The role of the Ran GTPase pathway in cell cycle control and interphase nuclear functions.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Progress in cell cycle research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-1-4615-1809-9_13PMID 9552361
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The RCC1 Protein Interacts with Ran, RanBP1, hsc70, and a 340-kDa Protein in Xenopus Extracts (*)

  1995cited by this paper
• A mutation in the RCC1-related protein pim1 results in nuclear envelope fragmentation in fission yeast.

  1995cited by this paper
• The nuclear GTPase cycle: promoting peripheralization?

  1995cited by this paper
• Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression

  1995cited by this paper
• The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motif.

  1995cited by this paper
• The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.

  1995cited by this paper
• Co‐activation of RanGTPase and inhibition of GTP dissociation by Ran‐GTP binding protein RanBP1.

  1995cited by this paper
• Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport.

  1995cited by this paper
• Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form

  1995cited by this paper
• Ran-binding Protein-1 Is an Essential Component of the Ran/RCC1 Molecular Switch System in Budding Yeast (*)

  1995cited by this paper
• Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules.

  1994cited by this paper
• Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

  1994cited by this paper
• A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation.

  1994cited by this paper
• A fission yeast RCC1‐related protein is required for the mitosis to interphase transition.

  1994cited by this paper
• A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

  1994cited by this paper
• nup1 mutants exhibit pleiotropic defects in nuclear pore complex function

  1994cited by this paper
• RanGAP1 induces GTPase activity of nuclear Ras-related Ran.

  1994cited by this paper
• The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B.

  1994cited by this paper
• A murine homolog of the yeast RNA1 gene is required for postimplantation development.

  1994cited by this paper
• Purification of a Ran-interacting protein that is required for protein import into the nucleus.

  1994cited by this paper
• mRNA nuclear export.

  1994cited by this paper
• Loss of RCC1 leads to suppression of nuclear protein import in living cells.

  1994cited by this paper
• Yeast homologue of mammalian Ran binding protein 1.

  1994cited by this paper
• A small nuclear GTP-binding protein from tomato suppresses a Schizosaccharomyces pombe cell-cycle mutant.

  1994cited by this paper
• A G protein involved in nucleocytoplasmic transport: the role of Ran.

  1994cited by this paper
• Effects of mutant Ran/TC4 proteins on cell cycle progression

  1994cited by this paper
• NuMA is required for the proper completion of mitosis

  1993cited by this paper
• Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis

  1993cited by this paper
• The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

  1993cited by this paper
• Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

  1993cited by this paper
• Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

  1993cited by this paper
• Proteins regulating Ras and its relatives

  1993cited by this paper
• A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.

  1993cited by this paper
• Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase.

  1993cited by this paper
• Nuclear PRP20 protein is required for mRNA export.

  1993cited by this paper
• RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles.

  1993cited by this paper
• GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization

  1993cited by this paper
• Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.

  1993cited by this paper
• Exercising self-restraint: discouraging illicit acts of S and M in eukaryotes.

  1993cited by this paper
• Prp20, the Saccharomyces cerevisiae homolog of the regulator of chromosome condensation, RCC1, interacts with double-stranded DNA through a multi-component complex containing GTP-binding proteins.

  1993cited by this paper
• Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.

  1993cited by this paper
• Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm.

  1992cited by this paper
• Developmental switch of CREM function during spermatogenesis: from antagonist to activator

  1992cited by this paper
• Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.

  1992cited by this paper
• RCC1, a regulator of mitosis, is essential for DNA replication

  1992cited by this paper
• DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication.

  1992cited by this paper
• Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

  1991cited by this paper
• Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

  1991cited by this paper
• The yeast SRM1 protein and human RCC1 protein share analogous functions.

  1991cited by this paper
• Loss of RCC1, a nuclear DNA‐binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

  1991cited by this paper
• Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae.

  1991cited by this paper
• Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.

  1991cited by this paper
• Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus.

  1990cited by this paper
• An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore

  1990cited by this paper
• A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

  1990cited by this paper
• Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

  1990cited by this paper
• Nuclear transport kinetics depend on phosphorylation‐site‐containing sequences flanking the karyophilic signal of the Simian virus 40 T‐antigen.

  1989cited by this paper
• Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants

  1989cited by this paper
• Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

  1989cited by this paper
• Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes

  1989cited by this paper
• The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

  1989cited by this paper
• Isolation of cDNA coding for the placental protein 15 (PP15).

  1988cited by this paper
• Periodic mitotic events induced in the absence of DNA replication.

  1987cited by this paper
• Exposure to caffeine and suppression of DNA replication combine to stabilize the proteins and RNA required for premature mitotic events

  1987cited by this paper
• The synthesis of protein(S) for chromosome condensation may be regulated by a post‐transcriptional mechanism

  1981cited by this paper
• Premature chromosome condensation in a ts DNA-mutant of BHK cells

  1978cited by this paper

• G-proteins | Ran GTPase

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  2003cites this paper
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  2002cites this paper
• Fission yeast Mog1p homologue, which interacts with the small GTPase Ran, is required for mitosis-to-interphase transition and poly(A)(+) RNA metabolism.

  2001cites this paper
• The Ran‐GTPase and cell‐cycle control

  2000cites this paper
• Ribavirin-induced resistance to heat shock, inhibition of the Ras-Raf-1 pathway and arrest in G(1).

  2000cites this paper
• Isolated mammalian and Schizosaccharomyces pombe ran-binding domains rescue S. pombe sbp1 (RanBP1) genomic mutants.

  1999cites this paper
• Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran.

  1999cites this paper
• A liver nuclear ethanol metabolizing system. Formation of metabolites that bind covalently to macromolecules and lipids.

  1999cites this paper
• Isolation and characterization of fission yeast sns mutants defective at the mitosis-to-interphase transition.

  1998cites this paper
• NUCLEAR STRUCTURE '98 Nuclear Transport: Run by Ran?

  1998cites this paper
• Nuclear transport: run by Ran?

  1998cites this paper
• RanBP2 associates with Ubc9p and a modified form of RanGAP1.

  1997cites this paper
• Perturbations in the spi1p GTPase cycle of Schizosaccharomyces pombe through its GTPase-activating protein and guanine nucleotide exchange factor components result in similar phenotypic consequences

  1996cites this paper