Age and energy intake interact to modify cell stress pathways and stroke outcome

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Annals of Neurology

• Publication date

  2010-01-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1002/ana.21798PMID 20186857PMCID PMC2844782
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals.

  2009cited by this paper
• Dietary restriction started after spinal cord injury improves functional recovery.

  2008cited by this paper
• A molecular chaperone inducer protects neurons from ER stress

  2008cited by this paper
• Immunoaffinity capillary electrophoresis as a powerful strategy for the quantification of low‐abundance biomarkers, drugs, and metabolites in biological matrices

  2008cited by this paper
• Strategies for use of IL‐10 or its antagonists in human disease

  2008cited by this paper
• Food restriction induces long-lasting recovery of spatial memory deficits following global ischemia in delayed matching and non-matching-to-sample radial arm maze tasks.

  2008cited by this paper
• Communication between the synapse and the nucleus in neuronal development, plasticity, and disease.

  2008cited by this paper
• Intravenous Brain-Derived Neurotrophic Factor Enhances Poststroke Sensorimotor Recovery and Stimulates Neurogenesis

  2007cited by this paper
• Interleukin‐17 as an Effector Molecule of Innate and Acquired Immunity against Infections

  2007cited by this paper
• Corrigendum to “Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma” [Free Radic. Biol. Med. 42 (2007) 665–674]

  2007cited by this paper
• Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.

  2007cited by this paper
• Analysis of inflammatory biomarkers from tissue biopsies by chip‐based immunoaffinity CE

  2007cited by this paper
• Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.

  2007cited by this paper
• Heme oxygenase-1 protects brain from acute excitotoxicity.

  2006cited by this paper
• Stroke upregulates TNFalpha transport across the blood-brain barrier.

  2006cited by this paper
• Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers.

  2006cited by this paper
• Activation of the Keap1 Nrf2 pathway for neuroprotection by electrophillic phase II inducers

  2006cited by this paper
• Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke.

  2006cited by this paper
• The role of inflammation in CNS injury and disease

  2006cited by this paper
• Ageing and neuronal vulnerability

  2006cited by this paper
• Stroke upregulates TNFα transport across the blood–brain barrier

  2006cited by this paper
• Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke

  2006cited by this paper
• Caloric restriction does not reverse aging-related changes in hippocampal BDNF.

  2005cited by this paper
• Conversion of Ischemic Brain Tissue Into Infarction Increases With Age

  2005cited by this paper
• IL‐6: an early marker for outcome in acute ischemic stroke

  2005cited by this paper
• The excitoprotective effect of N‐methyl‐d‐aspartate receptors is mediated by a brain‐derived neurotrophic factor autocrine loop in cultured hippocampal neurons

  2005cited by this paper
• Molecular Mechanisms Involved in Enhancing HO-1 Expression: De-Repression by Heme and Activation by Nrf2, The "One-Two" Punch

  2005cited by this paper
• Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip‐based immunoaffinity electrophoresis

  2004cited by this paper
• Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease

  2004cited by this paper
• Induction of GRP78 by Ischemic Preconditioning Reduces Endoplasmic Reticulum Stress and Prevents Delayed Neuronal Cell Death

  2003cited by this paper
• Levels of Anti-Inflammatory Cytokines and Neurological Worsening in Acute Ischemic Stroke

  2003cited by this paper
• Nasal Vaccination with Myelin Oligodendrocyte Glycoprotein Reduces Stroke Size by Inducing IL-10-Producing CD4+ T Cells1

  2003cited by this paper
• Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor.

  2003cited by this paper
• Stroke: molecular mechanisms and potential targets for treatment.

  2003cited by this paper
• Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

  2003cited by this paper
• Reduction of infarct volume and apoptosis by grafting of encapsulated basic fibroblast growth factor-secreting cells in a model of middle cerebral artery occlusion in rats.

  2003cited by this paper
• Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans.

  2003cited by this paper
• Calcium regulation of neuronal gene expression

  2001cited by this paper
• Targeted hsp70.1 Disruption Increases Infarction Volume After Focal Cerebral Ischemia in Mice

  2001cited by this paper
• IL-17 and IFN-γ mRNA expression is increased in the brain and systemically after permanent middle cerebral artery occlusion in the rat

  2001cited by this paper
• Interleukin‐10 modulates neuronal threshold of vulnerability to ischaemic damage

  2000cited by this paper
• Ischemic Brain Damage in Mice after Selectively Modifying BDNF or NT4 Gene Expression

  2000cited by this paper
• Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction

  2000cited by this paper
• The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

  1999cited by this paper
• Potential Usefulness of Basic Fibroblast Growth Factor as a Treatment for Stroke

  1999cited by this paper
• Dietary restriction and 2‐deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism

  1999cited by this paper
• Overexpression of Heme Oxygenase‐1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice

  1999cited by this paper
• Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults

  1999cited by this paper
• Inflammatory Mediators and Stroke: New Opportunities for Novel Therapeutics

  1999cited by this paper
• Electrophysiological transcortical diaschisis after middle cerebral artery occlusion (MCAO) in rats.

  1999cited by this paper
• Interleukin‐10 Inhibits Both Production of Cytokines and Expression of Cytokine Receptors in Microglia

  1999cited by this paper
• Temporal Profile and Cellular Localization of Interleukin-6 Protein after Focal Cerebral Ischemia in Rats

  1999cited by this paper
• Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats.

  1997cited by this paper
• Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.

  1997cited by this paper
• Heat shock factor-1 protein in heat shock factor-1 gene-transfected human epidermoid A431 cells requires phosphorylation before inducing heat shock protein-70 production.

  1997cited by this paper
• Marked age‐dependent neuroprotection by brain‐derived neurotrophic factor against neonatal hypoxic—ischemic brain injury

  1997cited by this paper
• Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

  1996cited by this paper
• Hypoglycemia-induced AP-1 transcription factor and basic fibroblast growth factor gene expression in multidrug resistant human breast carcinoma MCF-7/ADR cells

  1996cited by this paper
• Stress Proteins and Tolerance to Focal Cerebral Ischemia

  1996cited by this paper
• Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats.

  1995cited by this paper
• Kainic Acid‐induced Heat Shock Protein‐70, mRNA and Protein Expression is Inhibited by MK‐801 in Certain Rat Brain Regions

  1995cited by this paper
• Correlation Between Fibroblast Growth Factor Expression and Cell Proliferation in Experimental Brain Infarct: Studied with Proliferating Cell Nuclear Antigen Immunohistochemistry

  1994cited by this paper
• Stroke in the elderly

  1994cited by this paper
• Cerebral Oxygen Metabolism and Blood Flow in Human Cerebral Ischemic Infarction

  1982cited by this paper

• Intermittent fasting and ketone bodies.

  2025cites this paper
• A Prospective Observational Study of a 2-Week Integrative Inpatient Therapy on Patients with Fibromyalgia Syndrome

  2025cites this paper
• Time-restricted feeding prevents depressive-like behaviors by suppressing changes in the gut microbiota.

  2025cites this paper
• Every-Other-Day Feeding Prevents the Loss of Parvalbumin-Expressing Neurons in the Cerebral Cortex of Female 5xFAD Mice

  2025cites this paper
• The Role of Intermittent Fasting and Calorie Restriction in Preventing Neurodegenerative Diseases within the Context of Adult Neurogenesis

  2025cites this paper
• Hormesis and brain diseases.

  2025cites this paper
• Sunflower Oil Fortified with Vitamins D and A and Sunflower Lecithin Ameliorated Scopolamine-Induced Cognitive Dysfunction in Mice and Exploration of the Underlying Protective Pathways

  2025cites this paper
• The cyclic metabolic switching theory of intermittent fasting

  2025cites this paper
• Possible Role of Intermittent Fasting on Decreasing the Aging process on Well-controlled HIV patients on Antiretroviral therapy (ART)

  2024cites this paper
• Health Benefits of Intermittent Fasting

  2024cites this paper
• EPO modified MSCs protects SH-SY5Y cells against ischemia/hypoxia-induced apoptosis via REST-dependent epigenetic remodeling

  2024cites this paper
• The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice

  2024cites this paper
• The effects of fasting on acute ischemic infarcts in the rat

  2024cites this paper
• The impact of sodium nitrite and intermittent fasting on neurofilament and tau protein phosphorylation, and spatial learning in rat hippocampus

  2024cites this paper
• Intermittent fasting, fatty acid metabolism reprogramming, and neuroimmuno microenvironment: mechanisms and application prospects

  2024cites this paper
• The hormesis principle of neuroplasticity and neuroprotection.

  2024cites this paper
• Impact of Parental Time-Restricted Feeding on Offspring Metabolic Phenotypic Traits

  2024cites this paper
• Intermittent fasting alleviates postoperative cognitive dysfunction by reducing neuroinflammation in aged mice.

  2024cites this paper
• Effect of time-restricted eating and intermittent fasting on cognitive function and mental health in older adults: A systematic review

  2024cites this paper
• Intermittent Fasting Induced Cerebral Ischemic Tolerance Altered Gut Microbiome and Increased Levels of Short-Chain Fatty Acids to a Beneficial Phenotype.

  2024cites this paper
• Anxiolytic Action of Dipeptide Mimetic of the BDNF Loop 2 in Adult Animals

  2024cites this paper
• INTERMITTENT FASTING AND LONGEVITY: FROM ANIMAL MODELS TO IMPLICATION FOR HUMANS.

  2024cites this paper
• Intermittent fasting alerts neurotransmitters and oxidant/antioxidant status in the brain of rats

  2024cites this paper
• Alternate Day Fasting Leads to Improved Post-Stroke Motor Recovery in Mice

  2024influential citation
• A detective story of intermittent fasting effect on immunity

  2024cites this paper
• Intermittent fasting and neurodegenerative diseases: Molecular mechanisms and therapeutic potential.

  2024cites this paper
• Association between energy intake and activities of daily living in patients with acute stroke at hospital discharge: a retrospective cohort study

  2024cites this paper
• Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial

  2024cites this paper
• Intermittent Metabolic Switching and Vascular Cognitive Impairment

  2024influential citation
• Mechanisms of time-restricted feeding-induced neuroprotection and neuronal plasticity in ischemic stroke as a function of circadian rhythm.

  2024cites this paper
• Energy restriction inhibits β-catenin ubiquitination to improve ischemic stroke injury via USP18/SKP2 axis

  2024cites this paper
• Effects of intermittent fasting on cognitive health and Alzheimer’s disease

  2023cites this paper
• The Role of Intermittent Fasting and Dieting on Cognition in Adult Population: A Systematic Review of the Randomized Controlled Trials

  2023cites this paper
• Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

  2023cites this paper
• The regulatory effect of intermittent fasting on inflammasome activation in health and disease.

  2023cites this paper
• The Effect of Ramadan Fasting on the Immune System Function

  2023cites this paper
• Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular Diseases

  2023cites this paper
• Transcriptome Analysis of Cisplatin, Cannabidiol, and Intermittent Serum Starvation Alone and in Various Combinations on Colorectal Cancer Cells

  2023cites this paper
• Common and divergent molecular mechanisms of fasting and ketogenic diets.

  2023cites this paper
• The benefits of intermittent fasting: A review of possible mechanisms on central neurological disorders

  2023cites this paper
• Effects and possible mechanisms of intermittent fasting on health and disease: a narrative review.

  2023cites this paper
• Nutritional neurology: Unraveling cellular mechanisms of natural supplements in brain health

  2023cites this paper
• Intermittent Fasting Attenuates Hallmark Vascular and Neuronal Pathologies in a Mouse Model of Vascular Cognitive Impairment

  2022cites this paper
• Traditional and Medical Applications of Fasting

  2022cites this paper
• The association of diet carbohydrates consumption with cognitive function among US older adults modification by daily fasting duration

  2022cites this paper
• Dietary energy restriction in neurological diseases: what’s new?

  2022cites this paper
• Activity‐Dependent Induction of Younger Biological Phenotypes

  2022cites this paper
• Food Restriction Counteracts Dexamethasone-Induced Downregulation of Genes Involved in Cholesterol Homeostasis in Rat Brain during Aging

  2022cites this paper
• Absence of the bile acid enzyme CYP8B1 increases brain chenodeoxycholic acid and reduces neuronal excitotoxicity in mice

  2022cites this paper
• Evaluation of Neuropharmacological Effects of Ginger: A Narrative Review

  2022cites this paper
• Effect of intermittent fasting on saving zone of stasis in burn wounds in rats.

  2022cites this paper
• Functional fiber enhances the effect of every-other-day fasting on insulin sensitivity by regulating the gut microecosystem.

  2022cites this paper
• Antidiabetic Drugs and their Potential Use in COVID-19: A Mechanistic Approach.

  2022cites this paper
• Intermittent Fasting: Potential Utility in the Treatment of Chronic Pain across the Clinical Spectrum

  2022influential citation
• Intermittent Fasting Mitigates Vascular and Neuronal Pathologies in a Mouse Model of Vascular Dementia

  2022cites this paper
• Effect of Ramadan fasting on salivary IgA, serum IgA, IL-17, and IL-22 levels

  2022cites this paper
• Effects of Intermittent Fasting on Brain Metabolism

  2022cites this paper
• Neutrophil dynamics and inflammaging in acute ischemic stroke: A transcriptomic review

  2022cites this paper
• Systematic Review ‐ Neuroprotection of ketosis in acute injury of the mammalian central nervous system: A meta‐analysis

  2021cites this paper
• Late-Onset, Short-Term Intermittent Fasting Reverses Age-Related Changes in Calcium Buffering and Inhibitory Synaptic Transmission in Mouse Basal Forebrain Neurons

  2021cites this paper
• The Impact of Intermittent Fasting on Brain-Derived Neurotrophic Factor, Neurotrophin 3, and Rat Behavior in a Rat Model of Type 2 Diabetes Mellitus

  2021cites this paper
• Much ado about eating: Intermittent fasting and post-stroke neuroprotection

  2021cites this paper
• Beneficial Effects on Brain Micro-Environment by Caloric Restriction in Alleviating Neurodegenerative Diseases and Brain Aging

  2021cites this paper
• Intermittent Fasting and Cognitive Performance - Targeting BDNF as Potential Strategy to Optimise Brain Health.

  2021cites this paper
• Elevated Neutrophil to Lymphocyte Ratio Associated With Increased Risk of Recurrent Vascular Events in Older Minor Stroke or TIA Patients

  2021cites this paper
• The role and its mechanism of intermittent fasting in tumors: friend or foe?

  2021cites this paper
• Potential role of intermittent fasting on decreasing cardiovascular disease in human immunodeficiency virus patients receiving antiretroviral therapy

  2021cites this paper
• Association between Time Restricted Feeding and Cognitive Status in Older Italian Adults

  2021cites this paper
• Increased Calbindin D28k Expression via Long-Term Alternate-Day Fasting Does Not Protect against Ischemia-Reperfusion Injury: A Focus on Delayed Neuronal Death, Gliosis and Immunoglobulin G Leakage

  2021cites this paper
• Nerve injury and repair in a ketogenic milieu: A systematic review of traumatic injuries to the spinal cord and peripheral nervous tissue

  2021cites this paper
• The Effects of Intermittent Fasting on Brain and Cognitive Function

  2021cites this paper
• Intermittent Fasting Alleviates Cognitive Impairments and Hippocampal Neuronal Loss but Enhances Astrocytosis in Mice with Subcortical Vascular Dementia.

  2021cites this paper
• Mini review: The relationship between energy status and adult hippocampal neurogenesis

  2021cites this paper
• Health and Wellbeing: Bridging Secular and Islamic Worldviews

  2021cites this paper
• Intermittent fasting promotes anxiolytic-like effects unrelated to synaptic mitochondrial function and BDNF support.

  2021cites this paper
• Intermittent fasting attenuates inflammasome-associated apoptotic and pyroptotic death in the brain following chronic hypoperfusion.

  2021cites this paper
• The Influence of Intermittent Fasting Regimens on the Regulatory Mechanisms of Metabolic Health

  2021cites this paper
• Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

  2021cites this paper
• Differential weight loss with intermittent fasting or daily calorie restriction in low‐ and high‐fitness phenotypes

  2021cites this paper
• Toll-like receptor 4 signaling is critical for the adaptive cellular stress response effects induced by intermittent fasting in the mouse brain.

  2021cites this paper
• Intermittent and periodic fasting, longevity and disease

  2021cites this paper
• Dietary nutrition for neurological disease therapy: Current status and future directions.

  2021cites this paper
• Exosomes and Exosomal MicroRNAs in Age-Associated Stroke.

  2021cites this paper
• Is there any role of intermittent fasting in the prevention and improving clinical outcomes of COVID-19?: intersection between inflammation, mTOR pathway, autophagy and calorie restriction

  2021cites this paper
• Intermittent fasting in paediatric critical illness: The properties and potential beneficial effects of an overnight fast in the PICU.

  2021cites this paper
• Effects of dietary restriction on gut microbiota and CNS autoimmunity.

  2020cites this paper
• Hormesis: A potential strategic approach to the treatment of neurodegenerative disease.

  2020cites this paper
• Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors

  2020cites this paper
• Involvement of GABAergic interneuron dysfunction and neuronal network hyperexcitability in Alzheimer's disease: Amelioration by metabolic switching.

  2020cites this paper
• Creating a Lifestyle Medicine Center: From Concept to Clinical Practice

  2020cites this paper
• Effect of Time Restricted Feeding on Metabolic Risk and Circadian Rhythm Associated with Gut Microbiome in Healthy Males.

  2020cites this paper
• Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease.

  2020cites this paper
• A review of effects of calorie restriction and fasting with potential relevance to depression.

  2020cites this paper
• Time restricted feeding and mental health: a review of possible mechanisms on affective and cognitive disorders

  2020cites this paper
• Molecular Mechanisms of Intermittent Fasting-induced Ischemic Tolerance.

  2020cites this paper
• Metabolic regulation of aging and age-related disease.

  2020cites this paper
• Lifestyle Medicine Center for Brain Aging and Neurodegenerative Diseases

  2020cites this paper
• Muse Cells

  2020cites this paper
• Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition

  2020cites this paper
• Hippocampal Transcriptome Profiling Reveals Common Disease Pathways in Chronic Hypoperfusion and Ageing

  2020cites this paper