Why the radiation-attenuated cercarial immunization studies failed to guide the road for an effective schistosomiasis vaccine: A review

Graphical abstract Schistosomula- and adult worms-derived antigens induce predominant Th1 immune responses. The radiation-attenuated cercariae vaccine efficacy is dependent on induction of Th1 and Th2 immune responses. Accordingly, schistosomula- and adult worms-derived antigens used for effective vaccination must be combined with Th2 immune responses-inducing cytokines or molecules as adjuvant.

• Publication year

  2014

• Venue

  Journal of Advanced Research

• Publication date

  2014-10-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.jare.2014.10.002PMID 26257924PMCID 4522536
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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