DAVID: Database for Annotation, Visualization, and Integrated Discovery

The distributed nature of biological knowledge poses a major challenge to the interpretation of genome-scale datasets, including those derived from microarray and proteomic studies. This report describes DAVID, a web-accessible program that integrates functional genomic annotations with intuitive graphical summaries. Lists of gene or protein identifiers are rapidly annotated and summarized according to shared categorical data for Gene Ontology, protein domain, and biochemical pathway membership. DAVID assists in the interpretation of genome-scale datasets by facilitating the transition from data collection to biological meaning.

• Publication year

  2003

• Venue

  Genome Biology

• Publication date

  2003-08-14

• Fields of study

  Biology, Computer Science

• Identifiers
  DOI 10.1186/gb-2003-4-9-r60PMCID 193660
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• DAVID is presented as a tool for helping move genome-scale datasets from data collection toward biological interpretation.

  Confidence 0.93

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• The annotation summaries are organized around Gene Ontology terms, protein domain information, and biochemical pathway membership.

  Confidence 0.95

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• Gene or protein identifier lists can be rapidly annotated and summarized by shared categorical data in DAVID.

  Confidence 0.96

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• DAVID provides a web-accessible resource that integrates functional genomic annotations with graphical summaries.

  Confidence 0.98

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review

• biochemical pathway membership

  annotation category, biological classification

  Assignment of a gene or protein to a biochemical pathway used for categorical grouping.

  Aliases: pathway membership

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• david

  web resource, software

  A web-accessible software resource for annotating gene or protein lists and presenting the results in summarized form.

  Aliases: Database for Annotation, Visualization, and Integrated Discovery

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• functional genomic annotations

  annotation data, biological annotation

  Annotation information that links genes or proteins to biological functions and related biological categories.

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• gene ontology

  ontology, controlled vocabulary

  A controlled vocabulary for describing gene and gene-product functions used as one annotation source.

  Aliases: GO

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• gene or protein identifiers

  biological entity list, input data

  Lists of gene or protein names used as input for annotation and summary analysis.

  Aliases: gene/protein identifiers, gene and protein identifiers

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• genome-scale datasets

  dataset, biological data

  Large biological datasets containing measurements across many genes or proteins.

  Aliases: genome-wide datasets

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review
• protein domain

  annotation category, protein feature

  A recurring structural or functional unit within a protein used as a categorical annotation feature.

  Aliases: protein domains

  박진우 (dztg5apj7m) extraction뀨 (7c402c1b98) reviewq (76h6bfydm6) reviewKiller Whale (322360f1c1) review

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