Studies on the transfer of human delayed-type hypersensitivity. I. Partial purification and characterization of two active components.

Two fractions from tuberculin hypersensitive human white blood cells have been found capable of transferring tuberculin delayed hypersensitivity. One of these (C′-5) is a polynucleotide containing adenine, guanine and cytosine, but no uracil. The second transfer factor is contained in a larger molecular weight (A′) fraction found to have γG-globulin and other globulin and probably α1 lipoprotein as well as ribose indicating RNA. A fraction containing macroglobulin was unable to transfer delayed hypersensitivity.

• Publication year

  1966

• Venue

  Journal of Immunology

• Publication date

  1966-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.97.3.407PMID 4162712
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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