Chronobesity: role of the circadian system in the obesity epidemic

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Obesity Reviews

• Publication date

  2016-02-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1111/obr.12351PMID 26693661
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Neurobiology of food anticipatory circadian rhythms.

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• Breakfast frequency and quality may affect glycemia and appetite in adults and children.

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