Relevance of the T cell receptor for immunotherapy of cancer

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Cancer Immunology and Immunotherapy

• Publication date

  1994-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/BF01517174PMID 8044821PMCID PMC11038863
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Preferential usage of T‐cell receptor αβ variable regions among tumor‐infiltrating lymphocytes in primary human malignant melanomas

  2007cited by this paper
• Squamous Cell Carcinoma of the Head and Neck Human Cytotoxic T-Cell Lines with Restricted Specificity for Updated

  2006cited by this paper
• Induction of human glioma-specific cytotoxic T-lymphocyte lines by autologous tumor stimulation and interleukin 2

  2005cited by this paper
• Cytotoxic activity and phenotypic characteristics of lymphocyte subsets after therapy of cancer patients with interleukin-2

  2005cited by this paper
• Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

  2005cited by this paper
• Clonal analysis of in vivo activated CD8+ cytotoxic T lymphocytes from a melanoma patient responsive to active specific immunotherapy

  2005cited by this paper
• The pattern of the mononuclear infiltrate as a prognostic parameter in flat superficial spreading melanomas

  2004cited by this paper
• Tumor vaccines

  2004cited by this paper
• Tumor antigens recognized by cytolytic T lymphocytes

  1995influential reference
• HLA restriction and T‐cell‐receptor Vβ gene expression of cytotoxic T lymphocytes reactive with human squamous‐cell carcinoma of the head and neck

  1994cited by this paper
• Preferential usage of T-cell receptor alpha beta variable regions among tumor-infiltrating lymphocytes in primary human malignant melanomas.

  1994cited by this paper
• Gene therapy of cancer: a pilot study of IL-4-gene-modified fibroblasts admixed with autologous tumor to elicit an immune response.

  1994cited by this paper
• Preferential usage of T-cell receptor alpha beta variable regions among tumor-infiltrating lymphocytes in primary human malignant melanomas.

  1994cited by this paper
• Differential expression of MAGE-1, -2, and -3 messenger RNA in transformed and normal human cell lines.

  1993cited by this paper
• Mechanism of lymphocyte-mediated cytolysis: functional cytolytic T cells lacking perforin and granzymes.

  1993cited by this paper
• lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

  1993cited by this paper
• T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2- restricted and melanocyte-lineage-specific CTL clone

  1993cited by this paper
• Mucin synthesis and secretion in various human epithelial cancer cell lines that express the MUC-1 mucin gene.

  1993cited by this paper
• Daily alternating administration of high‐dose alpha‐2b‐interferon and interleukin‐2 bolus infusion in metastatic renal cell cancer. A phase II study

  1993cited by this paper
• Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

  1993cited by this paper
• Tumor antigens recognized by cytolytic T lymphocytes: Present perspectives for specific immunotherapy

  1993cited by this paper
• gamma-Interferon plays a key role in T-cell-induced tumor regression.

  1993cited by this paper
• The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes

  1993cited by this paper
• Evidence for in situ amplification of cytotoxic T-lymphocytes with antitumor activity in a human regressive melanoma.

  1993cited by this paper
• Evidence for oligoclonal T-cell response in a metastasis of renal cell carcinoma responding to vaccination with autologous tumor cells and transfer of in vitro-sensitized vaccine-draining lymph node lymphocytes.

  1993cited by this paper
• Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion.

  1993cited by this paper
• T cell recognition of human tumors: implications for molecular immunotherapy of cancer.

  1993influential reference
• The basic science of gene therapy.

  1993cited by this paper
• Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.

  1993cited by this paper
• In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats.

  1993cited by this paper
• Transfection of interleukin 2 gene into human melanoma cells augments cellular immune response.

  1993cited by this paper
• Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer.

  1993influential reference
• Usage of T‐cell receptor Vβ chain genes in fresh and cultured tumor‐infiltrating lymphocytes from human melanoma

  1993cited by this paper
• Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

  1993cited by this paper
• Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ.

  1992cited by this paper
• Rapid cytokine release in cancer patients treated with interleukin-2.

  1992cited by this paper
• Expression of mRNA for cytokines in tumor‐infiltrating mononuclear cells in ovarian adenocarcinoma and invasive breast cancer

  1992cited by this paper
• The T-Cell Receptor Vβ Gene Usage in Tumor-infiltrating Lymphocytes and Blood of Patients with Hepatocellular Carcinoma

  1992cited by this paper
• MELANOMA IMMUNOGENICITY: MELANOMA CELLS PRESENT BOTH ENDOGENOUSLY—AND EXOGENOUSLY—DERIVED PEPTIDES TO CD8+ CYTOLYTIC T CELLS

  1992cited by this paper
• Interleukin‐2 in Association with Increasing Doses of Interferon‐Gamma in Patients with Advanced Cancer

  1992cited by this paper
• Improving responses in hepatomas with circadian-patterned hepatic artery infusions of recombinant interleukin-2.

  1992cited by this paper
• Analysis of T-Cell Receptor α/β Variability in Lymphocytes Infiltrating a Melanoma Metastasis

  1992cited by this paper
• Transfection of interferon-gamma gene in animal tumors--a model for local cytokine production and tumor immunity.

  1992cited by this paper
• A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability

  1992cited by this paper
• Characterization of lymphocytes infiltrating human breast cancer: specific immune reactivity detected by measuring cytokine secretion.

  1992cited by this paper
• Mutations defining functional regions of the superantigen staphylococcal enterotoxin B

  1992cited by this paper
• Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4.

  1992cited by this paper
• Generation of the alpha beta T-cell repertoire.

  1992cited by this paper
• Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential.

  1992cited by this paper
• Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas.

  1992cited by this paper
• Structural analysis of class II major histocompatibility complex proteins.

  1992cited by this paper
• VDJ recombination.

  1992cited by this paper
• Analysis of T-cell receptor alpha/beta variability in lymphocytes infiltrating a melanoma metastasis.

  1992cited by this paper
• The T-cell receptor V beta gene usage in tumor-infiltrating lymphocytes and blood of patients with hepatocellular carcinoma.

  1992cited by this paper
• Superantigens.

  1992cited by this paper
• Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

  1992cited by this paper
• Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.

  1992cited by this paper
• Superantigens.

  1992cited by this paper
• The development of functionally responsive T cells.

  1992cited by this paper
• Michael Heidelberger (1888–1991): Transition from life to legend

  1992cited by this paper
• Structural analysis of class II major histocompatibility complex proteins.

  1992cited by this paper
• Sequential chemotherapy and immunotherapy for the treatment of metastatic melanoma.

  1992cited by this paper
• Generation of the αβ T-cell repertoire

  1992cited by this paper
• A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E

  1992cited by this paper
• Signalling in human tumour infiltrating lymphocytes: the CD28 molecule is functional and is physically associated with the CD45R0 molecule.

  1992cited by this paper
• Tumor-infiltrating lymphocytes as antitumor effector cells

  1992cited by this paper
• Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin- derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition

  1992cited by this paper
• Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-gamma in irradiated human melanoma cells.

  1992cited by this paper
• Expression of tumor-associated epitopes on Epstein-Barr virus-immortalized B-cells and Burkitt's lymphomas transfected with epithelial mucin complementary DNA.

  1992cited by this paper
• Retroviral vector-mediated lymphokine gene transfer into human renal cancer cells.

  1992cited by this paper
• Characterization of a human renal cell carcinoma specific cytotoxic CD8+ T cell line.

  1992influential reference
• Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells.

  1991influential reference
• Staphylococcal exotoxins deliver activation signals to human T-cell clones via major histocompatibility complex class II molecules.

  1991cited by this paper
• Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional Vα subfamilies and 14 Jα gene segments

  1991cited by this paper
• Cellular and humoral immune responses against cancer: implications for cancer vaccines.

  1991cited by this paper
• Evidence of limited variability of antigen receptors on intrathyroidal T cells in autoimmune thyroid disease.

  1991cited by this paper
• Structure/function analysis of the invariant subunits of the T cell antigen receptor.

  1991influential reference
• Evidence for the effects of a superantigen in rheumatoid arthritis.

  1991cited by this paper
• An analysis of T‐cell‐receptor variable‐region genes in tumor‐infiltrating lymphocytes within malignant tumors

  1991cited by this paper
• A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.

  1991cited by this paper
• Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

  1991cited by this paper
• Cytotoxic T cell clones isolated from ovarian tumor-infiltrating lymphocytes recognize multiple antigenic epitopes on autologous tumor cells.

  1991influential reference
• Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional Vβ subfamilies

  1991cited by this paper
• Studies on the human T cell receptor alpha/beta variable region genes. I. Identification of 7 additional V alpha subfamilies and 14 J alpha gene segments.

  1991cited by this paper
• Staphylococcal enterotoxin-dependent cell-mediated cytotoxicity.

  1991cited by this paper
• Roles of multiple accessory molecules in T-cell activation.

  1991cited by this paper
• Characterization of human autotumor-reactive T-cell clones obtained from tumor-infiltrating lymphocytes in liver metastasis of gastric carcinoma.

  1991influential reference
• Staphylococcal-enterotoxin-dependent cell-mediated cytotoxicity.

  1991cited by this paper
• An endogenous retrovirus mediating deletion of alpha beta T cells?

  1991cited by this paper
• The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice

  1991cited by this paper
• Human T cell receptor gamma delta + T cells.

  1991cited by this paper
• An endogenous retrovirus mediating deletion of αβ T cells?

  1991cited by this paper
• T-cell-mediated cytotoxicity.

  1991cited by this paper
• Limited heterogeneity of rearranged T-cell receptor V α transcripts in brains of multiple sclerosis patients

  1991cited by this paper
• Studies on the human T cell receptor alpha/beta variable region genes. II. Identification of four additional V beta subfamilies.

  1991cited by this paper
• High-fold expansion of human cytotoxic T-lymphocytes specific for autologous melanoma cells for use in immunotherapy.

  1991cited by this paper
• Staphylococcal enterotoxin-dependent lysis of MHC class II negative target cells by cytolytic T lymphocytes.

  1991cited by this paper
• Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomes

  1991cited by this paper
• Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation.

  1991cited by this paper
• Autologous Tumor-Specific Cytotoxicity of Tumor-Infiltrating Lymphocytes Derived from Human Renal Cell Carcinoma

  1991cited by this paper

• TCRBV 14 in HLA-A 2-matched Primary Human Melanomas-Chain Variable Region β Overexpression of the T-Cell Receptor Updated

  2006cites this paper
• Retargeting of a T cell line by anti MAGE-3/HLA-A2 alpha beta TCR gene transfer.

  2000cites this paper
• Hepatosplenic T cell lymphoma. A review on 45 cases since the first report describing the disease as a distinct lymphoma entity in 1990

  2000cites this paper
• Immune monitoring of cancer patients undergoing experimental immunotherapy.

  2000cites this paper
• In vivo selective expansion of a tumour‐specific cytotoxic T‐cell clone derived from peripheral blood of a melanoma patient after vaccination with gene‐modified autologous tumour cells

  1999cites this paper
• Decreasing Extracellular pH Increases CD13 Receptor Surface Content and Alters the Metabolism of HL60 Cells Cultured in Stirred Tank Bioreactors

  1998cites this paper
• Increased agitation intensity increases CD13 receptor surface content and mRNA levels, and alters the metabolism of HL60 cells cultured in stirred tank bioreactors.

  1998cites this paper
• Report of immune monitoring of prostate cancer patients undergoing T‐cell therapy using dendritic cells pulsed with HLA‐A2‐specific peptides from prostate‐specific membrane antigen (PSMA)

  1998cites this paper
• Immunological characteristics of the effector cells induced by a combination therapy with cyclophosphamide and allogeneic lymphocytes.

  1998cites this paper
• Human cytotoxic CD8+ T-lymphocyte clones engraft in severe combined immunodeficient (SCID) mice but show diminished function.

  1997cites this paper
• Monitoring of Cancer Patients Undergoing Active or Passive Immunotherapy

  1997cites this paper
• Specific cytotoxic T lymphocytes in gene therapy

  1997cites this paper
• Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8.

  1997cites this paper
• Activation of T cell cytotoxicity against autologous common acute lymphoblastic leukemia (cALL) blasts by CD3xCD19 bispecific antibody.

  1996cites this paper
• Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity.

  1996cites this paper
• Elimination of established liver metastases by human interleukin 2-activated natural killer cells after locoregional or systemic adoptive transfer.

  1996cites this paper
• Overexpression of the T-cell receptor beta-chain variable region TCRBV14 in HLA-A2-matched primary human melanomas.

  1995cites this paper