonicity of the Upper Extremity Within 12 Weeks After Stroke

  2012cites this paper
• The Effects of Onabotulinum Toxin A Injection into Rectus Femoris Muscle in Hemiplegic Stroke Patients with Stiff-Knee Gait: A Placebo-Controlled, Nonrandomized Trial

  2012cites this paper
• Dystonia, Spasticity and Botulinum Toxin Therapy: Rationale, Evidences and Clinical Context

  2012cites this paper
• Medical Applications of Clostridia and Clostridial Toxins

  2012cites this paper
• The Underutilization of Intrathecal Baclofen in Poststroke Spasticity

  2011cites this paper
• Dose response with onabotulinumtoxinA for post‐stroke spasticity: A pooled data analysis

  2011cites this paper
• Efficacy and safety of treatment with incobotulinum toxin A (botulinum neurotoxin type A free from complexing proteins; NT 201) in post-stroke upper limb spasticity.

  2011cites this paper