Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Oncogene

• Publication date

  2011-09-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/onc.2011.103PMID 21460851
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival

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  2009influential reference
• The Fbxw7/hCdc4 tumor suppressor in human cancer.

  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
• SV40 small T antigen and PP2A phosphatase in cell transformation

  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  2007influential reference
• Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles.

  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2004influential reference
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  2004cited by this paper
• The functions of animal microRNAs

  2004cited by this paper
• SV40 early region oncoproteins and human cell transformation.

  2003cited by this paper
• Enumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation

  2002influential reference
• Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.

  2001cited by this paper
• The role of the SV40 ST antigen in cell growth promotion and transformation.

  2001cited by this paper
• Cellular transformation by SV40 large T antigen: interaction with host proteins.

  2001cited by this paper
• Critical role for SV40 small-t antigen in human cell transformation.

  2001cited by this paper
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  2001cited by this paper
• DNA copy number losses in human neoplasms.

  1999cited by this paper
• Creation of human tumour cells with defined genetic elements

  1999cited by this paper
• Regulation by tumour antigens defines a role for PP2A in signal transduction.

  1995cited by this paper
• Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication

  1994cited by this paper
• The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

  1993cited by this paper
• Independent expression of the transforming amino‐terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.

  1993cited by this paper
• Protein phosphatase 2A1 is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases.

  1993cited by this paper
• Control of protein phosphatase 2A by simian virus 40 small-t antigen

  1991cited by this paper
• Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

  1990cited by this paper
• The structure and regulation of protein phosphatases.

  1989cited by this paper
• Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene.

  1988cited by this paper
• Requirement for the simian virus 40 small tumor antigen in tumorigenesis in transgenic mice

  1988cited by this paper
• Translational regulation of SV40 early mRNA defines a new viral protein.

  1987cited by this paper
• Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts

  1987cited by this paper
• Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells.

  1978cited by this paper
• Organization and expression of early genes of simian virus 40.

  1978cited by this paper
• Construction and analysis of viable deletion mutants of simian virus 40

  1976cited by this paper
• Proliferation

  1966cited by this paper

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