Mitochondrial DNA Replication: What We Know

No abstract is available for this paper.

• Publication year

  2003

• Venue

  IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/1521654031000134824PMID 12880201
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice.

  2003influential reference
• Human mitochondrial DNA with large deletions repopulates organelles faster than full-length genomes under relaxed copy number control.

  2002cited by this paper
• Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

  2002influential reference
• Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

  2000cited by this paper
• Mitochondrial DNA maintenance in vertebrates.

  1997cited by this paper
• In Vivo Determination of Replication Origins of Human Mitochondrial DNA by Ligation-mediated Polymerase Chain Reaction*

  1997cited by this paper
• The localization of replication origins on ARS plasmids in S. cerevisiae.

  1987cited by this paper
• Replication of animal mitochondrial DNA.

  1982cited by this paper
• Nucleotide assignment of alkali-sensitive sites in mouse mitochondrial DNA.

  1981cited by this paper
• Mechanism of mitochondrial DNA replication in mouse L cells: localization of alkali-sensitive sites at the two origins of replication.

  1981cited by this paper
• Mechanism of replication of human mitochondrial DNA. Localization of the 5' ends of nascent daughter strands.

  1981cited by this paper
• Analysis of the two heavy and light strand origins and the direction of replication of mitochondrial DNA within a detailed physical map of this genome in transformed hamster cells.

  1980cited by this paper
• Pulse-label analysis and mapping of the two terminal regions of asynchronous complementary strand replication of mitochondrial DNA in transformed hamster cells.

  1980cited by this paper
• Replication of mouse L-cell mitochondrial DNA.

  1979influential reference
• Localization of the ribonucleotide sites in rat liver mitochondrial deoxyribonucleic acid.

  1978cited by this paper
• Replication of mitochondrial DNA: replicative forms of molecules from rat tissues and evidence for discontinuous replication.

  1974cited by this paper
• Ribonucleotides in closed circular mitochondrial DNA from HeLa cells.

  1973cited by this paper
• The presence of ribonucleotides in mature closed-circular mitochondrial DNA.

  1973cited by this paper
• Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells.

  1972cited by this paper
• A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells.

  1967cited by this paper

• Mitochondrial Gene Phylogenetic Incongruencies Are Linked to Chromosomal Position and Function

  2025cites this paper
• Paradoxical Evolution of Apis mellifera Mitogenomes: Deviation From the Mutation-Selection-Drift Balance.

  2025cites this paper
• The Complicated Nature of Somatic mtDNA Mutations in Aging

  2022cites this paper
• Mitochondrial DNA: cellular genotoxic stress sentinel.

  2021cites this paper
• Mitochondrial genome of the critically endangered Baer’s Pochard, Aythya baeri, and its phylogenetic relationship with other Anatidae species

  2021cites this paper
• Mitochondrial epigenetics: an unnoticed phenomenon in mitochondrial gene expression

  2020cites this paper
• Evaluation of non-coding region sequence variants and mitochondrial haplogroups as potential biomarkers of sporadic breast cancer in individuals of Sri Lankan Sinhalese ethnicity.

  2020cites this paper
• mtDNA non‐coding region mutations and mitochondrial haplogroups as potential biomarkers of sporadic breast cancer in Sri Lankan Sinhalese women. Mitochondrial macro‐haplogroups were determined using PCR‐restriction fragment length polymorphism, whereas non‐coding region sequences were determined usi

  2020influential citation
• Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

  2019cites this paper
• Biological Functions of Novel Mitochondrial Proteins

  2019cites this paper
• Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner

  2018cites this paper
• CHAPTER 2 Molecular Biology of the OXPHOS System

  2018cites this paper
• Functional Variation In The Mitochondrial Genome Of The Yeast Saccharomyces Cerevisiae

  2018cites this paper
• Current strategies towards therapeutic manipulation of mtDNA heteroplasmy.

  2017cites this paper
• Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes

  2017cites this paper
• Study of RPC32α, subunit of the RNA polymerase III, in a tumor model

  2017cites this paper
• Regulation of mitochondrial gene expression, the epigenetic enigma.

  2017cites this paper
• Evolution of Nucleotide Punctuation Marks: From Structural to Linear Signals

  2017cites this paper
• An Introduction to Mitochondria, Their Structure and Functions

  2016cites this paper
• Molecular insights into mitochondrial transcription and its role in DNA replication

  2016cites this paper
• Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE

  2016cites this paper
• Structure and biophysical studies of mitochondrial Transcription Factor A in complex with DNA

  2016cites this paper
• Déficits de la chaîne respiratoire mitochondriale avec instabilité de l’ADN mitochondrial : identification de nouveaux gènes et mécanismes

  2016cites this paper
• Mitochondrial DNA alteration and pathological progression in colorectal cancer

  2016cites this paper
• The complete mitochondrial genome of the Zacco platypus, Huangshan, China (Cypriniformes: Cyprinidae, subfamily Daninninae)

  2015cites this paper
• Mitochondrial matrix processes

  2015cites this paper
• Ex vivo and in vitro models to study the effects of hypoxia and inflammation on human placental mitochondria

  2015cites this paper
• Concerted Evolution of Duplicate Control Regions in the Mitochondria of Species of the Flatfish Family Bothidae (Teleostei: Pleuronectiformes)

  2015cites this paper
• Mitochondrial Genetic Manipulation

  2015cites this paper
• The complete mitochondrial genome of the Acrossocheilus fasciatus (Cyprinidae, Barbinae)

  2015cites this paper
• Signal Transduction Pathways That Regulate Mitochondrial Gene Expression

  2015cites this paper
• A Rolling Circle Replication Mechanism Produces Multimeric Lariats of Mitochondrial DNA in Caenorhabditis elegans

  2015cites this paper
• A novel model of double replications and random loss accounts for rearrangements in the Mitogenome of Samariscus latus (Teleostei: Pleuronectiformes)

  2014cites this paper
• The largest unassigned regions of the male- and female-transmitted mitochondrial DNAs in Musculista senhousia (Bivalvia Mytilidae).

  2014cites this paper
• Mitochondrial DNA haplogroup-dependence of drugs and xenobiotics toxicity

  2014cites this paper
• Clinical and Molecular Genetic Studies in Mitochondrial Disease

  2014cites this paper
• Genetics of mitochondrial respiratory chain deficiencies.

  2014cites this paper
• Mitochondrial function and mitochondrial DNA maintenance with advancing age

  2014cites this paper
• The Arabidopsis At1g30680 gene encodes a homologue to the phage T7 gp4 protein that has both DNA primase and DNA helicase activities

  2013cites this paper
• Genetic aspects of mitochondrial genome evolution.

  2013cites this paper
• Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective

  2012cites this paper
• Mitochondrial targeting of recombinant RNAs modulates the level of a heteroplasmic mutation in human mitochondrial DNA associated with Kearns Sayre Syndrome

  2012cites this paper
• Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

  2012cites this paper
• Effets du rayonnement ultraviolet a sur la réplication de l’adn chez les eucaryotes supérieurs

  2012cites this paper
• Transcriptional Control of Striated Muscle Mitochondrial Biogenesis and Function

  2012cites this paper
• Mitochondrial DNA deletions are associated with non-B DNA conformations

  2012cites this paper
• Effects of X-irradiation on mitochondrial DNA damage and its supercoiling formation change.

  2011cites this paper
• Enlightenment of Yeast Mitochondrial Homoplasmy: Diversified Roles of Gene Conversion

  2011cites this paper
• Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC

  2011cites this paper
• Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle.

  2011cites this paper
• Human diseases with impaired mitochondrial protein synthesis.

  2011cites this paper
• Pathogenic mechanisms in mitochondrial optic neuropathies

  2011cites this paper
• angiogenesis in skeletal muscle transformation, mitochondrial biogenesis, and Regulation of exercise-induced fiber type

  2011cites this paper
• Solar Radiation Damage to Human Skin Mitochondria

  2010cites this paper
• Genetic bases of mitochondrial respiratory chain disorders.

  2010cites this paper
• Fluorescent in situ hybridization of mitochondrial DNA and RNA.

  2010cites this paper
• Martina Pejznochová The study of mitochondrial biogenesis during fetal development

  2010cites this paper
• Mitochondrial genome and human mitochondrial diseases

  2010cites this paper
• Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

  2009cites this paper
• Identification and characterization of mitochondrial genome concatemers in AIDS-associated lymphomas and lymphoma cell lines

  2009influential citation
• Mathematical Modeling of the Aging Process

  2009cites this paper
• Transgenic cardiac targeted overexpression of human thymidylate kinase (TMPK)

  2009cites this paper
• Identification of mitochondrial genome concatemers in AIDS-associated lymphomas and lymphoid cell lines.

  2009cites this paper
• Functional Characterization of a Bidirectional Mammalian Promoter of Two Genes for the Mitochondrial Translational Apparatus

  2009cites this paper
• Number matters: control of mammalian mitochondrial DNA copy number.

  2009cites this paper
• 'Why genomes in pieces?' revisited: sucking lice do their own thing in mtDNA circle game.

  2009cites this paper
• The structure of the Australian and South American marsupial mitochondrial control region

  2009cites this paper
• The pathophysiology of mitochondrial disease as modeled in the mouse.

  2009cites this paper
• Mitochondrial DNA haplogroups and subhaplogroups are associated with Parkinson’s disease risk in a Polish PD cohort

  2008cites this paper
• Lesions of the mitochondrial genome and ways of its preservation

  2008cites this paper
• Transcriptional paradigms in mammalian mitochondrial biogenesis and function.

  2008cites this paper
• Native R-loops Persist throughout the Mouse Mitochondrial DNA Genome

  2008cites this paper
• Sequence variations of mitochondrial DNA D-loop region are highly frequent events in familial breast cancer.

  2008cites this paper
• The Mitochondrial Genome of a Deep-Sea Bamboo Coral (Cnidaria, Anthozoa, Octocorallia, Isididae): Genome Structure and Putative Origins of Replication Are Not Conserved Among Octocorals

  2008influential citation
• Resource Letter: Bio-molecular Nano-machines: where Physics, Chemistry, Biology and Technology meet

  2008cites this paper
• Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients

  2007cites this paper
• Functional and structural characterization of the human mitochondrial helicase

  2007cites this paper
• Molecular and cell phenotype changes in mitochondrial diseases

  2007cites this paper
• Roles for the Human ATP-dependent Lon Protease in Mitochondrial DNA Maintenance*

  2007cites this paper
• Characterization of mitochondrial replication and transcription control during rat early development in vivo and in vitro.

  2007cites this paper
• Multiple origins and rapid evolution of duplicated mitochondrial genes in parthenogenetic geckos (Heteronotia binoei; Squamata, Gekkonidae).

  2007cites this paper
• Mutations of mitochondrial DNA polymerase gamma: an important cause of neurological disorders

  2007cites this paper
• Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA

  2007cites this paper
• Requirements and Standards for Organelle Genome Databases

  2006cites this paper
• Intraspecific Phylogeography of the Least Brook Lamprey

  2006cites this paper
• Genesis and Wanderings: Origins and Migrations in Asymmetrically Replicating Mitochondrial DNA

  2006cites this paper
• Control of Mitochondrial Transcription Specificity Factors (TFB1M and TFB2M) by Nuclear Respiratory Factors (NRF-1 and NRF-2) and PGC-1 Family Coactivators

  2005cites this paper
• On the relevance of mitochondrial fusions for the accumulation of mitochondrial deletion mutants: A modelling study

  2005cites this paper
• The evolution of mitochondrial genome structure and function in insects

  2005cites this paper
• Mitochondrial hTERT exacerbates free‐radical‐mediated mtDNA damage

  2004cites this paper
• Molecular Biology of the OXPHOS System

  2004cites this paper
• The Mitochondrial Genome and Human Mitochondrial Diseases

  2002cites this paper