Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Clinical Investigation

• Publication date

  2001-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI13903PMID 11544267PMCID PMC209390
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Scavenger receptors in innate immunity.

  2002influential reference
• LRP: a multifunctional scavenger and signaling receptor.

  2001cited by this paper
• Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences.

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• Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems.

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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Macrophage scavenger receptor class A: A multifunctional receptor in atherosclerosis.

  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Functional Changes in Scavenger Receptor Binding Conformation Are Induced by Charge Mutants Spanning the Entire Collagen Domain*

  1998cited by this paper
• Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice.

  1998cited by this paper
• Recognizing death: the phagocytosis of apoptotic cells.

  1998cited by this paper
• Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands.

  1998cited by this paper
• The Macrophage Scavenger Receptor Type A Is Expressed by Activated Macrophages and Protects the Host Against Lethal Endotoxic Shock

  1997cited by this paper
• Growth retardation of Mato's fluorescent granular perithelial (FGP) cells in scavenger receptor knockout (SRKO) mice

  1997cited by this paper
• A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

  1997influential reference
• Scavenger receptors in atherosclerosis

  1997cited by this paper
• Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene.

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  1996cited by this paper
• Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• The SRCR superfamily: a family reminiscent of the Ig superfamily.

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors.

  1993influential reference
• Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor

  1993cited by this paper
• Recognition and plasma clearance of endotoxin by scavenger receptors

  1991cited by this paper
• Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

  1990cited by this paper
• An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

  1990cited by this paper

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