Long-term neurochemical and behavioral effects induced by acute chlorpyrifos treatment.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Pharmacology, Biochemistry and Behavior

• Publication date

  1992-06-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1016/0091-3057(92)90523-IPMID 1378635
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Repeated exposure to diisopropylfluorophosphate (DFP) produces increased sensitivity to cholinergic antagonists in discrimination retention and reversal

  2005cited by this paper
• Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides.

  1991cited by this paper
• Early development of muscarinic supersensitivity in a genetic animal model of depression.

  1991cited by this paper
• High-affinity activation by paraoxon of a muscarinic receptor subtype in rat brain striatum

  1991cited by this paper
• Relative potencies of agonists and differential sensitivity to N-ethylmaleimide on muscarinic autoreceptors and postsynaptic receptors in rat hippocampus.

  1990cited by this paper
• Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate.

  1990cited by this paper
• A comparison of the effects of cholinergic and dopaminergic agents on scopolamine-induced hyperactivity in mice.

  1990cited by this paper
• Depletion of catecholamines in the brain of rats differentially affects stimulation of locomotor activity by caffeine, D-amphetamine, and methylphenidate.

  1990cited by this paper
• Muscarinic modulation of endogenous acetylcholine release in rat neostriatal slices.

  1989cited by this paper
• Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes.

  1988cited by this paper
• Direct actions of organophosphate anticholinesterases on nicotinic and muscarinic acetylcholine receptors.

  1988cited by this paper
• Effects of scopolamine on locomotor activity and metabolic rate in mice.

  1987cited by this paper
• Identification of a family of muscarinic acetylcholine receptor genes.

  1987cited by this paper
• Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain.

  1986cited by this paper
• Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after direct labeling with [3H]-QNB and [3H]-pirenzepine.

  1984cited by this paper
• Tolerance to anticholinesterase compounds in mammals.

  1982cited by this paper
• Age-dependent effects of scopolamine on avoidance, locomotor activity, and rearing.

  1982cited by this paper
• Reduced muscarinic receptor binding in tissues of rats tolerant to the insecticide disulfoton.

  1981cited by this paper
• Altered [3H]quinuclidinyl benzilate binding in the striatum of rats following chronic cholinesterase inhibition with diisopropylfluorophosphate.

  1980cited by this paper
• Naloxone increases pain perception in rats and mice.

  1979cited by this paper
• Reduced binding of (3H)-quinuclidinyl benzilate associated with chronically low acetylcholinesterase activity.

  1979cited by this paper
• The effect of manipulation of cholinergic mechanisms on turning behaviour in mice with unilateral destruction of the nigro-neostriatal dopaminergic system.

  1978cited by this paper
• A rapid, simple radiometric assay for cholinesterase, suitable for multiple determinations.

  1975cited by this paper
• Postsynaptic localization of muscarinic cholinergic receptor binding in rat hippocampus.

  1974cited by this paper
• Inhibition of anticholinergic drug-induced locomotor stimulation in mice by alpha-methyltyrosine.

  1973cited by this paper
• Inhibition of anticholinergic drug-induced locomotor stimulation in mice by α-methyltyrosine

  1973cited by this paper
• REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

  1966cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Neuroinflammation and neurodegeneration in Huntington’s disease: genetic hallmarks, role of metals and organophosphates

  2025cites this paper
• Multiple neurological effects associated with exposure to organophosphorus pesticides in man.

  2022cites this paper
• The Effect of Low Doses of Chlorpyrifos on Blood and Bone Marrow Cells in Wistar Rats

  2022cites this paper
• Clinical Assessment of Acute Organophosphorus Pesticide Poisoning in Pediatric Patients Admitted to the Toxicology Emergency Department

  2022cites this paper
• Mitochondrial daysfunction from malathion and chlorpyrifos exposure is associated with degeneration of GABAergic neurons in Caenorhabditis elegans.

  2022cites this paper
• Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells.

  2021cites this paper
• Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats

  2021cites this paper
• Exposition prénatale aux pesticides organophosphorés et neurodéveloppement chez les jeunes enfants

  2019cites this paper
• Atropine counteracts the depressive-like behaviour elicited by acute exposure to commercial chlorpyrifos in rats.

  2019cites this paper
• Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring attention-deficit hyperactivity disorder and autistic traits

  2019cites this paper
• Long-term effects of low doses of Chlorpyrifos exposure at the preweaning developmental stage: A locomotor, pharmacological, brain gene expression and gut microbiome analysis.

  2019cites this paper
• Neurotoxic effects of organophosphorus pesticides and possible association with neurodegenerative diseases in man: A review.

  2018cites this paper
• The Neuroinflammatory Phenotype in a Mouse Model of Gulf War Illness is Unrelated to Brain Regional Levels of Acetylcholine as Measured by Quantitative HILIC-UPLC-MS/MS

  2018cites this paper
• Determinants of organophosphate pesticide exposure in pregnant women: A population-based cohort study in the Netherlands

  2018cites this paper
• Combined in silico and in vivo studies shed insights into the acute acetylcholinesterase response in rat and human brain

  2015cites this paper
• Comparative effects of parathion and chlorpyrifos on endocannabinoid and endocannabinoid-like lipid metabolites in rat striatum.

  2015cites this paper
• Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour.

  2015cites this paper
• The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats.

  2015cites this paper
• A Single High Dose of Chlorpyrifos Reduces Long-Term Basal C-Fos Expression in the Rat Arcuate Hypothalamic Nucleus

  2014cites this paper
• Guidelines for Neurotoxicity Risk Assessment

  2014cites this paper
• "Kamdhenu Ark" as a Genoprotective Agent Against Chlorpyrifos Induced Genotoxicity

  2014cites this paper
• Ameliorative effect of vitamin C on the haematological changes induced by exposure of chlorpyriphos and lead acetate in Wistar rats

  2014cites this paper
• Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression.

  2014cites this paper
• Toxicity and Novel Biomarkers of OP Exposure

  2014cites this paper
• Long term compulsivity on the 5-choice serial reaction time task after acute Chlorpyrifos exposure.

  2013cites this paper
• Dose-dependent regional brain acetylcholinesterase and acylpeptide hydrolase inhibition without cell death after chlorpyrifos administration.

  2013influential citation
• Noncholinesterase Protein Targets of Organophosphorus Pesticides

  2013cites this paper
• Comparative effects of parathion and chlorpyrifos on extracellular endocannabinoid levels in rat hippocampus: influence on cholinergic toxicity.

  2013cites this paper
• 12 Interaction Between Exposure to Neurotoxicants and Drug Abuse

  2012cites this paper
• Short-Term Sensorimotor and Cognitive Changes Induced by Acute Chlorpyrifos Exposure in Wistar Rats: Ameliorative Effect of Vitamin E

  2012cites this paper
• Ameliorative Effect of Vitamin E on Sensorimotor and Cognitive Changes Induced by Chronic Chlorpyrifos Exposure in Wistar Rats

  2012influential citation
• Low-Dose Sarin Exposure Produces Long Term Changes in Brain Neurochemistry of Mice

  2012cites this paper
• Cytotoxicity of chlopyrifos and cypermethrin: The ameliorative effects of antioxidants

  2012cites this paper
• Interaction Between Exposure to Neurotoxicants and Drug Abuse

  2012cites this paper
• Neurotoxic disorders and medical management of patients poisoned with organophosphorus pesticides

  2012cites this paper
• Assessing and Reducing Risk Due to Chlorpyrifos Use among Rice Farmers in Vietnam: From Probabilistic Risk Assessment to Safety Strategy Development

  2012cites this paper
• Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice.

  2011cites this paper
• COMPARATIVE EFFECTS OF CHLOPYRIFOS IN WILD TYPE AND CANNABINIOID CB1 RECEPTOR KNOCKOUT MICE

  2011cites this paper
• Ameliorative effects of vitamin C on short-term sensorimotor and cognitive changes induced by acute chlorpyrifos exposure in Wistar rats

  2010cites this paper
• Neurotoxic effects in patients poisoned with organophosphorus pesticides.

  2010cites this paper
• Chapter 70 – Chlorpyrifos

  2010cites this paper
• Vitamin C attenuates short-term hematological and biochemical alterations induced by acute chlorpyrifos exposure in Wistar rats

  2010cites this paper
• Neuropathological Studies of Chickens Following Exposure to Chlorpyrifos

  2010cites this paper
• Neuroprotective mechanisms induced in acute organophosphate poisoning.

  2010cites this paper
• Co-administration of Vitamins C and E Ameliorates Chronic Chlorpyrifos-induced Erythrocyte Osmotic Fragility in Wistar Rats

  2010cites this paper
• Sistema de seguimiento y análisis de la calidad del agua para consumo humano mediante el estudio de la respuesta comportamental en peces expuestos a sustancias tóxicas

  2010cites this paper
• Ameliorative Effect of Zinc on Chlorpyrifos-Induced Erythrocyte Fragility in Wistar Rats

  2010cites this paper
• Impulsivity as Long-Term Sequelae After Chlorpyrifos Intoxication: Time Course and Individual Differences

  2009cites this paper
• Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans

  2009cites this paper
• Assessment of chlorpyrifos and lead acetate combination on neurobehavioral aspects in Wistar rats after subchronic dietary exposure

  2009cites this paper
• Dendritic morphology on neurons from prefrontal cortex, hippocampus, and nucleus accumbens is altered in adult male mice exposed to repeated low dose of malathion

  2008cites this paper
• Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.

  2008cites this paper
• University of Southern Denmark Potential developmental neurotoxicity of pesticides used in Europe

  2008cites this paper
• Long-term monoamine changes in the striatum and nucleus accumbens after acute chlorpyrifos exposure.

  2008cites this paper
• Comparative in vivo effects of parathion on striatal acetylcholine accumulation in adult and aged rats.

  2007cites this paper
• CHLORPYRIFOS INCREASES THE LEVELS OF HIPPOCAMPAL NMDA RECEPTOR SUBUNITS NR2A AND NR2B IN JUVENILE AND ADULT RATS

  2007influential citation
• Effect of Withania somnifera on chlorpyrifos induced neurotoxicity in rats.

  2007cites this paper
• Cholinesterase inhibition and alterations of hepatic metabolism by oral acute and repeated chlorpyrifos administration to mice.

  2007cites this paper
• Time course of biochemical and behavioural effects of a single high dose of chlorpyrifos.

  2007cites this paper
• Long-lasting reductions of ethanol drinking, enhanced ethanol-induced sedation, and decreased c-fos expression in the Edinger-Westphal nucleus in Wistar rats exposed to the organophosphate chlorpyrifos.

  2006cites this paper
• Behavioral Toxicity of Cholinesterase Inhibitors

  2006cites this paper
• Vulnerability of long-term neurotoxicity of chlorpyrifos: effect on schedule-induced polydipsia and a delay discounting task

  2006influential citation
• Current issues in organophosphate toxicology.

  2006cites this paper
• Examination of Concurrent Exposure to Repeated Stress and Chlorpyrifos on Cholinergic, Glutamatergic, and Monoamine Neurotransmitter Systems in Rat Forebrain Regions

  2006cites this paper
• Cholinesterase inhibition and impacts on behavior of the Asian clam, Corbicula fluminea, after exposure to an organophosphate insecticide.

  2006cites this paper
• Neurochemical effects of chronic dietary and repeated high-level acute exposure to chlorpyrifos in rats.

  2005cites this paper
• Neurobehavioral effects of chronic dietary and repeated high-level spike exposure to chlorpyrifos in rats.

  2005cites this paper
• Effects of chronic dietary and repeated acute exposure to chlorpyrifos on learning and sustained attention in rats.

  2005cites this paper
• Behavioral sensitivity to amphetamine or scopolamine after acute administration of nicotine in the rat.

  2005cites this paper
• Long-term neurotoxicity of chlorpyrifos: spatial learning impairment on repeated acquisition in a water maze.

  2005cites this paper
• Amphetamine- and scopolamine-induced locomotor activity following treatment with chlorphenvinphos or chlorphyriphos in rats.

  2005influential citation
• A Case for Revisiting the Safety of Pesticides: A Closer Look at Neurodevelopment

  2005cites this paper
• Mechanistic Studies Investigating the Role of Organophosphate Insecticide Exposure in the Development and Exacerbation of Asthma

  2004cites this paper
• Long-term functional neurotoxicity of paraoxon and chlorpyrifos: behavioural and pharmacological evidence.

  2004cites this paper
• Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition.

  2004cites this paper
• Mechanisms of organophosphate insecticide-induced airway hyperreactivity.

  2004cites this paper
• Neurotoxic effect of dermally applied chlorpyrifos and cypermethrin. Reversibility of changes.

  2003cites this paper
• The Effect of Organophosphate Exposure on Neocortical, Hippocampal and Striatal Monoamines: A Potential Substrate for Chronic Psychiatric, Cognitive and Motor Dysfunction

  2003influential citation
• Pharmacokinetic profile and placental transfer of a single intravenous injection of [14C]chlorpyrifos in pregnant rats

  2002cites this paper
• Behavioural responsiveness to amphetamine or scopolamine following repeated exposure to chlorphenvinphos in rats.

  2002influential citation
• Changes in the Murine Nigrostriatal Pathway Following Pyrethroid and Organophosphate Insecticide Exposure: An Immunohistochemical Study

  2002cites this paper
• Inhibition of rat platelet 5-hydroxytryptamine uptake by chlorpyrifos and carbaryl.

  2001cites this paper
• Cognitive function and cholinergic neurochemistry in weanling rats exposed to chlorpyrifos.

  2001cites this paper
• Changes in EEG power spectra and behavioral states in rats exposed to the acetylcholinesterase inhibitor chlorpyrifos and muscarinic agonist oxotremorine.

  2001cites this paper
• Effects of sub-chronic in vivo chlorpyrifos exposure on muscarinic receptors and adenylate cyclase of rat striatum

  2001cites this paper
• Neurotoxic effect of dermally-applied chlorpyrifos and cypermethrin in Wistar rats.

  2001cites this paper
• The potential for toxic effects of chronic, low-dose exposure to organophosphates.

  2001cites this paper
• Comparing cognitive and screening tests for neurotoxicity. Effects of acute chlorpyrifos on visual signal detection and a neurobehavioral test battery in rats.

  2001cites this paper
• Neurotoxicology and Behavior

  2001influential citation
• Hyposensitivity to amphetamine following exposure to chlorphenvinphos--protection by amphetamine preexposure.

  2000cites this paper
• Chlorpyrifos-induced hypothermia and vasodilation in the tail of the rat: blockade by scopolamine.

  2000cites this paper
• Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity.

  2000cites this paper
• Determination of the reference dose for chlorpyrifos: proceedings of an expert panel.

  1999cites this paper
• Changes in rat brain cholinesterase activity and muscarinic receptor density during and after repeated oral exposure to chlorpyrifos in early postnatal development.

  1999cites this paper
• Effect of central and peripheral cholinergic antagonists on chlorpyrifos-induced changes in body temperature in the rat.

  1999cites this paper
• Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion.

  1998cites this paper
• Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos.

  1998cites this paper
• Learning and memory of rats after long-term administration of low doses of parathion.

  1998cites this paper
• Effects of Subchronic Administration of Metrifonate on Cholinergic Neurotransmission in Rats

  1998cites this paper
• Early biochemical detection of delayed neurotoxicity resulting from developmental exposure to chloropyrifos.

  1998cites this paper