γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Investigative Dermatology

• Publication date

  2013-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/jid.2012.372PMID 23096707
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The off-label treatment of severe hidradenitis suppurativa with TNF-α inhibitors: a systematic review

  2013cited by this paper
• Two novel mutations of the NCSTN gene in Chinese familial acne inverse

  2013influential reference
• A novel splice site mutation in NCSTN underlies a Japanese family with hidradenitis suppurativa

  2013influential reference
• Mutant Presenilin 2 Increases &bgr;-Secretase Activity Through Reactive Oxygen Species–Dependent Activation of Extracellular Signal–Regulated Kinase

  2012cited by this paper
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  2012influential reference
• Comparing treatment outcome of infliximab and adalimumab in patients with severe hidradenitis suppurativa

  2012cited by this paper
• Mutations in the γ-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa).

  2012influential reference
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  2011cited by this paper
• Confirmation by exome sequencing of the pathogenic role of NCSTN mutations in acne inversa (hidradenitis suppurativa).

  2011influential reference
• Elevated levels of tumour necrosis factor (TNF)‐α, interleukin (IL)‐1β and IL‐10 in hidradenitis suppurativa skin: a rationale for targeting TNF‐α and IL‐1β

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2010cited by this paper
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• Hidradenitis suppurativa: a comprehensive review.

  2009cited by this paper
• Lymph Nodes in Hidradenitis Suppurativa

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• Increased serum tumour necrosis factor-alpha in hidradenitis suppurativa patients: is there a basis for treatment with anti-tumour necrosis factor-alpha agents?

  2009cited by this paper
• Epidermal Notch signalling: differentiation, cancer and adhesion

  2008cited by this paper
• Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies.

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  2005cited by this paper
• gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.

  2004influential reference
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• The prevalence of hidradenitis suppurativa and its potential precursor lesions.

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  1995cited by this paper
• Hidradenitis suppurativa: a disease of follicular epithelium, rather than apocrine glands

  1990cited by this paper
• Endocrine basis for the clinical presentation of hidradenitis suppurativa

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• A family study of hidradenitis suppurativa.

  1985cited by this paper
• Pregnancy and apocrine gland diseases: hidradenitis, Fox-Fordyce disease.

  1952cited by this paper

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