Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delivery, and as an immunoadjuvant for vaccines. The present review highlights the recent applications of chitosan and chitosan derivatives in cancer therapy.

• Publication year

  2017

• Venue

  Marine Drugs

• Publication date

  2017-03-27

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.3390/md15040096PMID 28346381PMCID 5408242
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery.

  2018cited by this paper
• Zinc-Modified Nanotransporter of Doxorubicin for Targeted Prostate Cancer Delivery

  2017cited by this paper
• Stimuli-responsive chitosan-based nanocarriers for cancer therapy

  2017cited by this paper
• Enhanced apoptotic and anticancer potential of paclitaxel loaded biodegradable nanoparticles based on chitosan.

  2017cited by this paper
• The impact of the codelivery of drug-siRNA by trimethyl chitosan nanoparticles on the efficacy of chemotherapy for metastatic breast cancer cell line (MDA-MB-231)

  2017cited by this paper
• Chitosan-Based Intranasal Vaccine against Escherichia coli O157:H7

  2016cited by this paper
• DNA/chitosan electrostatic complex.

  2016cited by this paper
• Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles for Enhanced Anticancer Efficacy in Cervical Cancer

  2016cited by this paper
• The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.

  2016influential reference
• Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses

  2016cited by this paper
• Chitosan Nanoparticles for SiRNA Delivery In Vitro.

  2016cited by this paper
• Transferrin functionalized chitosan-PEG nanoparticles for targeted delivery of paclitaxel to cancer cells.

  2016cited by this paper
• Chitosan-based nanoparticles for survivin targeted siRNA delivery in breast tumor therapy and preventing its metastasis

  2016cited by this paper
• Fabrication, characterization and cytotoxicity studies of ionically cross-linked docetaxel loaded chitosan nanoparticles.

  2016cited by this paper
• Modified-chitosan nanoparticles: Novel drug delivery systems improve oral bioavailability of doxorubicin.

  2016cited by this paper
• Construction of METHFR shRNA/5-fluorouracil co-loaded folate-targeted chitosan polymeric nanoparticles and its anti-carcinoma effect on gastric cells growth

  2016cited by this paper
• Low molecular weight chitosan–protamine conjugate for siRNA delivery with enhanced stability and transfection efficiency

  2016cited by this paper
• Chitosan-Decorated Doxorubicin-Encapsulated Nanoparticle Targets and Eliminates Tumor Reinitiating Cancer Stem-like Cells.

  2015cited by this paper
• Chitosan: A Promising Biopolymer in Drug Delivery Applications

  2015cited by this paper
• Enhanced chitosan-DNA interaction by 2-acrylamido-2-methylpropane coupling for an efficient transfection in cancer cells.

  2015cited by this paper
• Enhanced Antiproliferative Effect of Carboplatin in Cervical Cancer Cells Utilizing Folate-Grafted Polymeric Nanoparticles

  2015cited by this paper
• Cancer-targeted MDR-1 siRNA delivery using self-cross-linked glycol chitosan nanoparticles to overcome drug resistance.

  2015cited by this paper
• Development of hybrid-type modified chitosan derivative nanoparticles for the intracellular delivery of midkine-siRNA in hepatocellular carcinoma cells.

  2015cited by this paper
• Application of Chitosan-Based Nanocarriers in Tumor-Targeted Drug Delivery

  2015cited by this paper
• Chitosan-based vaccine adjuvants: incomplete characterization complicates preclinical and clinical evaluation

  2015cited by this paper
• Preparation and Testing of Quaternized Chitosan Nanoparticles as Gene Delivery Vehicles

  2015cited by this paper
• Exploring Advantages/Disadvantages and Improvements in Overcoming Gene Delivery Barriers of Amino Acid Modified Trimethylated Chitosan

  2015cited by this paper
• Paclitaxel-loaded N-octyl-O-sulfate chitosan micelles for superior cancer therapeutic efficacy and overcoming drug resistance.

  2014cited by this paper
• RVG-peptide-linked trimethylated chitosan for delivery of siRNA to the brain.

  2014cited by this paper
• Non-viral vectors for gene-based therapy

  2014cited by this paper
• Low Molecular Weight Chitosan (LMWC)-based Polyplexes for pDNA Delivery: From Bench to Bedside

  2014cited by this paper
• Chitosan coated polylactic acid nanoparticle-mediated combinatorial delivery of cisplatin and siRNA/Plasmid DNA chemosensitizes cisplatin-resistant human ovarian cancer cells.

  2014cited by this paper
• Chitosan-DNA complexes: charge inversion and DNA condensation.

  2014cited by this paper
• A prodrug strategy based on chitosan for efficient intracellular anticancer drug delivery

  2014cited by this paper
• New chitosan nanospheres for the delivery of 5-fluorouracil: preparation, characterization and in vitro studies.

  2014cited by this paper
• Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression.

  2013cited by this paper
• Alginic Acid-Coated Chitosan Nanoparticles Loaded with Legumain DNA Vaccine: Effect against Breast Cancer in Mice

  2013cited by this paper
• Extracellular and Intracellular Barriers to Non-Viral Gene Transfer

  2013cited by this paper
• Hyaluronidase enzyme core-5-fluorouracil-loaded chitosan-PEG-gelatin polymer nanocomposites as targeted and controlled drug delivery vehicles.

  2013cited by this paper
• Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances.

  2013cited by this paper
• Novel biotinylated chitosan-graft-polyethyleneimine copolymer as a targeted non-viral vector for anti-EGF receptor siRNA delivery in cancer cells.

  2013cited by this paper
• Chitosan-based biomaterials for tissue engineering

  2013cited by this paper
• Low molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization studies

  2012influential reference
• Enhanced siRNA delivery and silencing gold-chitosan nanosystem with surface charge-reversal polymer assembly and good biocompatibility.

  2012cited by this paper
• Viral and nonviral delivery systems for gene delivery

  2012cited by this paper
• Preparation and Efficacy of a Live Newcastle Disease Virus Vaccine Encapsulated in Chitosan Nanoparticles

  2012cited by this paper
• Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery

  2012cited by this paper
• Dendronized chitosan derivative as a biocompatible gene delivery carrier.

  2011cited by this paper
• Chitosan Nanoparticles Act as an Adjuvant to Promote both Th1 and Th2 Immune Responses Induced by Ovalbumin in Mice

  2011influential reference
• Carbohydrate-based immune adjuvants

  2011cited by this paper
• In vivo efficacy of a chitosan/IL-12 adjuvant system for protein-based vaccines.

  2011cited by this paper
• Targeted delivery of doxorubicin-utilizing chitosan nanoparticles surface-functionalized with anti-Her2 trastuzumab

  2011cited by this paper
• Polymers in Small-Interfering RNA Delivery

  2011cited by this paper
• Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.

  2011cited by this paper
• Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis*

  2011cited by this paper
• Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms

  2010cited by this paper
• Enhanced Gene Delivery Mediated by Low Molecular Weight Chitosan/DNA Complexes: Effect of pH and Serum

  2010cited by this paper
• Biomedical applications of chitin and chitosan based nanomaterials—A short review

  2010cited by this paper
• Intratumoral Immunotherapy of Established Solid Tumors With Chitosan/IL-12

  2010influential reference
• Delivery of siRNA Therapeutics: Barriers and Carriers

  2010cited by this paper
• Nucleic Acid Delivery with Chitosan Hydroxybenzotriazole

  2010cited by this paper
• The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation.

  2010cited by this paper
• Chitosan-based formulations for delivery of DNA and siRNA.

  2010influential reference
• Doxorubicin-incorporated nanoparticles composed of poly(ethylene glycol)-grafted carboxymethyl chitosan and antitumor activity against glioma cells in vitro.

  2010cited by this paper
• Anti-tumor activity of paclitaxel-loaded chitosan nanoparticles: An in vitro study

  2009cited by this paper
• Receptor mediated gene delivery by folate conjugated N-trimethyl chitosan in vitro.

  2009cited by this paper
• Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12.

  2009cited by this paper
• Polymeric nanoparticles of cholesterol‐modified glycol chitosan for doxorubicin delivery: preparation and in‐vitro and in‐vivo characterization

  2009cited by this paper
• Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery.

  2009cited by this paper
• Chitosan-based systems for the delivery of vaccine antigens

  2009cited by this paper
• Knocking down barriers: advances in siRNA delivery

  2009cited by this paper
• A Novel Nanoparticle Formulation for Sustained Paclitaxel Delivery

  2008cited by this paper
• Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro.

  2008cited by this paper
• Polymeric nanocarriers for siRNA delivery: Challenges and future prospects

  2008cited by this paper
• Marine Products for Healthcare: Functional and Bioactive Nutraceutical Compounds from the Ocean

  2008cited by this paper
• Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice.

  2008cited by this paper
• Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination.

  2007influential reference
• Chitosan solution enhances the immunoadjuvant properties of GM-CSF.

  2007influential reference
• A novel PEGylation of chitosan nanoparticles for gene delivery

  2007cited by this paper
• Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery.

  2007influential reference
• The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

  2007cited by this paper
• High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation.

  2006cited by this paper
• Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel.

  2006cited by this paper
• Gene therapy for cancer treatment: past, present and future.

  2006cited by this paper
• Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes.

  2005cited by this paper
• Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation.

  2005influential reference
• Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

  2004cited by this paper
• Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

  2001cited by this paper
• Water-Soluble and Low Molecular Weight Chitosan-Based Plasmid DNA Delivery

  2001cited by this paper
• Mechanism of cell transfection with plasmid/chitosan complexes.

  2001cited by this paper
• In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency.

  2001cited by this paper
• Chitosans as nasal absorption enhancers of peptides: comparison between free amine chitosans and soluble salts.

  2000cited by this paper
• Immunological aspects of chitin and chitin derivatives administered to animals.

  1999cited by this paper
• Gene Delivery by Quaternary Chitosan with Antennary Galactose Residues

  1999cited by this paper
• Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability

  1998cited by this paper
• Development of Doxorubicin-Core Shell Chitosan Nanoparticles to Treat Cancer

  year unknowninfluential reference
• Iranian Journal of Basic Medical Sciences Gene Therapy Based on Interleukin-12 Loaded Chitosan Nanoparticles in a Mouse Model of Fibrosarcoma

  year unknowncited by this paper

• Innovative PEGylated chitosan nanocarriers for co-delivery of doxorubicin and CpG in breast cancer therapy: Preparation, characterization, and immunotherapeutic potential

  2025cites this paper
• Advanced Technologies for Large Scale Supply of Marine Drugs

  2025cites this paper
• Advances in the systemic administration of nanotechnology-mediated drug delivery systems in melanoma treatment: a systematic review

  2025cites this paper
• Chitosan Nanoparticles: Approaches to Preparation, Key Properties, Drug Delivery Systems, and Developments in Therapeutic Efficacy

  2025cites this paper
• Modulation of voltage-gated sodium channels by a nanoencapsulated α-toxin from Aah scorpion venom in an experimental lung cancer model

  2025cites this paper
• Advances in chitosan-based nanofiber for breast cancer treatment: A review.

  2025cites this paper
• Natural polysaccharides in colloidal drug delivery systems for brain glioma therapy: Mechanisms and advancements.

  2025cites this paper
• Natural bioactive compounds loaded chitosan nanocarriers: a promising strategy for breast cancer therapy

  2025cites this paper
• Preclinical, clinical, and commercialization of chitosan in the biomedical space.

  2025cites this paper
• Marine-Derived Molecular Glue Degraders: A New Frontier in Targeted Protein Degradation for Treatment of Multi-Factorial Diseases.

  2025cites this paper
• Integrating 3D Bioprinting with Organoid Technology-Based Breast Cancer Models for Drug Evaluation

  2025cites this paper
• A dual-functional cobalt ferrite nanocomplex for targeted cisplatin prodrug delivery and MALAT1 gene silencing in gastric cancer cells

  2025cites this paper
• Melatonin-loaded lecithin and chitosan nanoparticles are cytotoxic to 4 T1 breast cancer cells and safe in a BALB/c mouse model.

  2025cites this paper
• Chitosan-based Nano/Biomaterials in Bone Tissue Engineering and Regenerative Medicine: Recent Progress and Advances.

  2024cites this paper
• Chemically modified chitosan as a functional biomaterial for drug delivery system.

  2024cites this paper
• Recent progress of functional nano-chitosan in pharmaceutical and biomedical applications: An updated review.

  2024cites this paper
• Study on the inhibition of non-small cell lung cancer mediated by chitosan-based gene carrier delivering STAT3-shRNA.

  2024cites this paper
• Carbohydrate polymer-driven nanoparticle synthesis and functionalization in the brain tumor therapy: A review.

  2024cites this paper
• Chitosan-based hydrogels in cancer therapy: Drug and gene delivery, stimuli-responsive carriers, phototherapy and immunotherapy.

  2024cites this paper
• Iontophoresis-Enhanced Buccal Delivery of Cisplatin-Encapsulated Chitosan Nanoparticles for Treating Oral Cancer in a Mouse Model

  2024cites this paper
• A review of chitosan polysaccharides: Neuropharmacological implications and tissue regeneration.

  2024cites this paper
• Fabrication and characterization of unique sustain modified chitosan nanoparticles for biomedical applications

  2024cites this paper
• Glycan-based scaffolds and nanoparticles as drug delivery system in cancer therapy

  2024cites this paper
• Trimethyl chitosan–cysteine-based nanoparticles as an effective delivery system for portulacerebroside A in the management of hepatocellular carcinoma cells in vitro and in vivo

  2024cites this paper
• Application of Chitosan in Industry and Medicine: A Mini-Review

  2024cites this paper
• Chitosan in cancer therapy: a dual role as a therapeutic agent and drug delivery system

  2024cites this paper
• Biomedical potential of hydrogels: a multifaceted approach to innovative medication delivery

  2024cites this paper
• Structure and functionality of cinnamaldehyde/chitosan/gum Arabic complex particles

  2023cites this paper
• Facile engineering of chitosan-coated aminopterin loaded zeolitic imidazolate framework: promising drug delivery system for breast cancer

  2023cites this paper
• Polydopamine-containing nano-systems for cancer multi-mode diagnoses and therapies: A review.

  2023cites this paper
• Amelioration of Cancer Employing Chitosan, Its Derivatives, and Chitosan-Based Nanoparticles: Recent Updates

  2023cites this paper
• Nanocomposite Hydrogels-A Promising Approach towards Enhanced Bioavailability and Controlled Drug Delivery.

  2023cites this paper
• Determination of Common microRNA Biomarker Candidates in Stage IV Melanoma Patients and a Human Melanoma Cell Line: A Potential Anti-Melanoma Agent Screening Model

  2023cites this paper
• Theoretical and Experimental Aspects of Sodium Diclofenac Salt Release from Chitosan-Based Hydrogels and Possible Applications

  2023cites this paper
• Multi-functional chitosan-based nanoparticles for drug delivery: Recent advanced insight into cancer therapy.

  2023cites this paper
• A review of chitosan in gene therapy: Developments and challenges.

  2023cites this paper
• Electrosprayed Chitosan Nanoparticles for Drug Carriers in Cancer Treatment - A Mini Review

  2023influential citation
• Characterisation and functionalisation of chitosan nanoparticles as carriers for double-stranded RNA (dsRNA) molecules towards sustainable crop protection

  2023cites this paper
• Polysaccharide-Drug Conjugates: A Tool for Enhanced Cancer Therapy

  2022cites this paper
• Chitosan: A review of molecular structure, bioactivities and interactions with the human body and micro-organisms.

  2022cites this paper
• Tumor targeting strategies by chitosan-based nanocarriers

  2022cites this paper
• GASTRO RETENTIVE DRUG DELIVERY SYSTEM

  2022cites this paper
• Rationally-designed chitosan-based polymeric nanomaterials according to intrinsic characteristics for cancer therapy and theranostics: a review.

  2022cites this paper
• Chitosan-based drug delivery systems in cancer therapeutics

  2022cites this paper
• A review on plant polysaccharide based on drug delivery system for construction and application, with emphasis on traditional Chinese medicine polysaccharide.

  2022cites this paper
• Current advances in the application of nanomedicine in bladder cancer.

  2022cites this paper
• The effects of dendritic cell-based vaccines in the tumor microenvironment: Impact on myeloid-derived suppressor cells

  2022cites this paper
• Chitosan/Gamma-Alumina/Fe3O4@5-FU Nanostructures as Promising Nanocarriers: Physiochemical Characterization and Toxicity Activity

  2022cites this paper
• Chitosan-stabilized platinum nanoparticles induce apoptotic cell death in breast cancer cells

  2022influential citation
• Biodegradable Polymer Matrix Composites Containing Graphene-Related Materials for Antibacterial Applications: A Critical Review.

  2022cites this paper
• Atmospheric Plasma‐Assisted Deposition and Patterning of Natural Polymers

  2022cites this paper
• Recent Advances in Chitosan and its Derivatives in Cancer Treatment

  2022cites this paper
• Current Advances in 3D Bioprinting for Cancer Modeling and Personalized Medicine

  2022cites this paper
• A Short Review on Recent Applications of Chitosan Biopolymer in Gene and Drug Delivery

  2022cites this paper
• Bioadhesive chitosan nanoparticles: Dual targeting and pharmacokinetic aspects for advanced lung cancer treatment.

  2021cites this paper
• Drug delivery systems based on CD44-targeted glycosaminoglycans for cancer therapy.

  2021cites this paper
• Co-delivery chitosan nanoparticles of 5-aminolevulinic acid and shGBAS for improving photodynamic therapy efficacy in oral squamous cell carcinomas.

  2021cites this paper
• Folic Acid-Doxorubicin-Double-Functionalized-Lipid-Core Nanocapsules: Synthesis, Chemical Structure Elucidation, and Cytotoxicity Evaluation on Ovarian (OVCAR-3) and Bladder (T24) Cancer Cell Lines

  2021cites this paper
• Recent Advances in Nanotechnology with Nano-Phytochemicals: Molecular Mechanisms and Clinical Implications in Cancer Progression

  2021cites this paper
• Prospects of Delivering Natural Compounds by Polymer-Drug Conjugates in Cancer Therapeutics.

  2021cites this paper
• Chitosan modified by organo-functionalities as an efficient nanoplatform for anti-cancer drug delivery process

  2021cites this paper
• Chitin, chitosan, and their derivatives

  2021cites this paper
• Plausible role of chitosan in drug and gene delivery against resistant breast cancer cells.

  2021cites this paper
• Marine Polysaccharides as a Versatile Biomass for the Construction of Nano Drug Delivery Systems

  2021cites this paper
• Insight into chitosan derived nanotherapeutics for anticancer drug delivery and imaging

  2021cites this paper
• Marine polysaccharides: green and recyclable resources as wound dressings

  2021cites this paper
• Chitosan-based bionanocomposites for cancer therapy

  2021cites this paper
• Anti-tumour drugs of marine origin currently at various stages of clinical trials (review)

  2021cites this paper
• Cellulose Nanocrystals/Chitosan-Based Nanosystems: Synthesis, Characterization, and Cellular Uptake on Breast Cancer Cells

  2021cites this paper
• Electrochemical characterization of electrophoretically deposited hydroxyapatite/chitosan/graphene oxide composite coating on Mg substrate

  2021cites this paper
• Controlled Drug Delivery Systems: Current Status and Future Directions

  2021cites this paper
• Stimuli-responsive biopolymeric systems for drug delivery to cancer cells

  2021cites this paper
• Recent Progress in Biomedical Applications of Chitosan Derivatives as Gene Carrier

  2021cites this paper
• A Poly-Chitosan and Cis-Platinum Conjugated Composite Nanoparticle System for Liver Cancer Therapy.

  2021cites this paper
• Using Chitosan or Chitosan Derivatives in Cancer Therapy

  2021cites this paper
• Chitin – A Structural Polysaccharide for Health and Environmental Alimentation

  2021cites this paper
• Chitosan-based inks for 3D printing and bioprinting

  2021cites this paper
• Therapeutic nanoparticles in the brain: a review of types, physicochemical properties and challenges.

  2021cites this paper
• TARGETED DRUG DELIVERY SYSTEM; NANOPARTICLE BASED COMBINATION OF CHITOSAN AND ALGINATE FOR CANCER THERAPY: A REVIEW

  2021cites this paper
• CHITOSAN NANOPARTICLES AND ITS IMPACT ON GROWTH, YIELD, SOME BIOCHEMICAL AND MOLECULAR MARKERS IN SILYBIUM MARIANUM

  2021cites this paper
• Nano-drug delivery system for the treatment of acute myelogenous leukemia.

  2021cites this paper
• Insights into Novel Antimicrobial Based on Chitosan Nanoparticles: From a Computational and Experimental Perspective

  2020cites this paper
• Marine-derived drugs: Recent advances in cancer therapy and immune signaling.

  2020cites this paper
• Chitosan applications in studying and managing osteosarcoma.

  2020cites this paper
• Recent Advances in Particulate Adjuvants for Cancer Vaccination

  2020cites this paper
• Marine-derived biomaterials for cancer treatment

  2020cites this paper
• Chitin and chitosan—important structural components in Trichoderma cell wall remodeling

  2020cites this paper
• Chitosan microparticles as entrapment system for trans-cinnamaldehyde: Synthesis, drug loading, and in vitro cytotoxicity evaluation.

  2020cites this paper
• Synthesis of Novel Chitosan-Grafted-Derivatives Nano Cationic Polymers as Antitumor Agents

  2020cites this paper
• Marine‐origin Polysaccharides for Tissue Engineering and Regenerative Medicine

  2020cites this paper
• Alginate-Based Platforms for Cancer-Targeted Drug Delivery

  2020cites this paper
• Effects of chitosan and oligochitosans on the phosphatidylinositol 3-kinase-AKT pathway in cancer therapy.

  2020cites this paper
• Effects of chitosan-loaded hydroxyapatite on osteoblasts and osteosarcoma for chemopreventative applications.

  2020cites this paper
• Role of Pd(II)–chitooligosaccharides–Gboxin analog in oxidative phosphorylation inhibition and energy depletion: Targeting mitochondrial dynamics

  2020cites this paper
• Cytotoxicity influence of new chitosan composite on HEPG-2, HCT-116 and MCF-7 carcinoma cells.

  2020cites this paper
• Eugenol nanocapsules embedded with gelatin-chitosan for chilled pork preservation.

  2020cites this paper
• Doxorubicin loaded on chitosan-protamine nanoparticles triggers apoptosis via downregulating Bcl-2 in breast cancer cells

  2020cites this paper
• PEGylated chitosan / doxorubicin nanoparticles and conjugated with monoclonal antibodies for breast cancer therapy

  2020cites this paper
• Comparative Cytotoxicity and Genotoxicity Assessments of Chitosan Amino Acid Derivative Nanoparticles Toward Human Breast Cancer Cell Lines

  2019cites this paper
• Chitosan is a potential inhibitor of ovarian cancer: Molecular aspects

  2019cites this paper