Voltage‐ and use‐dependent inhibition of Na+ channels in rat sensory neurones by 4030W92, a new antihyperalgesic agent

No abstract is available for this paper.

• Publication year

  1998

• Venue

  British Journal of Pharmacology

• Publication date

  1998-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1038/sj.bjp.0701919PMID 9692781PMCID PMC1565468
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Voltage‐ and use‐dependent inhibition of Na+ channels in rat sensory neurones by 4030W92, a new antihyperalgesic agent

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• Spinal sensory neurons express multiple sodium channel α-subunit mRNAs

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• A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

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• Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy.

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• Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons.

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• Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons

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• P-type calcium channels in rat central and peripheral neurons.

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• The use of oral mexiletine for the treatment of pain after peripheral nerve injury.

  1992cited by this paper
• Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs.

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