Nutrigenomics and Nutrigenetics

D. Farhud,M. Zarif Yeganeh,M. Zarif Yeganeh

Published 2010 in Iranian Journal of Public Health

ABSTRACT

The nutrients are able to interact with molecular mechanisms and modulate the physiological functions in the body. The Nutritional Genomics focuses on the interaction between bioactive food components and the genome, which includes Nutrigenetics and Nutrigenomics. The influence of nutrients on f genes expression is called Nutrigenomics, while the heterogeneous response of gene variants to nutrients, dietary components and developing nutraceticals is called Nutrigenetics. Genetic variation is known to affect food tolerances among human subpopulations and may also influence dietary requirements and raising the possibility of individualizing nutritional intake for optimal health and disease prevention on the basis of an individual’s genome. Nutrigenomics provides a genetic understanding for how common dietary components affect the balance between health and disease by altering the expression and/or structure of an individual’s genetic makeup. Nutrigenetics describes that the genetic profile have impact on the response of body to bioactive food components by influencing their absorption, metabolism, and site of action. In this way, considering different aspects of gene–nutrient interaction and designing appropriate diet for every specific genotype that optimize individual health, diagnosis and nutritional treatment of genome instability, we could prevent and control conversion of healthy phenotype to diseases.

PUBLICATION RECORD

  • Publication year

    2010

  • Venue

    Iranian Journal of Public Health

  • Publication date

    2010-12-31

  • Fields of study

    Biology, Agricultural and Food Sciences, Medicine

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar, PubMed

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