Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Thrombosis and Haemostasis

• Publication date

  2014-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/jth.12524PMID 24517219
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper