Glycosyltransferases. Structure, localization, and control of cell type-specific glycosylation.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Journal of Biological Chemistry

• Publication date

  1989-10-25

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 2681181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Glycoproteins: what are the sugar chains for?

  1989cited by this paper
• An alpha-N-acetylgalactosaminylation at the threonine residue of a defined peptide sequence creates the oncofetal peptide epitope in human fibronectin.

  1989cited by this paper
• Glycolipid glycosyltransferases in human embryonal carcinoma cells during retinoic acid induced differentiation.

  1989cited by this paper
• Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase.

  1989cited by this paper
• A cloned human DNA restriction fragment determines expression of a GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in transfected cells. Evidence for isolation and transfer of the human H blood group locus.

  1989cited by this paper
• Studies on the effect of lysosomotropic agents on the release of Gal beta 1-4GlcNAc alpha-2,6-sialytransferase from rat liver slices during the acute-phase response.

  1989cited by this paper
• Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells.

  1989cited by this paper
• Stable expression of blood group H determinants and GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase in mouse cells after transfection with human DNA.

  1989cited by this paper
• Bovine alpha 1----3-galactosyltransferase: isolation and characterization of a cDNA clone. Identification of homologous sequences in human genomic DNA.

  1989cited by this paper
• Conversion of a Golgi apparatus sialyltransferase to a secretory protein by replacement of the NH2-terminal signal anchor with a signal peptide.

  1989cited by this paper
• Cloning of cDNA encoding the membrane-bound form of bovine beta 1,4-galactosyltransferase.

  1989cited by this paper
• Tissue-specific expression of sialyltransferases.

  1989cited by this paper
• Regulation of beta-galactoside alpha 2,6-sialyltransferase gene expression by dexamethasone.

  1989cited by this paper
• MG-160. A novel sialoglycoprotein of the medial cisternae of the Golgi apparatus [published eeratum appears in J Biol Chem 1989 Mar 5;264(7):4264].

  1989cited by this paper
• Regulation of protein export from the endoplasmic reticulum.

  1988cited by this paper
• Evidence that luminal ER proteins are sorted from secreted proteins in a post‐ER compartment.

  1988cited by this paper
• The neural cell adhesion molecule (NCAM) as a regulator of cell-cell interactions.

  1988cited by this paper
• Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells.

  1988cited by this paper
• Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5'-end predict two translational start sites at two in-frame AUGs.

  1988cited by this paper
• Analysis of cellular expression of gangliosides by gene transfection. II: Rat 3Y1 cells transformed with several DNAs containing oncogenes (fes, fps, ras & src) invariably express sialosylparagloboside.

  1988cited by this paper
• Neolacto-series gangliosides induce granulocytic differentiation of human promyelocytic leukemia cell line HL-60.

  1988cited by this paper
• Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.

  1988cited by this paper
• Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions.

  1988cited by this paper
• Ganglioside-mediated modulation of cell growth. Specific effects of GM3 and lyso-GM3 in tyrosine phosphorylation of the epidermal growth factor receptor.

  1988cited by this paper
• Retinoic acid-induced differentiation of the mouse teratocarcinoma cell line F9 is accompanied by an increase in the activity of UDP-galactose: beta-D-galactosyl-alpha 1,3-galactosyltransferase.

  1988cited by this paper
• Cloning and sequencing of a full-length cDNA of mouse N-acetylglucosamine (beta 1-4)galactosyltransferase.

  1988cited by this paper
• Growth control of human foreskin fibroblasts and inhibition of extracellular sialidase activity by 2-deoxy-2,3-dehydro-N-acetylneuraminic acid.

  1988cited by this paper
• Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus

  1988cited by this paper
• Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta 1,4-galactosyltransferase).

  1988cited by this paper
• A pituitary N-acetylgalactosamine transferase that specifically recognizes glycoprotein hormones

  1988cited by this paper
• Analysis of cellular expression of gangliosides by gene transfection. I: GD3 expression in myc-transfected and transformed 3Y1 correlates with anchorage-independent growth activity.

  1988cited by this paper
• Glycobiology.

  1988cited by this paper
• Two distinct classes of carbohydrate-recognition domains in animal lectins.

  1988cited by this paper
• Ganglioside-modulated protein phosphorylation. Partial purification and characterization of a ganglioside-inhibited protein kinase in brain.

  1988cited by this paper
• Site of addition of N-acetyl-galactosamine to the E1 glycoprotein of mouse hepatitis virus-A59

  1988cited by this paper
• Early events in mammalian fertilization.

  1987cited by this paper
• Two integral membrane proteins located in the cis-middle and trans-part of the Golgi system acquire sialylated N-linked carbohydrates and display different turnovers and sensitivity to cAMP-dependent phosphorylation

  1987cited by this paper
• The membrane-binding domain of a rat liver Golgi sialyltransferase.

  1987cited by this paper
• Subcellular organization of glycosylation in mammalian cells.

  1987cited by this paper
• Primary structure of beta-galactoside alpha 2,6-sialyltransferase. Conversion of membrane-bound enzyme to soluble forms by cleavage of the NH2-terminal signal anchor.

  1987cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
• Predefined gene transfer for expression of a glycosphingolipid antigen by transfection with a cosmid genomic library prepared from a cell line in which the specific glycosphingolipid is highly expressed.

  1987cited by this paper
• Trafficking of lysosomal enzymes 1

  1987cited by this paper
• Activation of CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase during the differentiation of HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate.

  1986cited by this paper
• Bovine galactosyltransferase: identification of a clone by direct immunological screening of a cDNA expression library.

  1986cited by this paper
• Purification and characterization of a UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase from Ehrlich ascites tumor cells.

  1986cited by this paper
• Activity and secretion of sialyltransferase in primary monolayer cultures of rat hepatocytes cultured with and without dexamethasone.

  1986cited by this paper
• Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.

  1986cited by this paper
• Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens

  1985cited by this paper
• Biosynthesis of terminal Gal alpha 1----3Gal beta 1----4GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide alpha 1----3-galactosyltransferase from calf thymus.

  1985cited by this paper
• Terminal glycosylation in rat hepatic Golgi fractions: heterogeneous locations for sialic acid and galactose acceptors and their transferases.

  1985cited by this paper
• Multiple mechanisms of protein insertion into and across membranes.

  1985cited by this paper
• Localization of galactosyl- and sialyltransferase by immunofluorescence: evidence for different sites.

  1985cited by this paper
• Assembly of asparagine-linked oligosaccharides.

  1985cited by this paper
• Cytochemical localization of terminal N-acetyl-D-galactosamine residues in cellular compartments of intestinal goblet cells: implications for the topology of O-glycosylation

  1984cited by this paper
• Tumor-associated carbohydrate antigens.

  1984cited by this paper
• Oligosaccharides containing fucose linked alpha(1-3) and alpha(1-4) to N-acetylglucosamine cause decompaction of mouse morulae.

  1984cited by this paper
• A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective

  1984cited by this paper
• Host-dependent variation of asparagine-linked oligosaccharides at individual glycosylation sites of Sindbis virus glycoproteins.

  1983cited by this paper
• GQ1b, a bioactive ganglioside that exhibits novel nerve growth factor (NGF)-like activities in the two neuroblastoma cell lines.

  1983cited by this paper
• Stimulation of sialyltransferase activity of melanoma cells by retinoic acid.

  1983cited by this paper
• Biosynthesis, intracellular transport, and release of the Golgi enzyme galactosyltransferase (lactose synthetase A protein) in HeLa cells.

  1982cited by this paper
• Biology of carbohydrates

  1981cited by this paper
• Glycosyltransferases and their use in assessing oligosaccharide structure and structure-function relationships.

  1981cited by this paper
• Co-purification of the Lewis blood group N-acetylglucosaminide alpha 1 goes to 4 fucosyltransferase and an N-acetylglucosaminide alpha 1 goes to 3 fucosyltransferase from human milk.

  1981cited by this paper
• Butyrate-induced glycolipid biosynthesis in HeLa cells: properties of the induced sialyltransferase.

  1976cited by this paper
• Altered ganglioside biosynthesis in mouse cell cultures following transformation with chemical carcinogens and x-irradiation.

  1975cited by this paper
• Glycosyltransferases in human blood. II. Study of serum galactosyltransferase and N-acetylgalactosaminyltransferase in patients with liver diseases.

  1972cited by this paper

• A novel missense variant c.674T>C (p.Leu225Pro) underlies the Ael phenotype in a Chinese blood donor.

  2026cites this paper
• Glycosyltransferases: glycoengineers in human milk oligosaccharide synthesis and manufacturing

  2025cites this paper
• The role of polysaccharides in immune regulation through gut microbiota: mechanisms and implications

  2025cites this paper
• GalNAc-Transferases in Cancer

  2025influential citation
• Characterization of a novel ABO allele with variant c.575T>C on an A1.01.02 background

  2025cites this paper
• Membrane glycoproteins get another go: the GlycoSwitch.

  2025cites this paper
• Antigens in membranous nephropathy: discovery and clinical implications

  2025cites this paper
• Identification of a novel B allele with a nucleotide change (c.826G>T) responsible for Bel phenotype

  2025cites this paper
• Methods for the synthesis of natural UDP-sugars and synthetic analogues.

  2025cites this paper
• Mechanistic overview of protein-specific polysialylation

  2025cites this paper
• Identification of five novel ABO blood group alleles

  2025cites this paper
• Characterization and application of active human α2,6-sialyltransferases ST6GalNAc V and ST6GalNAc VI recombined in Escherichia coli.

  2024cites this paper
• Proteolytic cleavage of Golgi glycosyltransferases by SPPL3 and other proteases and its implications for cellular glycosylation: (special issue title: New aspects of glycosyltransferases).

  2024cites this paper
• Recent Developments and Application of Mass Spectrometry Imaging in N-Glycosylation Studies: An Overview

  2024cites this paper
• Genetics of glycosylation in mammalian development and disease

  2024cites this paper
• The Nicotiana tabacum UGT89A2 enzyme catalyzes the glycosylation of di- and trihydroxylated benzoic acid derivatives.

  2024cites this paper
• The stem region of group A transferase is crucial for its specificity, and its alteration promotes heterologous Forssman synthase activity

  2023cites this paper
• Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas

  2023cites this paper
• Identification of a novel weak A allele with c.27delC in a Chinese individual

  2023cites this paper
• Identification of copper death-associated molecular clusters and immunological profiles in rheumatoid arthritis

  2023cites this paper
• Increasing Complexity of the N-Glycome During Caenorhabditis Development

  2023cites this paper
• Long-term super-resolution inner mitochondrial membrane imaging with a lipid probe

  2023cites this paper
• New antigens involved in membranous nephropathy beyond phospholipase A2 receptor

  2022cites this paper
• Long-term, super-resolution HIDE imaging of the inner mitochondrial membrane in live cells with a cell-permeant lipid probe

  2022cites this paper
• Sulfation of sialic acid is ubiquitous and essential for vertebrate development

  2022cites this paper
• Haploinsufficiency of EXT1 and Heparan Sulphate Deficiency Associated with Hereditary Multiple Exostoses in a Pakistani Family

  2022cites this paper
• Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story

  2022cites this paper
• Applying transcriptomics to studyglycosylation at the cell type level

  2022cites this paper
• N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion

  2022cites this paper
• Update on New Antigens in the Pathogenesis of Membranous Nephropathy

  2022cites this paper
• ST3GAL2 knock-down decreases tumoral character of colorectal cancer cells in vitro and in vivo.

  2022cites this paper
• Polypeptide N-acetylgalactosamine transferase 3: a post-translational writer on human health

  2022cites this paper
• Polypeptide N-acetylgalactosaminyltransferase 18 Retains in Endoplasmic Reticulum Depending on its Luminal Regions Interacting with ER resident UGGT1, PLOD3 and LPCAT1.

  2021cites this paper
• The role of altered glycosylation in human nucleus pulposus cells in inflammation and degeneration.

  2021cites this paper
• In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes.

  2021cites this paper
• A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and catalytic activity is essential in parasitic Leishmania major

  2021cites this paper
• A quantitative study of the Golgi retention of glycosyltransferases

  2021cites this paper
• Glycan Recognition in Human Norovirus Infections

  2021cites this paper
• A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and activity are essential in parasitic Leishmania

  2021cites this paper
• Course monitoring of membranous nephropathy: Both autoantibodies and podocytes require multidimensional attention.

  2021cites this paper
• A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and catalytic activity is essential in the parasitic protozoan Leishmania

  2021cites this paper
• Immunopathological analysis of the expression of glomerular exostosin 1 and exostosin 2 in Japanese patients with lupus nephritis

  2021cites this paper
• Signaling Functions of Intramembrane Aspartyl-Proteases

  2020cites this paper
• New 'Antigens' in Membranous Nephropathy.

  2020cites this paper
• Status Quo of Glycosylation in Cancer: What Is, What Is Not and What Is to Be

  2020cites this paper
• Insights into Bioinformatic Applications for Glycosylation: Instigating an Awakening towards Applying Glycoinformatic Resources for Cancer Diagnosis and Therapy

  2020cites this paper
• Xenotransplantation and Glycomedicine

  2020cites this paper
• Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases

  2020cites this paper
• α- and β-1,3-Glucan Synthesis and Remodeling.

  2020cites this paper
• Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice.

  2020cites this paper
• Two novel mutations p. L319V and p. L91P in ABO glycosyltransferases lead to Ael and Bel phenotypes.

  2020cites this paper
• Global view of human protein glycosylation pathways and functions

  2020cites this paper
• A 24‐base pair deletion in the ABO gene causes a hereditary splice site defect: a novel mechanism underlying ABO blood group O

  2020cites this paper
• Recent Progress in Chemo-Enzymatic Methods for the Synthesis of N-Glycans

  2020cites this paper
• Enzymatic approaches to new protein conjugates

  2020cites this paper
• Physiological functions of SPP/SPPL intramembrane proteases

  2020cites this paper
• A Random Forest Sub-Golgi Protein Classifier Optimized via Dipeptide and Amino Acid Composition Features

  2019cites this paper
• Glycosylation and glycan interactions can serve as extracellular machinery facilitating clathrin‐independent endocytosis

  2019cites this paper
• Structure and Function of a Chlorella Virus EncodedGlycosyltransferase

  2019cites this paper
• Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)

  2019cites this paper
• Computational analysis of the structure, glycosylation and CMP binding of human ST3GAL sialyltransferases.

  2019cites this paper
• The neutral N-linked glycans of the Basidiomycetous yeasts Pseudozyma antarctica and Malassezia furfur (Subphylum Ustilaginomycotina).

  2019cites this paper
• A tale of short tails, through thick and thin: investigating the sorting mechanisms of Golgi enzymes

  2019cites this paper
• Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae

  2019cites this paper
• A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-Glycosylation.

  2019cites this paper
• Etude de l'implication des acides sialiques dans la régulation de la fusion myoblastique

  2019cites this paper
• Translation of genome to glycome: role of the Golgi apparatus

  2019cites this paper
• Multiple miscarriages in two sisters of Thai origin with the rare Pk phenotype caused by a novel nonsense mutation at the B3GALNT1 locus

  2018cites this paper
• Implementation of a Novel Fucosyltransferase Inhibition Assay on a Digital Microfluidics Device

  2018cites this paper
• Glycosylation of Recombinant Anticancer Therapeutics in Different Expression Systems with Emerging Technologies.

  2018cites this paper
• Synthesis and Preliminary Evaluation of Biological Activity of Glycoconjugates Analogues of Acyclic Uridine Derivatives

  2018cites this paper
• Expression system for structural and functional studies of human glycosylation enzymes.

  2018cites this paper
• IgG and leukocytes: Targets of immunomodulatory α2,6 sialic acids.

  2018cites this paper
• Elucidating the roles of Alzheimer disease-associated proteases and the signal-peptide peptidase-like 3 (SPPL3) in the shedding of glycosyltransferases

  2018cites this paper
• A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation

  2018cites this paper
• Comparative Binding Analysis ofN-Acetylneuraminic Acid in Bovine Serum Albumin and Human α-1 Acid Glycoprotein

  2018cites this paper
• Transglutaminase and Sialyltransferase Enzymatic Approaches for Polymer Conjugation to Proteins.

  2018cites this paper
• Molecular cloning, expression, and characterization of UDP N-acetyl-α-d-galactosamine: Polypeptide N-acetylgalactosaminyltransferase 4 from Cryptosporidium parvum.

  2018cites this paper
• Biocatalytic Synthesis of Fungal β-Glucans

  2018cites this paper
• p.R180C mutation of glycosyltransferase B leads to B subgroup, an in vitro and in silico study

  2018cites this paper
• The sugar code: Why glycans are so important

  2017cites this paper
• Making Home Sweet and Sturdy: Toxoplasma gondii ppGalNAc-Ts Glycosylate in Hierarchical Order and Confer Cyst Wall Rigidity

  2017cites this paper
• Expression and Purification of Glycosyltransferases in Pichia Pastoris: Towards Improving the Migration of Stem Cells by Enhancing Surface Expression of Sialyl Lewis X

  2017cites this paper
• Synthesis of homogeneous N-glycosylated- and GPI-anchored peptides for semi-synthesis of the prion protein

  2017cites this paper
• ' ' Title N-acetylglucosaminyltransferase I Activity of Bovine Oviduct Epithelial Cells : Stimulation by Luteinizing Hormone , Vascular Endothelial Growth Factor and Tumor Necrosis Factor α

  2017cites this paper
• Next Generation Sequencing-Based Genotyping of Human Blood Groups: FY, JK and ABO Genes

  2017influential citation
• Human glycosylation enzymes for enzymatic , structural and functional studies

  2017cites this paper
• Tools for Studying Glycans: Recent Advances in Chemoenzymatic Glycan Labeling.

  2017cites this paper
• Reduced Potency and Incomplete Neutralization of Broadly Neutralizing Antibodies against Cell-to-Cell Transmission of HIV-1 with Transmitted Founder Envs

  2017cites this paper
• The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs

  2017cites this paper
• The neutral N‐linked glycans of the ustilaginomycete yeast Sympodiomycopsis paphiopedili

  2017cites this paper
• HYDROLYSIS OF GLYCOSPHINGOLIPIDS BY BACTERIAL GLYCOSIDE HYDROLASES

  2017cites this paper
• Glycosyltransferases and non-alcoholic fatty liver disease.

  2016cites this paper
• Tumor Associated Carbohydrate Antigens in Targeted Therapy

  2016cites this paper
• Therapeutic Potential to Modify the Mucus Barrier in Inflammatory Bowel Disease

  2016cites this paper
• Molecular Evolution of the Glycosyltransferase 6 Gene Family in Primates

  2016cites this paper
• Commentary: Oil degradation and biosurfactant production by the deep sea bacterium Dietzia maris As-13-3

  2016cites this paper
• The role of heparan sulfate proteoglycans during development of the zebrafish lateral line

  2016cites this paper
• Expression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coli

  2016cites this paper
• Expression of key glycosphingolipid biosynthesis-globo series pathway genes in Escherichia coli F18-resistant and Escherichia coli F18-sensitive piglets.

  2016cites this paper